Colon Cancer News and Research

Latest Colon Cancer News and Research

FDA grants accelerated approval to oncology drug for treatment of key genetic driver of cancer

The U.S. Food and Drug Administration today granted accelerated approval to Vitrakvi (larotrectinib), a treatment for adult and pediatric patients whose cancers have a specific genetic feature (biomarker).

27 Nov 2018

UH pharmaceutical scientist developing new drug to treat children with rare genetic disorder

A University of Houston pharmaceutical scientist is developing a new drug which could bring relief to children suffering with Familial Adenomatous Polyposis, a rare genetic disorder characterized by hundreds - if not thousands - of colorectal polyps.

21 Nov 2018

Regenstrief scientist calls for precision surveillance for colon cancer screening

The interval at which an individual undergoes a repeat colonoscopy because of previous pre-cancerous polyps -- a practice known as "surveillance" -- should be tailored to the individual and not simply be determined by the results of prior colonoscopies, according to Regenstrief Institute research scientist Thomas F. Imperiale, M.D.

8 Nov 2018

Biological factors not responsible for racial differences in colorectal cancer incidence

A systematic review and meta-analysis from the Regenstrief Institute and Indiana University School of Medicine has found that, in spite of the higher incidence and death rate of colorectal cancer in blacks, no difference exists in the overall prevalence of advanced, precancerous polyps between average-risk blacks and whites who underwent a screening colonoscopy.

24 Oct 2018

CRC incidence rates among young adults across Europe increasing by 6% every year

Data from 20 European national cancer registries was used to analyze trends in incidence rates of young adults with CRC across Europe over the last 25 years.

23 Oct 2018

Immunotherapy achieves major pathological response in early-stage mismatch repair deficient colon cancer

Pre-operative treatment with a combination of the immune checkpoint inhibitors nivolumab and ipilimumab achieves major pathological responses in 100% of early-stage colon cancers with mismatch repair deficiencies, according to results reported at ESMO 2018 from the first exploratory phase II trial to investigate this approach.

22 Oct 2018

$Phase III LONSURF study shows progression-free survival in patients with refractory metastatic gastric cancer$

Phase III LONSURF study shows progression-free survival in patients with refractory metastatic gastric cancer

Servier and Taiho Oncology, Inc. (U.S.), a subsidiary of Taiho Pharmaceutical Co., Ltd. (Japan), jointly announced today clinical data from the pivotal Phase III TAS-102 Gastric Study (TAGS) evaluating LONSURF® (trifluridine/tipiracil, TAS-102) versus placebo and best supportive care in patients with heavily pre-treated metastatic gastric cancer who have progressed or are intolerant to previous lines of therapy.

22 Oct 2018

Case Comprehensive Cancer Center wins NIH grant to study health disparities

The Case Comprehensive Cancer Center has received a three-year, $3,194,947 grant from the National Cancer Institute to investigate colorectal and breast cancer health disparities.

19 Oct 2018

Study shows close link between cytokine interleukin-1ß and obesity-promoted colon cancer

A new study describes the mechanistic relationship between the cytokine interleukin-1β, (IL-1β) and obesity, showing that when IL-1β levels are increased in obesity, IL-1 receptor signaling activates multiple pathways leading to colon cancer.

18 Oct 2018

Modeling Non-Numerical Data in Systems Biology

An interview with Dr. Eshan Mitra, discussing the importance of computer models in biology and the development of a more accurate model of the RAF phosphorylation pathway.

15 Oct 2018

Study unravels how cancer stem cells use normal genes in abnormal ways

CDK1 is a "normal" protein - its presence drives cells through the cycle of replication. And MHC Class I molecules are "normal" as well - they present bits of proteins on the surfaces of cells for examination by the immune system.

15 Oct 2018

Inflammatory proteins in the colon increase in parallel with increasing weight, study shows

Studies in mice have demonstrated that obesity-induced inflammation contributes to the risk of colorectal cancer, but evidence in humans has been scarce.

11 Oct 2018

Aspirin shown to prevent the spread of cancer

New research by Cardiff University has demonstrated a role for Aspirin in the treatment of bowel, prostate and breast cancer.

1 Oct 2018

Promising vaccine may provide new treatment option for patients with HER2-positive cancers

Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers who had not previously been treated with a HER2-targeted therapeutic, according to data from a phase I clinical trial presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3.

30 Sep 2018

New European School of Coloproctology launched by ESCP

The European Society of Coloproctology’s (ESCP) Education Committee has launched a new training school to help surgeons continue their professional education and development in the latest techniques of their field.

28 Sep 2018

Hybrid operating room enables faster diagnosis, treatment of patients with lung cancer

Representing a paradigm shift in thoracic surgery, the hybrid operating room combines three techniques into a single appointment eliminating multiple clinical visits for improved patient experience and outcomes.

25 Sep 2018

Researchers identify new genetic disorder in a human patient

Researchers from Michigan State University College of Human Medicine and physicians from Spectrum Health have identified for the first time in a human patient a genetic disorder only previously described in animal models.

21 Sep 2018

Study: Annual wellness visits improve delivery of preventive services in elderly population

new Harvey L. Neiman Health Policy Institute study assesses the effect of receiving an Annual Wellness Visit between 2011 and 2013 on the annual rate of eight preventive services recommended for the Medicare population following the AWV.

21 Sep 2018

CWRU receives NIH grant to learn how non-coding genes contribute to spread of colorectal cancer

Certain genes that code for proteins have long been known to contribute to cancer progression. But in a frame shift, researchers from Case Western Reserve University School of Medicine recently found that non-coding genes also contribute to the development and spreading of the disease, one of the first known examples of researchers doing so.

20 Sep 2018

UNC scientists reveal new approach to prevent obesity and diabetes

Scientists from the UNC School of Medicine discovered that the anti-inflammatory protein NLRP12 normally helps protect mice against obesity and insulin resistance when they are fed a high-fat diet.

19 Sep 2018

Colon Cancer News and Research

Latest Colon Cancer News and Research

FDA grants accelerated approval to oncology drug for treatment of key genetic driver of cancer

UH pharmaceutical scientist developing new drug to treat children with rare genetic disorder

Regenstrief scientist calls for precision surveillance for colon cancer screening

Biological factors not responsible for racial differences in colorectal cancer incidence

CRC incidence rates among young adults across Europe increasing by 6% every year

Immunotherapy achieves major pathological response in early-stage mismatch repair deficient colon cancer

Phase III LONSURF study shows progression-free survival in patients with refractory metastatic gastric cancer

Case Comprehensive Cancer Center wins NIH grant to study health disparities

Study shows close link between cytokine interleukin-1ß and obesity-promoted colon cancer

Modeling Non-Numerical Data in Systems Biology

Study unravels how cancer stem cells use normal genes in abnormal ways

Inflammatory proteins in the colon increase in parallel with increasing weight, study shows

Aspirin shown to prevent the spread of cancer

Promising vaccine may provide new treatment option for patients with HER2-positive cancers

New European School of Coloproctology launched by ESCP

Hybrid operating room enables faster diagnosis, treatment of patients with lung cancer

Researchers identify new genetic disorder in a human patient

Study: Annual wellness visits improve delivery of preventive services in elderly population

CWRU receives NIH grant to learn how non-coding genes contribute to spread of colorectal cancer

UNC scientists reveal new approach to prevent obesity and diabetes

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

Colon Cancer News and Research

Latest Colon Cancer News and Research

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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