Colon Cancer News and Research

Latest Colon Cancer News and Research

Study provides new insights into early events that shape cancer

A study led by researchers from Brigham and Women's Hospital suggests a new way to trace cancer back to its cell type of origin. By leveraging the epigenome maps produced by the Roadmap Epigenomics Program - a resource of data collected from over 100 cell types - the research team found that the unique genetic landscape of a particular tumor could be used to predict that tumor's cell type of origin.

19 Feb 2015

Oral pathogen protects different tumor cells from being killed by immune cells

Bacteria that are commonly found in the mouth are often abundant in patients with colon cancer, but the potential role these microbes play in tumor development has not been clear. A study published by Cell Press February 18th in the journal Immunity reveals that the oral pathogen Fusobacterium nucleatum protects a variety of tumor cells from being killed by immune cells.

12 Feb 2015

Scientists potentially discover new therapeutic targets to halt progression of tumor cells

Chronic inflammation is directly associated with several types of cancer, yet the reasons as to why this happens at a cellular level remain unclear. Now, an international team of scientists led by researchers at The Wistar Institute has identified a multistep process showing not only how these cancers develop but also potentially discovering new therapeutic targets that could halt the formation and progression of tumor cells.

10 Feb 2015

Combination therapies may overcome resistance to targeted cancer drugs

A protein called YAP, which drives the growth of organs during development and regulates their size in adulthood, plays a key role in the emergence of resistance to targeted cancer therapies, according to a new study led by UC San Francisco researchers.

10 Feb 2015

ECOG-ACRIN Cancer Research Group opens clinical trial for women with newly diagnosed DCIS

In direct response to recommendations made by a National Institutes of Health scientific consensus panel, the ECOG-ACRIN Cancer Research Group announced today the opening of E4112, a clinical trial for women with newly diagnosed ductal carcinoma in situ (DCIS) of the breast who, together with their doctors, will use the results of a magnetic resonance imaging (MRI) exam to determine whether to undergo a lumpectomy or a mastectomy.

6 Feb 2015

Study focuses on two natural approaches to preventing breast cancer

Preventing cancer requires intimate knowledge of how cancer starts, what causes it to grow and flourish, and how to stop it in its tracks. Sometimes this comes in the form of a vaccine (the HPV vaccine for cervical and head and neck cancers), a screening (a colonoscopy for colorectal cancer) or a blood test (the PSA level test for prostate cancer).

5 Feb 2015

Researchers are one step closer to devising an approach to identify pancreatic cancer earlier

Pancreatic cancer affects approximately 46,000 people each year in the United States and ranks fourth among the leading causes of cancer-related deaths. Only about 6 percent of individuals with pancreatic cancer will live five years after their diagnosis.

3 Feb 2015

Mathematical models of cancer behavior offer new insights on tumor growth

Hassan Fathallah-Shaykh, M.D., Ph.D., believes that math can transform medicine, and he has the numbers to prove it.

2 Feb 2015

Study discovers microRNA signatures that could predict prognosis, distant metastasis in colorectal cancer

A new study developed at the Center for Gastrointestinal Cancer Research and the Center for Epigenetics, Cancer Prevention and Cancer Genomics at Baylor Research Institute has discovered unique metastasis-specific microRNA signatures in primary colorectal cancers that could predict prognosis and distant metastasis in colorectal cancer.

31 Jan 2015

Study examines fear influenced colorectal cancer screening decisions in UK adults

People who worry about cancer are more likely to want to get screened for colon cancer, but feeling uncomfortable at the thought of cancer makes them less likely to actually go for the test, finds new UCL-led research.

30 Jan 2015

HCI researchers find cell mechanism that may trigger pancreatic cancer

Researchers at Huntsman Cancer Institute at the University of Utah have found that defects in how cells are squeezed out of overcrowded tissue to die, a process called extrusion, may be a mechanism by which pancreatic cancer begins. From these findings, they may have identified an effective way to reverse the defective extrusion's effects without destroying normal tissues nearby.

28 Jan 2015

Study finds that African-American people with colon cancer have lower survival rates

African-American people diagnosed with colon cancer have consistently lower survival rates compared with white patients, despite a nationwide decline in colon cancer deaths overall.

28 Jan 2015

PKC enzymes categorized as cancer promoters are actually tumor suppressors

Upending decades-old dogma, a team of scientists at the University of California, San Diego School of Medicine say enzymes long categorized as promoting cancer are, in fact, tumor suppressors and that current clinical efforts to develop inhibitor-based drugs should instead focus on restoring the enzymes' activities.

23 Jan 2015

Study finds increase in overall survival in patients with metastatic colorectal cancer

With the dawn of the modern era of new chemotherapeutic and biologic agents available for managing their disease, patients with metastatic colorectal cancer are undergoing less surgery for the removal of their primary tumors, according to research from The University of Texas MD Anderson Cancer Center.

14 Jan 2015

High vitamin D levels boost survival for metastatic colorectal cancer patients

According to a new study led by researchers at Dana-Farber Cancer Institute, clinical trial patients with metastatic colorectal cancer who had high levels of vitamin D in their bloodstream prior to treatment with chemotherapy and targeted drugs, survived longer, on average, than patients with lower levels of the vitamin.

14 Jan 2015

Sirnaomics submits STP705 IND Application to CFDA for skin scar treatment

Sirnaomics, Inc. and its affiliate Suzhou Sirnaomics Pharmaceutics, Co. Ltd., together with its partner Guangzhou Xiangxue Pharmaceutical, Co. Ltd., (SZSE: 300147), have formally submitted an Investigational New Drug (IND) Application to the China Food and Drug Administration for STP705, an anti-fibrosis RNA interference (RNAi) therapeutic for prevention and treatment of human skin hypertrophic scars.

5 Jan 2015

Johns Hopkins scientists create statistical model to measure proportion of cancer incidence

Scientists from the Johns Hopkins Kimmel Cancer Center have created a statistical model that measures the proportion of cancer incidence, across many tissue types, caused mainly by random mutations that occur when stem cells divide.

2 Jan 2015

Mayo Clinic researchers correctly evaluate polyps using high-definition optical lenses

It may not be necessary for experienced gastroenterologists to send polyps they remove from a patient's colon to a pathologist for examination, according to a large study conducted by physician researchers at the Jacksonville campus of Mayo Clinic.

19 Dec 2014

Bacterial biofilms may increase colon cancer risk

Researchers from Johns Hopkins have found that dense mats of interacting bacteria, called biofilms, were present in the majority of cancers and polyps, particularly those on the right side of the colon. The presence of these bacterial bunches, they say, may represent an increased risk for colon cancer and could form the basis of new diagnostic tests.

17 Dec 2014

Novartis announces FDA approval of Signifor LAR for treatment of patients with acromegaly

Novartis announced today that the US Food and Drug Administration has approved Signifor long-acting release (LAR) (pasireotide) for injectable suspension, for intramuscular use, for the treatment of patients with acromegaly who have had an inadequate response to surgery and/or for whom surgery is not an option.

16 Dec 2014

Colon Cancer News and Research

Latest Colon Cancer News and Research

Study provides new insights into early events that shape cancer

Oral pathogen protects different tumor cells from being killed by immune cells

Scientists potentially discover new therapeutic targets to halt progression of tumor cells

Combination therapies may overcome resistance to targeted cancer drugs

ECOG-ACRIN Cancer Research Group opens clinical trial for women with newly diagnosed DCIS

Study focuses on two natural approaches to preventing breast cancer

Researchers are one step closer to devising an approach to identify pancreatic cancer earlier

Mathematical models of cancer behavior offer new insights on tumor growth

Study discovers microRNA signatures that could predict prognosis, distant metastasis in colorectal cancer

Study examines fear influenced colorectal cancer screening decisions in UK adults

HCI researchers find cell mechanism that may trigger pancreatic cancer

Study finds that African-American people with colon cancer have lower survival rates

PKC enzymes categorized as cancer promoters are actually tumor suppressors

Study finds increase in overall survival in patients with metastatic colorectal cancer

High vitamin D levels boost survival for metastatic colorectal cancer patients

Sirnaomics submits STP705 IND Application to CFDA for skin scar treatment

Johns Hopkins scientists create statistical model to measure proportion of cancer incidence

Mayo Clinic researchers correctly evaluate polyps using high-definition optical lenses

Bacterial biofilms may increase colon cancer risk

Novartis announces FDA approval of Signifor LAR for treatment of patients with acromegaly

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

Colon Cancer News and Research

Latest Colon Cancer News and Research

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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