Colon Cancer News and Research

Latest Colon Cancer News and Research

Research findings may help personalize use of statins, scientists say

Researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center have discovered why statins -- popular drugs that lower cholesterol and appear to protect against colorectal cancer development -- work for some people, but not for all.

22 Apr 2010

Seattle Genetics, Agensys present ASG-5ME ADC preclinical data at 101st AACR

Seattle Genetics, Inc. and Agensys, Inc., an affiliate of Tokyo-based Astellas Pharma Inc., today reported preclinical data with ASG-5ME, an antibody-drug conjugate (ADC) that is being co-developed by both companies for the treatment of solid tumors. In models of human prostate and pancreatic cancer, ASG-5ME was found to have potent and long lasting antitumor activity. The findings were presented at the 101st Annual Meeting of the American Association for Cancer Research (AACR) being held in Washington, D.C.

22 Apr 2010

NO-naproxen blocks molecular changes leading to colorectal cancer development

Past randomized clinical trials have shown that non-steroidal anti-inflammatory drugs (NSAIDs), including naproxen, can reduce the risk of colon cancer and precancerous polyps in humans. Now, researchers at Fox Chase Cancer Center have found that an investigational form of naproxen, called nitric oxide-donating naproxen (NO-naproxen), can block one of the earliest molecular changes that lead to colorectal cancer development while also reducing gastrointestinal toxicity, a relatively common side effect associated with NSAIDs.

22 Apr 2010

Study: Scientists advance toward development of urine test for detecting colon cancer

Scientists are reporting an advance toward development of a urine test for detecting colon cancer, the third most common cancer in the United States. Such a test could eventually compliment or even reduce the need for colonoscopy, the mainstay screening test used today. The study, which analyzes chemical differences in the urine of humans with and without colon cancer, is in ACS' Journal of Proteome Research, a monthly publication.

22 Apr 2010

Alchemia’s HyACT tumour targeting technology enhances killing of cancer stem cells

Alchemia's subsidiary Alchemia Oncology today presented two posters at the American Association of Cancer Research (AACR) 101st Annual Meeting in Washington, DC. The data demonstrates the ability of the Company's HyACT tumour targeting technology to dramatically enhance the killing of cancer stem cells. These cells are highly resistant to treatment with chemotherapeutic drugs and are believed to be responsible for treatment failure and disease recurrence.

21 Apr 2010

Positive preclinical pharmacokinetic data for XMT-1001 presented at AACR 2010

Mersana Therapeutics, a platform-based cancer therapeutics company, announced today positive preclinical pharmacokinetic data for its lead development candidate, XMT-1001, which is currently in a Phase 1 clinical trial in patients with advanced solid tumors. The results were presented in a poster session at the AACR 101st Annual Meeting 2010 in Washington, DC, held April 17-21, 2010.

21 Apr 2010

Immunomedics reports study results of antibody-SN-38 conjugates for targeted cancer chemotherapy

Immunomedics, Inc., a biopharmaceutical company focused on developing monoclonal antibodies to treat cancer and other serious diseases, reported today at the 101st Annual Meeting of the American Association for Cancer Research (AACR) results from two studies aimed at improving the design of antibody-SN-38 conjugates for targeted cancer chemotherapy.

21 Apr 2010

Gene test predicts statins' effectiveness in reducing risk of colorectal cancer

A genetic test can help determine in which patients cholesterol-lowering statin drugs might have the most benefit in also reducing the risk of colorectal cancer, a new study from researchers at the University of Michigan Comprehensive Cancer Center finds.

21 Apr 2010

Vitamin D intake from foods, supplements may not predict relationship between cancer and vitamin D

Vitamin supplements, diet, geographic location, demographic information or lifestyle, independently or in combination, cannot accurately predict vitamin D concentrations in blood, researchers at the University at Buffalo have found.

21 Apr 2010

MUC1 expression indicates progression of pediatric inflammatory bowel disease

Millions of people are afflicted with inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis, and 30 percent of new cases occur in childhood. Mucin 1, an epithelial mucin that has been shown to elicit both an immune response and to have altered glycosylation in disease, may be a noninvasive indicator of the progression of these illnesses.

20 Apr 2010

Blood test to determine inflammation levels in body may help assess colon cancer risk: Study

A blood test used to determine the level of inflammation in the body may offer some help in assessing colon cancer risk, according to results of a study to be presented by Vanderbilt-Ingram Cancer Center's Gong Yang, M.D., MPH, at the 101st Annual Meeting of the American Association for Cancer Research.

20 Apr 2010

UAB researchers discover four miRNAs to assess survival rate of colorectal cancer patients

Researchers at the University of Alabama at Birmingham Department of Pathology have discovered a set of four biomarkers that will help predict which patients are more likely to develop aggressive colorectal cancer and which are not. The findings also shed light on the genetics that result in worse colorectal cancer-treatment outcomes for African-Americans, compared with Caucasians, the researchers said.

20 Apr 2010

New research shows link between infection-related diseases and risk of cancer

New research is emerging that suggests a link between infection-related diseases and risk of cancer, according to findings presented here at the American Association for Cancer Research 101st Annual Meeting 2010.

20 Apr 2010

Biomarkers to help predict development of aggressive colorectal cancer discovered

Researchers at the University of Alabama at Birmingham (UAB) Department of Pathology have discovered a set of four biomarkers that will help predict which patients are more likely to develop aggressive colorectal cancer and which are not. The findings also shed light on the genetics that result in worse colorectal cancer-treatment outcomes for African-Americans, compared with Caucasians, the researchers said.

19 Apr 2010

Radiolabeled hedgehog can differentiate stem-like cancer cells, identify aggressive tumors

At the American Association for Cancer Research 101st Annual Meeting 2010, scientists and clinicians will present more than 6,300 abstracts dealing with innovative aspects of biology, technology and emerging therapies.

19 Apr 2010

Study reveals increased risk for cancer among Latino populations

New findings from epidemiology and observational studies show an increased risk for cancer among Latino populations, but unique demographic characteristics suggest the problem may be worse than currently known.

19 Apr 2010

Results of study comparing REMICADE to azathioprine for Crohn's disease published

Findings published today in The New England Journal of Medicine from a first-of-its-kind comparator trial evaluating the anti-tumor necrosis factor (TNF)-alpha biologic treatment REMICADE (infliximab) in the treatment of moderately to severely active Crohn's disease in patients who were naive to immunomodulator and biologic therapy, showed that a significantly greater proportion of patients receiving REMICADE achieved steroid-free remission and mucosal healing compared with patients receiving azathioprine.

16 Apr 2010

Exclusive licensing practices slows innovation in gene testing market

Exclusive licenses to gene patents, most of which are held by academic institutions and based on taxpayer-funded research, do more to block competition in the gene testing market than to spur the development of new technologies for gauging disease risk, say researchers at the Duke Institute for Genome Sciences & Policy (IGSP).

15 Apr 2010

ICGC: New era of personalised medicine for cancer patients

Published online today in Nature, a paper authored by over 200 members of the International Cancer Genome Consortium describes the beginnings of a Brave New World, a new era of personalised medicine for cancer patients.

15 Apr 2010

Inflammasome components help protect against colitis

Particular components of inflammasomes-protein complexes needed for generating immune responses to pathogens and cellular damage-lessen the severity of colitis and colitis-associated colon cancer in mice, according to a study published online this week in the Journal of Experimental Medicine.

13 Apr 2010

Colon Cancer News and Research

Latest Colon Cancer News and Research

Research findings may help personalize use of statins, scientists say

Seattle Genetics, Agensys present ASG-5ME ADC preclinical data at 101st AACR

NO-naproxen blocks molecular changes leading to colorectal cancer development

Study: Scientists advance toward development of urine test for detecting colon cancer

Alchemia’s HyACT tumour targeting technology enhances killing of cancer stem cells

Positive preclinical pharmacokinetic data for XMT-1001 presented at AACR 2010

Immunomedics reports study results of antibody-SN-38 conjugates for targeted cancer chemotherapy

Gene test predicts statins' effectiveness in reducing risk of colorectal cancer

Vitamin D intake from foods, supplements may not predict relationship between cancer and vitamin D

MUC1 expression indicates progression of pediatric inflammatory bowel disease

Blood test to determine inflammation levels in body may help assess colon cancer risk: Study

UAB researchers discover four miRNAs to assess survival rate of colorectal cancer patients

New research shows link between infection-related diseases and risk of cancer

Biomarkers to help predict development of aggressive colorectal cancer discovered

Radiolabeled hedgehog can differentiate stem-like cancer cells, identify aggressive tumors

Study reveals increased risk for cancer among Latino populations

Results of study comparing REMICADE to azathioprine for Crohn's disease published

Exclusive licensing practices slows innovation in gene testing market

ICGC: New era of personalised medicine for cancer patients

Inflammasome components help protect against colitis

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Colon Cancer News and Research

Latest Colon Cancer News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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