Colorectal Cancer

Colorectal Cancer is cancer that develops in the colon (the longest part of the large intestine) and/or the rectum (the last several inches of the large intestine before the anus). In the United States, it is the fourth most common cancer in men and women. Caught early, it is often curable.

What Causes Colorectal Cancer?

Cancer occurs when a normal cell divides and multiples uncontrollably. Normally cells are regulated in their growth, maturity, division and death by the DNA present in their nucleus. With damage to the DNA the cells may become rogue and multiply uncontrollably to give rise to tumors.

What is Colorectal Cancer?

Colorectal Cancer Diagnosis

Colorectal Cancer Prevention

Colorectal Cancer Management

Colorectal Cancer Prognosis

Colorectal Cancer Symptoms

Colorectal Cancer Pathogenesis

Microbial Dysbiosis and Colorectal Cancer

Colorectal Cancer and Organ Preservation

Latest Colorectal Cancer News and Research

Novel photosensitizer Ce6-GFFY shows promise for colorectal cancer therapy

A new publication from Genes & Diseases; DOI 10.1016/j.gendis.2024.101441, discusses how Ce6-GFFY is a novel photosensitizer for colorectal cancer therapy.

20 Dec 2024

He went in for a colonoscopy. The hospital charged $19,000 for two.

Tom Contos is an avid runner. When he started experiencing rectal bleeding in March, he thought exercise could be the cause and tried to ignore it. But he became increasingly worried when the bleeding continued for weeks.

19 Dec 2024

New molecular imaging agent can accurately identify crucial cancer biomarker

A new molecular imaging agent can accurately identify a crucial biomarker found among many different types of cancer.

18 Dec 2024

Microbial bile acids affect colon cancer risk in opposite ways

Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats.

16 Dec 2024

Exploring the cytotoxic potential of neocryptolepine derivatives against cancer

Announcing a new publication for Acta Materia Medica journal. Cancer has been a severe public health and social problem, a leading disease that has diminished the quality of life, and a barrier to improving life expectancy.

13 Dec 2024

Strategies to overcome social challenges in cancer prevention

Researchers at University of California San Diego and collaborating institutions have shed light on the ways that social risks, such as housing or food insecurity, pose barriers to routine cancer screenings.

13 Dec 2024

DTI detects precancerous lesions in the pancreas

Precursor lesions of pancreatic cancer are very difficult to characterize with magnetic resonance imaging (MRI). But now, in a new study, researchers led by Noam Shemesh and Carlos Bilreiro – respectively head of the Preclinical MRI lab at Champalimaud Research and a doctor at the Champalimaud Clinical Centre's Radiology Department – have shown, for the first time, that a particular form of MRI, called Diffusion Tensor Imaging (DTI), is capable of robustly detecting pre-malignant lesions in the pancreas.

13 Dec 2024

Lipid imbalances hold the key to chronic inflammation in colon cancer

Scientists uncover how disrupted lipid metabolism fuels chronic inflammation in colorectal cancer, offering insights into new therapeutic strategies targeting pro-inflammatory and pro-resolving lipid imbalances.

12 Dec 2024

Study highlights global surge in early-onset colorectal cancer

A new study led by American Cancer Society (ACS) researchers shows that early-onset colorectal cancer (CRC) incidence rates are rising in 27 of 50 countries/territories worldwide, 20 of which have either exclusive or faster increases for early-onset disease.

11 Dec 2024

Accelerated aging linked to early-onset colorectal cancer, study shows

New research from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine suggests that one's biological age, which can be higher than his or her chronological age – a concept called accelerated aging – may predict who's at risk for developing colon polyps, a known risk factor for colorectal cancer.

11 Dec 2024

Ultra-processed foods dominate American home diets

A new analysis led by researchers at the Johns Hopkins Bloomberg School of Public Health found that more than half of calories consumed at home by adults in the U.S. come from ultraprocessed foods.

11 Dec 2024

Study links Western diet to chronic inflammation and colorectal cancer growth

Colorectal cancer, the second leading cause of cancer-related deaths in the United States, may be fueled by the food on our plates.

10 Dec 2024

Bacterial toxin may fuel colorectal cancer metastasis

A toxin in the bacteria that's one of the most common causes of foodborne illness accelerates the spread of colorectal tumors to other parts of the body, a study led by UF Health Cancer Center researchers and international collaborators has found.

6 Dec 2024

Dual-antibody therapy shows promise in treating metastatic colorectal cancer

Metastatic colorectal cancer (mCRC) remains a daunting challenge, especially after first-line treatments fail.

6 Dec 2024

E.coli toxin-producing bacteria linked to bladder and bowel cancer

Certain intestinal bacteria are found more frequently in countries such as Norway than in a number of other countries and there is also a higher incidence of bladder cancer, bowel cancer and prostate cancer.

6 Dec 2024

45 years of progress: Prevention and screening avert millions of cancer deaths

Research shows that cancer prevention and screening efforts prevented 5.94 million deaths across five major cancer types, highlighting their critical role.

6 Dec 2024

Extracellular vesicle DNA regulates immune responses and suppresses liver metastasis

The study highlights how EV-DNA packaging influences immune responses and its promise as a biomarker for assessing colorectal cancer metastasis risk.

6 Dec 2024

New study links specific E. coli strains to higher cancer incidence rates

Higher rates of certain cancers in countries, such as the UK, may be linked to two particular strains of bacteria.

6 Dec 2024

Cancer prevention and screening avert more deaths than treatment advances

Improvements in cancer prevention and screening have averted more deaths from five cancer types combined over the past 45 years than treatment advances, according to a modeling study led by researchers at the National Institutes of Health (NIH).

5 Dec 2024

Tumor secreted DNA triggers immune response against liver metastasis Special...

Specially packaged DNA secreted by tumor cells can trigger an immune response that inhibits the metastatic spread of the tumor to the liver, according to a study led by researchers at Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and Korea's Yonsei University.

4 Dec 2024