Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

Brain-derived protein in colorectal cancer

Tumor progression is usually ensured by more than one proliferative mechanism. When one of these is shut down by a specifically targeted drug, other mechanisms may emerge. While these events may lead to treatment failure, they may also become an opportunity for researchers to identify novel targets to be further explored.

27 Apr 2011

Positive results from Sanofi-aventis and Regeneron ZALTRAP Phase III study in mCRC

Sanofi-aventis and Regeneron Pharmaceuticals, Inc. announced that the Phase III VELOUR trial evaluating the investigational agent ZALTRAP, also known as VEGF Trap, in combination with the FOLFIRI chemotherapy regimen versus a regimen of FOLFIRI plus placebo met its primary endpoint of improving overall survival in the second-line treatment of metastatic colorectal cancer.

27 Apr 2011

Colorectal cancer patients with genetic mutation can benefit from new class of drugs

A class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University of Michigan Comprehensive Cancer Center finds.

26 Apr 2011

Study: 80% of blacks more likely to spend all personal finances for cancer care

People in minority groups, especially black Americans, are more willing than their white counterparts to exhaust their personal financial resources to prolong life after being diagnosed with lung or colorectal cancer, according to a University of Alabama at Birmingham study published April 26, 2011, online in Cancer, the journal of the American Cancer Society.

26 Apr 2011

Analysis of the health law's effects continues

Reports look at the diverse effects of the health law — from Medicare and Medicaid to the accountable care organizations.

25 Apr 2011

FDA approves Spectrum's FUSILEV Injection to treat metastatic colorectal cancer

Spectrum Pharmaceuticals, a biotechnology company with fully integrated commercial and drug development operations with a primary focus in oncology, today announced that the U.S. Food and Drug Administration has approved the Company's Supplemental New Drug Application for FUSILEV Injection.

22 Apr 2011

Nature solves complex topological puzzles in DNA substrate recognition with elegant simplicity

A major discovery about an enzyme's structure has opened a window on understanding DNA repair. Scientists at Duke University Medical Center have determined the structure of a nuclease that will help scientists to understand several DNA repair pathways, a welcome development for cancer research.

21 Apr 2011

Ludwig Institute demonstrates ability of DAVANAT to enhance efficacy of T-lymphocytes to kill tumor cells

Pro-Pharmaceuticals, Inc. today announced that the Brussels Branch of the Ludwig Institute for Cancer Research demonstrated the ability of GM-CT-01 (DAVANAT®) to enhance the ability of tumor-specific T-lymphocytes to kill tumor cells.

20 Apr 2011

Oncolytics announces interim data from REOLYSIN translational clinical trial in metastatic colorectal cancer

Oncolytics Biotech Inc. today announced interim data from a U.K. translational clinical trial (REO 013) investigating intravenous administration of REOLYSIN in patients with metastatic colorectal cancer prior to surgical resection of liver metastases. The principal investigator of the study was Professor Alan Melcher of Leeds Institute of Molecular Medicine, University of Leeds, UK.

20 Apr 2011

Advancell initiates ATH008 phase IIb study for hand-foot syndrome

ADVANCELL, an emerging Spanish biopharmaceutical company, has initiated a phase IIb clinical study of the Company's ATH008, for the treatment of the palmar-plantar erythrodysesthesia syndrome, also known as hand-foot syndrome, a painful side-effect of certain chemotherapies such as capecitabine and fluoropyrimidines.

20 Apr 2011

Biothera's Phase II clinical trials in lung cancer attain stage 1 endpoint

Biothera announced today that its second Phase II non-small cell lung cancer trial, evaluating Imprime PGG® in combination with bevacizumab (Avastin®) and two chemotherapeutic agents, has achieved its stage 1 endpoint and has begun enrolling patients for stage 2 of the study.

20 Apr 2011

Japan Tobacco and Torii commence ferric citrate Phase 3 clinical program for hyperphosphatemia

Keryx Biopharmaceuticals, Inc., announced today that its Japanese partner, Japan Tobacco Inc. (JT) and Torii Pharmaceutical Co., Ltd., JT's pharmaceutical business subsidiary, has commenced the Phase 3 clinical program of ferric citrate in Japan for the treatment of patients with hyperphosphatemia.

18 Apr 2011

Scientists identify novel small molecules that block human tumor cell growth

Researchers from the Cancer Institute at NYU Langone Medical Center have identified three novel small molecules that interrupt a crucial cellular communication pathway that regulates many aspects of development and cancer.

15 Apr 2011

Study: Significant variation found in results of bowel cancer surgery across English NHS hospitals

There is worrying variation in the results of bowel cancer surgery across NHS hospitals in England with some having many more patient deaths immediately after surgery than others, according to new research funded by Cancer Research UK and published today in Gut.

12 Apr 2011

Bowel cancer surgery survival rates “worrying” experts

In a new study that looked into post-operative death rates for one of the most common cancers, trends look worrying. On average 6.7% of patients died within a month of undergoing surgery for bowel cancer in England between 1998 and 2006. Patients face a seven-fold higher risk of dying after surgery in some NHS trusts than others, the study shows.

11 Apr 2011

CINJ experts to comment on vaccine therapy and biomedical informatics

April marks National Cancer Control Awareness Month, which focuses on the importance of prevention, treatment, and research. Making significant contributions in all of these areas is The Cancer Institute of New Jersey, one of the nation's 40 Comprehensive Cancer Centers as designated by the National Cancer Institute and the only such center in New Jersey.

11 Apr 2011

Pfizer to support immatics' IMA901 Phase III trial in advanced renal cell carcinoma

immatics biotechnologies GmbH, a clinical-stage biopharmaceutical company developing advanced therapeutic vaccines that are active against cancer, today announced that Pfizer has agreed to support its pivotal Phase III trial with IMA901, its therapeutic cancer vaccine for advanced renal cell carcinoma.

11 Apr 2011

Two new studies on Veterans Affairs health care system

As recently as the 1990s, the Veterans Affairs health care system had a subpar reputation for quality, but two new studies of standard quality metrics, both led by Amal Trivedi, assistant professor of community health at Brown University and a physician at the Providence VA Medical Center, show that the system that cares for more than 5 million patients has improved markedly in the last decade.

8 Apr 2011

Cancer screening updates

Everyone in England aged 55 to 59 will be invited for a new test which could dramatically cut their chances of developing bowel cancer. This new test could save an extra 3,000 lives every year after the UK National Screening Committee gave the nod for it to be added to the NHS programme. The test known as Flexible sigmoidoscopy (FS) differs to the current faecal occult blood (FOB) test, which relies on people sending off stool samples.

7 Apr 2011

Alcohol raises risk of cancers: Study

This comes from a large Europe-wide study published in the British Medical Journal that found that one-in-10 of all cancers in men and one-in-33 of all cancers in women are caused by past or current alcohol intake. For alcohol-related cancers, one-in-three in men and one-in-20 in women are caused by any excessive drinking. According to cancer charities say people should limit their drinking to lower the risk.

7 Apr 2011

Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

Brain-derived protein in colorectal cancer

Positive results from Sanofi-aventis and Regeneron ZALTRAP Phase III study in mCRC

Colorectal cancer patients with genetic mutation can benefit from new class of drugs

Study: 80% of blacks more likely to spend all personal finances for cancer care

Analysis of the health law's effects continues

FDA approves Spectrum's FUSILEV Injection to treat metastatic colorectal cancer

Nature solves complex topological puzzles in DNA substrate recognition with elegant simplicity

Ludwig Institute demonstrates ability of DAVANAT to enhance efficacy of T-lymphocytes to kill tumor cells

Oncolytics announces interim data from REOLYSIN translational clinical trial in metastatic colorectal cancer

Advancell initiates ATH008 phase IIb study for hand-foot syndrome

Biothera's Phase II clinical trials in lung cancer attain stage 1 endpoint

Japan Tobacco and Torii commence ferric citrate Phase 3 clinical program for hyperphosphatemia

Scientists identify novel small molecules that block human tumor cell growth

Study: Significant variation found in results of bowel cancer surgery across English NHS hospitals

Bowel cancer surgery survival rates “worrying” experts

CINJ experts to comment on vaccine therapy and biomedical informatics

Pfizer to support immatics' IMA901 Phase III trial in advanced renal cell carcinoma

Two new studies on Veterans Affairs health care system

Cancer screening updates

Alcohol raises risk of cancers: Study

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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