Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

Postmenopausal women undergoing combination hormone therapy at increased risk of heart disease: WHI confirms

New analyses from the Women's Health Initiative (WHI) confirm that combination hormone therapy increases the risk of heart disease in healthy postmenopausal women. Researchers report a trend toward an increased risk of heart disease during the first two years of hormone therapy among women who began therapy within 10 years of menopause, and a more marked elevation of risk among women who began hormone therapy more than 10 years after menopause. Analyses indicate that overall a woman's risk of heart disease more than doubles within the first two years of taking combination HT.

17 Feb 2010

Certain patients with IBD at increased risk of developing colorectal cancer: AGA's new guidelines

Certain patients with inflammatory bowel disease (IBD), both ulcerative colitis and Crohn's disease of the colon, have an increased risk of developing colorectal cancer compared to individuals without IBD. A number of factors contribute to the increase in risk, which necessitates an individualized and sensible approach to surveillance in patients, according to a new medical position statement and technical review published by the American Gastroenterological Association in its official journal, Gastroenterology.

17 Feb 2010

Research roundup: Bundled payments, PTSD incidence, cost of treating immigrants

This paper examines the spending for health care of adult naturalized citizens and immigrant noncitizens (including some undocumented immigrants) compared to U.S. natives, as documented in data from the 1999-2006 Medical Expenditure Panel Surveys (MEPS): "inflation and age-adjusted health care expenditures among noncitizen immigrants were consistently … lower than those of naturalized citizens and U.S. natives during 1999-2006."

15 Feb 2010

PAN to provide co-payment assistance for medications to underinsured patients through five new funds

Patient Access Network Foundation will expand its services to provide co-payment assistance for medications to underinsured patients through five new funds -- including grants of up to $10,000 per year for prostate cancer patients.

12 Feb 2010

HDC signs agreement to receive clinical specimens for colon cancer molecular diagnostic test

Health Discovery Corporation announced today that the Company has entered into an exclusive agreement with the Pancreas, Biliary and Liver Surgery Center of New York at Saint Vincent Catholic Medical Centers in New York City to provide clinical specimens to be utilized to complete the final validation of HDC's molecular diagnostic test for colon cancer. This test demonstrated a 93% Sensitivity and a 93% Specificity in a previous validation study.

11 Feb 2010

Medicinal chemistry paper related to the discovery of CUDC-101 published

Curis, Inc., a drug development company seeking to develop next generation targeted small molecule drug candidates for cancer treatment, today announced that a medicinal chemistry paper related to the discovery of CUDC-101, Curis’s HDAC, EGFR and Her2 inhibitor, was published online in the Journal of Medicinal Chemistry and also will be published in an upcoming print version of the journal.

10 Feb 2010

Insight into mechanism H. pylori uses to evade the immune system

Helicobacter pylori (H. pylori) is the causal agent of chronic gastritis, ulcer and gastric cancer. It has the potential to persist in the human stomach for decades, sometimes causing neither harm nor clinical symptoms. Nevertheless, on some occasions, depending on the host immune system and the strain causing the infection, the outcome can be very serious. To maintain the infection, the bacterium must adapt to survive the host defences. One way to accomplish this is to sequentially change the external proteins on the bacterial surface.

10 Feb 2010

Study provides new data about potential risk of gastric cancer in patients with intestinal metaplasia

Gastric cancer remains a significant problem globally. The relationship between intestinal metaplasia (IM) and gastric cancer has always been controversial. Generally IM is divided into subtypes on the basis of histochemical characteristics; however, this classification is confusing.

10 Feb 2010

Study explores link between HBV genotype C and liver cirrhosis

Hepatitis B virus (HBV) genotypes have distinct geographical distributions, and have been shown to differ with regard to clinical outcome and prognosis. However, the relationship between HBV genotypes and liver cirrhosis remains controversial and no study on exploring the association between HBV genotypes and subclinical cirrhosis in community-based population has been reported.

10 Feb 2010

Study shows lactobacillus is effective in improving H. pylori-infected diseases

Helicobacter pylori (H. pylori) are considered to be the most important etiological agents of chronic gastritis. The eradication of H. pyloridepends on the combination of antibiotics and acid suppression drugs.

10 Feb 2010

Data provide key information about epigenetic profiles for gastric cancer

Gastric cancer, one of the most common types of cancer, is associated with high mortality rates. In the last decades, a decrease in the worldwide incidence has been observed with some changes in the therapeutic and diagnostic options.

10 Feb 2010

Johns Hopkins Hospital initiates Phase I trial with Neogenix's NPC-1C

Neogenix Oncology, Inc. (Neogenix) announced today that the Johns Hopkins Hospital has initiated a Phase I trial with the company’s first therapeutic antibody, NPC-1C, in patients with late stage pancreatic or colorectal cancer.

10 Feb 2010

IgM/IgG ratio is useful in diagnosing primary biliary cirrhosis

Previous studies have shown that assessment of immunoglobulin subclasses in plasma cells by immunohistochemistry (IHC) may be useful in the histopathologic evaluation of autoimmune liver diseases. However, further studies are necessary in order to validate the diagnostic utility of IgM and IgG immunohistochemistry in this specific scenario.

10 Feb 2010

Insurer to take new role in assessing cancer treatments

UnitedHealthcare, one of the nation's biggest insurance companies, has decided to take a more active role in the care of its policy holders who are being treated for several types of cancer, The Wall Street Journal reports.

9 Feb 2010

Racial disparities continue in U.S. cancer screening practices

The incidence of advanced breast cancer diagnosis among black women remained 30 percent to 90 percent higher compared to white women between 1992 and 2004, according to new findings by researchers at Fred Hutchinson Cancer Research Center. In addition, the disparity in the incidence of advance colorectal cancer actually widened over this time period as rates fell among whites but increased slightly among blacks.

9 Feb 2010

Combination of blueberries and probiotics protects against intestinal disorders

It is already known that blueberries are rich in antioxidants and vitamins. New research from the Lund University Faculty of Engineering in Sweden shows that blueberry fibre are important and can alleviate and protect against intestinal inflammations, such as ulcerative colitis.

9 Feb 2010

Study may provide new intervention strategies for esophageal adenocarcinoma

Barrett's epithelium is recognized as a complication of erosive esophagitis and is the pre-malignant condition for adenocarcinoma of the esophagus.

6 Feb 2010

Study suggests environmental factors play a significant role in the etiology of Crohn's disease

Although inflammatory bowel disease (IBD) [comprising mainly Crohn's disease (CD) and ulcerative colitis (UC)] is thought to affect about 150 000 people in the United Kingdom, the prevalence of severe IBD is not known. Mortality following hospitalization for IBD is significant but little has been reported on long-term follow-up.

6 Feb 2010

Endoscopic surveillance could be an appropriate strategy for subepithelial lesions

Although several studies pertaining to the natural history of subepithelial tumors have been published, they have been limited by small sample size and relatively short follow-up. The natural history of subepithelial lesions has not been clearly elucidated, and the appropriate management strategy for small subepithelial tumors is still controversial.

6 Feb 2010

Survey finds majority of patients are interested in video recording of colonoscopy procedure

Colonoscopy is operator-dependent and substantial numbers of pre-cancerous polyps are missed during colonoscopy. Colonoscopies are often poorly documented, with only a few still photographs taken of anatomic landmarks and abnormal findings.

5 Feb 2010

Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

Postmenopausal women undergoing combination hormone therapy at increased risk of heart disease: WHI confirms

Certain patients with IBD at increased risk of developing colorectal cancer: AGA's new guidelines

Research roundup: Bundled payments, PTSD incidence, cost of treating immigrants

PAN to provide co-payment assistance for medications to underinsured patients through five new funds

HDC signs agreement to receive clinical specimens for colon cancer molecular diagnostic test

Medicinal chemistry paper related to the discovery of CUDC-101 published

Insight into mechanism H. pylori uses to evade the immune system

Study provides new data about potential risk of gastric cancer in patients with intestinal metaplasia

Study explores link between HBV genotype C and liver cirrhosis

Study shows lactobacillus is effective in improving H. pylori-infected diseases

Data provide key information about epigenetic profiles for gastric cancer

Johns Hopkins Hospital initiates Phase I trial with Neogenix's NPC-1C

IgM/IgG ratio is useful in diagnosing primary biliary cirrhosis

Insurer to take new role in assessing cancer treatments

Racial disparities continue in U.S. cancer screening practices

Combination of blueberries and probiotics protects against intestinal disorders

Study may provide new intervention strategies for esophageal adenocarcinoma

Study suggests environmental factors play a significant role in the etiology of Crohn's disease

Endoscopic surveillance could be an appropriate strategy for subepithelial lesions

Survey finds majority of patients are interested in video recording of colonoscopy procedure

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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