Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

Impact of BRCA1 mRNA expression on survival of patients breast and colorectal cancer

Oncotarget published "Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients" which reported that LMNB2 is a chromatin remodeling protein that also plays a role in eukaryotic cell proliferation by organizing the nuclear membrane during mitosis.

13 Oct 2021

Research provides insights on colorectal cancers’ immunotherapy resistance

Immune checkpoint inhibitors, which unleash the immune response against tumor cells, have revolutionized cancer treatment; however, the medications aren't effective in a large number of patients, including those with colorectal cancer.

11 Oct 2021

Novel peptide-drug conjugate enhances the efficacy of immunotherapy in preclinical cancer models

A peptide-drug conjugate that targets the acidic environment of cancer cells enhanced the efficacy of immune checkpoint inhibitors in preclinical cancer models, according to results presented at the AACR-NCI-EORTC Virtual International Conference on Molecular Targets and Cancer Therapeutics, held October 7-10, 2021.

7 Oct 2021

NRG Oncology launches highly anticipated colorectal cancer prevention study

Today, NRG Oncology activated the highly anticipated colorectal cancer prevention trial, FORTE, NRG-CC005. FORTE (Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps) is a large, randomized trial of surveillance colonoscopy for participants with a first-time diagnosis of 1 or 2 small benign polyps, called adenomas.

6 Oct 2021

Novel scoring tools developed for predicting risk of colon cancer and precancerous polyps

Researchers have created novel scoring tools for predicting actual risk of colon cancer and advanced precancerous polyps for patients at average for the disease.

5 Oct 2021

Research shows 40% decline in colorectal cancer diagnoses during COVID-19 pandemic

The number of colorectal cancer (CRC) cases diagnosed fell dramatically by 40% in a year during the COVID-19 pandemic, new research presented today at UEG Week Virtual 2021 has shown.

4 Oct 2021

Research finds possible connection between bacteria and bowel cancer

New research from RCSI University of Medicine and Health Sciences has found a possible relationship between the presence of a specific type of bacteria found in tumors and the spread of bowel cancer.

1 Oct 2021

Research shows dramatic decline in colorectal cancer diagnoses during the pandemic

The number of colorectal cancer cases diagnosed fell dramatically by 40% in a year during the COVID-19 pandemic, new research presented today at UEG Week Virtual 2021 has shown.

1 Oct 2021

$94 million PCORI funding to support the next phase of PCORnet and new colorectal cancer study in older adults

The Patient-Centered Outcomes Research Institute Board of Governors today approved $61.3 million for a slate of several infrastructure projects that will support the activities of eight Clinical Research Networks to implement the next phase of PCORnet, the National Patient-Centered Clinical Research Network.

29 Sep 2021

Researchers detect two types of RNA base modifications simultaneously using a quantum sequencer

After a gene is transcribed into RNA, modifications can occur to the subunits or "bases" that make up the RNA molecule, which can affect its structure and function. The study of these changes is known as "epitranscriptomics." These base modifications can occur to most types of RNA molecules, including microRNAs.

29 Sep 2021

Researchers compare transcriptomic and cytokine responses of colorectal cancer cells

Oncotarget published "Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells" which reported that there was an increase in IL-8 by oxaliplatin and increase in ferritin by cisplatin which may contribute to cancer cell survival.

29 Sep 2021

Research provides the basis for an additional novel immunotherapy for multiple myeloma patients

Oncotarget published "Multipeptide stimulated PBMCs generate TEM/TCM for adoptive cell therapy in multiple myeloma" which reported that Multiple Myeloma patients suffer disease relapse due to the development of therapeutic resistance. Increasing evidence suggests that immunotherapeutic strategies can provide durable responses.

29 Sep 2021

Doubling excise duties could prevent alcohol-attributable cancers

In a recent modeling study, scientists at Technische Universität Dresden have examined the impact of increasing taxes on alcoholic beverages on alcohol-attributable cancers in the World Health Organization (WHO) European Region.

22 Sep 2021

Hispanic Americans have a higher risk of preventable infection-related cancers, report shows

A new report shows that although Hispanic men and women in the continental United States and Hawaii have 25% to 30% lower overall cancer incidence and mortality than non-Hispanic Whites, they continue to have a higher risk of potentially preventable, infection-related cancers, including approximately two-fold higher rates of liver and stomach cancers.

21 Sep 2021

Artificial intelligence predicts the risk of metastatic relapse in breast cancer patients

The RACE AI study conducted by Gustave Roussy and the startup Owkin, as part of the AI for Health Challenge organized by the Ile-de-France Region in 2019, was presented as a proffered paper at ESMO.

21 Sep 2021

Researchers reveal a mechanism of SHP2-mediated tumor immunosuppression

Colorectal cancer (CRC), a malignant tumor worldwide consists of microsatellite instability (MSI) and stable (MSS) phenotypes. Although SHP2 is a hopeful target for cancer therapy, its relationship with innate immunosuppression remains elusive. To address that, the authors of this article performed single-cell RNA sequencing to explore the role of SHP2 in all cell types of tumor microenvironment (TME) from murine MC38 xenografts.

21 Sep 2021

Increased presence of certain bacteria in the gut may indicate colon cancer risk

A study published today in the journal Cell Host & Microbe reported that the increased presence of certain bacteria in a gut biome indicates a greater likelihood that colon polyps will become cancerous.

18 Sep 2021

MS patients diagnosed with colorectal cancer may have shorter survival times, study finds

People with multiple sclerosis (MS) who are diagnosed with colorectal cancer may be at a higher risk of dying from cancer or other causes over the next six months to one year than people with colorectal cancer who do not have MS, according to a study published in the September 15, 2021, online issue of Neurology, the medical journal of the American Academy of Neurology.

16 Sep 2021

Colorectal Cancer Project launches to improve understanding of the disease and accelerate research

Count Me In, a nonprofit cancer research initiative, is inviting all patients across the United States and Canada who have ever been diagnosed with colorectal cancer to participate in research and help drive new discoveries related to this disease.

14 Sep 2021

Researchers discover new pathway that makes drugs less effective in bowel cancer patients

Leading scientists at the University of Birmingham have discovered a previously unknown pathway that prevents specific drugs from working in patients with bowel cancer.

14 Sep 2021

Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

Impact of BRCA1 mRNA expression on survival of patients breast and colorectal cancer

Research provides insights on colorectal cancers’ immunotherapy resistance

Novel peptide-drug conjugate enhances the efficacy of immunotherapy in preclinical cancer models

NRG Oncology launches highly anticipated colorectal cancer prevention study

Novel scoring tools developed for predicting risk of colon cancer and precancerous polyps

Research shows 40% decline in colorectal cancer diagnoses during COVID-19 pandemic

Research finds possible connection between bacteria and bowel cancer

Research shows dramatic decline in colorectal cancer diagnoses during the pandemic

$94 million PCORI funding to support the next phase of PCORnet and new colorectal cancer study in older adults

Researchers detect two types of RNA base modifications simultaneously using a quantum sequencer

Researchers compare transcriptomic and cytokine responses of colorectal cancer cells

Research provides the basis for an additional novel immunotherapy for multiple myeloma patients

Doubling excise duties could prevent alcohol-attributable cancers

Hispanic Americans have a higher risk of preventable infection-related cancers, report shows

Artificial intelligence predicts the risk of metastatic relapse in breast cancer patients

Researchers reveal a mechanism of SHP2-mediated tumor immunosuppression

Increased presence of certain bacteria in the gut may indicate colon cancer risk

MS patients diagnosed with colorectal cancer may have shorter survival times, study finds

Colorectal Cancer Project launches to improve understanding of the disease and accelerate research

Researchers discover new pathway that makes drugs less effective in bowel cancer patients

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

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