Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

Bionomics, Merck extend collaboration to develop drug candidates for treatment of chronic and neuropathic pain

Bionomics Limited, a biopharmaceutical company focused on the discovery and development of innovative therapeutics for the treatment of diseases of the central nervous system (CNS) and cancer, today announced that it has extended its strategic collaboration with Merck & Co., Inc., Kenilworth NJ., (known as MSD outside the United States and Canada) for the discovery and development of drug candidates for the treatment of chronic and neuropathic pain.

8 Oct 2015

Targeting protein used by tumors to help detect food supplies could restrict cancerous cells' ability to grow

Oxford University researchers have identified a protein used by tumours to help them detect food supplies. Initial studies show that targeting the protein could restrict cancerous cells' ability to grow.

6 Oct 2015

Advanced targeted therapies dominate treatment pipeline for colorectal cancer, finds Frost & Sullivan

A vast number and variety of remedies are steadily joining the treatment pipeline for colorectal cancer. High incidence of the disease, unmet clinical needs, and huge commercial potential are attracting drug developers to the market.

1 Oct 2015

Clinical trial data from Array BioPharma's binimetinib and encorafenib presented at ECC 2015

Clinical trial results from Array BioPharma's wholly-owned MEK inhibitor, binimetinib, and BRAF inhibitor, encorafenib, were presented this weekend at the European Society of Medical Oncology's annual European Cancer Conference (ECC). At the meeting, preliminary data were shared from both a Phase 2 combination trial of binimetinib and encorafenib in BRAF-mutant melanoma patients (LOGIC2) and a Phase 1b/2 combination trial of binimetinib and ribociclib (Novartis, LEE011), a CDK4/6 inhibitor in NRAS-mutant melanoma patients.

28 Sep 2015

Study may lead to new insights on use of aspirin in GI cancer

Aspirin improves survival in patients with tumours situated throughout the gastrointestinal (GI) tract, results from a large study in The Netherlands show. This is the first time that survival data from patients with tumours in different GI locations have been analysed at the same time; previously, only one type of cancer, usually colorectal, was studied.

28 Sep 2015

FDA approves LONSURF for treatment of patients with metastatic colorectal cancer

Taiho Oncology, Inc. (U.S.), a subsidiary of Taiho Pharmaceutical Co., Ltd. (Japan), today announced that the U.S. Food and Drug Administration approved LONSURF (trifluridine and tipiracil), formerly known as TAS-102, for the treatment of patients with metastatic colorectal cancer (mCRC) who have been previously treated with fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, an anti-VEGF biological therapy, and if RAS wild-type, an anti-EGFR therapy.

22 Sep 2015

VolitionRx's NuQ blood test receives CE Mark approval for detection of colorectal cancer

VolitionRx Limited today announced the Company's first CE Mark for its blood-based diagnostic assay, NuQ X001S, for detection of colorectal cancer. The NuQ test utilizes the Company's proprietary Nucleosomics technology platform, which identifies and analyses fragments of chromosomes, called nucleosomes, circulating within the blood for the presence of epigenetic cancer signals.

22 Sep 2015

Bionomics’ BNC210 Phase 1 trial for anxiety and depression meets primary endpoint

Bionomics Limited, a biopharmaceutical company focused on the discovery and development of innovative therapeutics for the treatment of diseases of the central nervous system (CNS) and cancer, today reported positive data from the completed Phase 1 multiple ascending dose, placebo controlled clinical trial of BNC210, an orally administered negative allosteric modulator of the alpha-7 nicotinic acetylcholine receptor (alpha-7 receptor) being developed for the treatment of anxiety and depression.

16 Sep 2015

EORTC and ESSO project provides opportunity to do prospective study on liver metastasis surgery

Is it possible to cure patients with unresectable colorectal liver metastases? Are complex surgeries safe for patients with extensive metastatic disease? How can we monitor and improve the quality of these surgical strategies? How can we improve surgical care for patients through research?

15 Sep 2015

Combining epigenetic drugs with immunotherapies may provide additional clinical benefit to cancer patients

Recent data suggest that epigenetic therapies are likely to provide additional clinical benefit to cancer patients when rationally combined with immunotherapeutic drugs, according to a review published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

15 Sep 2015

Patient position helps increase effectiveness of colonoscopy for CRC screening

Having patients lie on their left side while the right side of their colon is being examined can result in more polyps being found, thus increasing the effectiveness of colonoscopy for colorectal cancer (CRC) screening, according to a study in the September issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy (ASGE).

14 Sep 2015

Novel long non-coding RNA has potential to stymie growth of tumor cells in colon cancer

Genetics researchers from Case Western Reserve School of Medicine have identified a novel long non-coding RNA (lncRNA), dubbed DACOR1, that has the potential to stymie the growth of tumor cells in the second-most deadly form of cancer in the U.S. — colorectal cancer.

14 Sep 2015

Tadpole Endoscope improves diagnostic procedures for various cancers

Engineers have developed a new medical device aimed at improving diagnostic procedures for various cancers: the Tadpole Endoscope (TE).

14 Sep 2015

Researchers identify new epigenetic markers for colorectal cancer

Researchers at Nanjing University, China, found new epigenetic markers for colorectal cancer which may offer a new approach for treatment.

14 Sep 2015

New risk assessment scoring system may help physicians select screening tests for colorectal cancer

Researchers at the Regenstrief Institute and the Indiana University School of Medicine have developed a new risk assessment scoring system that could help physicians judge which patients can forgo invasive colonoscopy testing for cancer screening and which should receive the test.

11 Sep 2015

New AGA guideline recommends colorectal cancer patients to undergo tumor test for Lynch syndrome

All colorectal cancer patients should undergo tumor testing to see if they carry Lynch syndrome, the most common inherited cause of colorectal cancer, according to a new guideline published in Gastroenterology, the official journal of the American Gastroenterological Association.

11 Sep 2015

Researchers use nanopore technology for early detection of colorectal and lung cancers

Using tiny "nanopore" scanners that can detect individual DNA molecules, Professor Amit Meller and colleagues are on the hunt for biological markers in cancer cells that may help clinicians diagnose colorectal and lung cancers at their earliest stages.

10 Sep 2015

ICU-related mortality may explain variations in cancer outcomes

A Scottish population-based study has characterised the incidence of critical illness resulting in admission to an intensive care unit during the first 2 years after a cancer diagnosis.

9 Sep 2015

Using whole genomes data to improve bowel cancer diagnosis: an interview with Professor Ian Tomlinson

The project aims to sequence the specified 100,000 genomes from two types of patients: first, those who may have rare inherited diseases caused by unknown or unidentified genes; and second, people with one of several types of cancer, including colorectal cancer.

9 Sep 2015

Penns' Abramson Cancer Center rated as 'exceptional' by NCI

The University of Pennsylvania's Abramson Cancer Center (ACC) has received an "exceptional" rating by the National Cancer Institute during an extensive peer-review process for its five-year competitive research support grant. The rating is the highest possible for an NCI cancer center.

9 Sep 2015

Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

Bionomics, Merck extend collaboration to develop drug candidates for treatment of chronic and neuropathic pain

Targeting protein used by tumors to help detect food supplies could restrict cancerous cells' ability to grow

Advanced targeted therapies dominate treatment pipeline for colorectal cancer, finds Frost & Sullivan

Clinical trial data from Array BioPharma's binimetinib and encorafenib presented at ECC 2015

Study may lead to new insights on use of aspirin in GI cancer

FDA approves LONSURF for treatment of patients with metastatic colorectal cancer

VolitionRx's NuQ blood test receives CE Mark approval for detection of colorectal cancer

Bionomics’ BNC210 Phase 1 trial for anxiety and depression meets primary endpoint

EORTC and ESSO project provides opportunity to do prospective study on liver metastasis surgery

Combining epigenetic drugs with immunotherapies may provide additional clinical benefit to cancer patients

Patient position helps increase effectiveness of colonoscopy for CRC screening

Novel long non-coding RNA has potential to stymie growth of tumor cells in colon cancer

Tadpole Endoscope improves diagnostic procedures for various cancers

Researchers identify new epigenetic markers for colorectal cancer

New risk assessment scoring system may help physicians select screening tests for colorectal cancer

New AGA guideline recommends colorectal cancer patients to undergo tumor test for Lynch syndrome

Researchers use nanopore technology for early detection of colorectal and lung cancers

ICU-related mortality may explain variations in cancer outcomes

Using whole genomes data to improve bowel cancer diagnosis: an interview with Professor Ian Tomlinson

Penns' Abramson Cancer Center rated as 'exceptional' by NCI

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

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