Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

New insights into γδ T cells could improve treatment for colorectal cancer

The most common form of colorectal cancer, microsatellite-stable colorectal cancer (MSS CRC), can currently only be treated to a limited extent with modern immunotherapies.

27 Aug 2024

The significance of CHEK2 variants in cancer risk assessment

A new editorial was published in Oncotarget's Volume 15 on July 10, 2024, entitled, "Genotype matters: Personalized screening recommendations for germline CHEK2 variants."

27 Aug 2024

Total neoadjuvant therapy shows promising results in routine care for advanced rectal cancer

Research on a modified TNT regimen for high-risk rectal cancer reveals similar complete response rates and lower toxicity compared to traditional approaches.

26 Aug 2024

Advances in sequencing uncover rare genetic variants in colorectal cancer

Colorectal cancer (CRC) presents a significant health challenge, especially with rare genetic variations complicating treatment.

23 Aug 2024

New treatment for rectal cancer offers hope in avoiding surgery

A new treatment for locally advanced rectal cancer shows favorable results in that surgery can sometimes be avoided completely.

23 Aug 2024

Advances in endoscopic treatment for inflammatory bowel disease complications

Inflammatory bowel diseases (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), are chronic inflammatory conditions affecting the gastrointestinal tract.

23 Aug 2024

Vitamin D deficiency linked to higher cancer mortality

Researchers review how vitamin D deficiency affects the risk of cancer-related mortality.

20 Aug 2024

The gut barrier plays key role in colorectal cancer prognosis

A new review was published in Oncotarget's Volume 15 on August 14, 2024, entitled, "The gut barrier as a gatekeeper in colorectal cancer treatment."

19 Aug 2024

New research gives unprecedented view of colorectal cancer genetic makeup

Researchers provided a comprehensive genomic characterization of colorectal carcinoma, a type of cancer that starts in the colon or rectum, through whole-genome sequencing of 2,023 samples, identifying novel driver genes, molecular subgroups, and potential clinical implications.

15 Aug 2024

Diet-derived molecules identified as main drivers of young-onset colorectal cancer risk

A new Cleveland Clinic study has identified diet-derived molecules called metabolites as main drivers of young-onset colorectal cancer risk, especially those associated with red and processed meat.

14 Aug 2024

Largest multi-omics study identifies new genetic landscapes in colorectal cancer

The Institute of Intelligent Medical Research (IIMR) of BGI Genomics, in collaboration with Sweden's Uppsala University, has published the largest multi-omics study of colorectal cancer (CRC) to date.

13 Aug 2024

New perspectives on targeting BRAF alterations in cancer

A new research perspective was published in Oncotarget's Volume 15 on July 16, 2024, entitled, "Targeting the multifaceted BRAF in cancer: New directions."

12 Aug 2024

Can how often you eat meat raise your risk of colorectal cancer?

Study shows that high processed meat intake significantly increases colorectal neoplasm risk, with effects equivalent to a 19 percentile increase in genetic risk scores, while red meat consumption shows no significant association.

11 Aug 2024

Zebrafish model reveals how BCG vaccine triggers immune response in bladder cancer

Using zebrafish "Avatars", an animal model developed by the Cancer Development and Innate Immune Evasion lab at the Champalimaud Foundation (CF), led by Rita Fior, Mayra Martínez-López – a former PhD student at the lab now working at the Universidad de las Américas in Quito, Ecuador – and colleagues studied the initial steps of the Bacillus Calmette-Guérin (BCG) vaccine's action on bladder cancer cells.

8 Aug 2024

Study finds aspirin reduces colon cancer risk, with benefits varying by lifestyle factors

Aspirin can reduce colorectal cancer risk, but its effectiveness varies based on lifestyle factors such as diet, BMI, and smoking. Personalized recommendations are crucial to identify those who would benefit most from aspirin use.

7 Aug 2024

Reduced folate intake enhances metabolic plasticity in aged mice

Folate fortification of staple foods has long been practiced in many countries.

6 Aug 2024

Cancer screening costs exceed $40 billion annually in the United States

A modeling study estimates cancer screening costs in the United States exceed $40 billion annually, highlighting the need for policy prioritization to enhance equitable access. The study emphasizes that recommended screenings significantly reduce cancer-specific mortality and can be cost-effective.

5 Aug 2024