Coronary Artery Disease

Coronary artery disease is the most common type of heart disease and the leading cause of death worldwide. It occurs when the arteries that supply blood to the heart become narrowed or blocked by a buildup of "plaque" - cholesterol or other fatty deposits that build on the inner wall of the artery.

What is Coronary Artery Disease?

Coronary artery disease is another term used for atherosclerotic heart disease, a condition caused by a narrowing, hardening and furring of the walls of the coronary arteries.

Coronary Artery Disease Treatment

Coronary Artery Disease Characteristics

Coronary Artery Disease Angina

Coronary Artery Disease and Omega-3 Fatty Acids

Coronary Artery Disease Pathophysiology

Coronary Artery Disease Prevention

Coronary Artery Disease Preventive Diets

Coronary Artery Disease Risk Factors

Coronary Artery Disease and Aspirin

Latest Coronary Artery Disease News and Research

Mendelian randomization study reveals opposing roles for IL6 and IL6R in long-term mortality

A new research paper was published in Volume 18 of Aging-US on February 6, 2026, titled "Causal effects of inflammation on long-term mortality: a Mendelian randomization study."

27 Feb 2026

Rethinking cardiovascular risk assessment in women

Less artery-clogging plaque in women's arteries did not appear to protect them from heart disease compared to men, according to a study published in Circulation: Cardiovascular Imaging, an American Heart Association journal.

23 Feb 2026

Sex differences in coronary plaque burden and cardiovascular event risk revealed

Coronary artery disease (CAD) is the most common cause of death globally. In CAD, plaques composed of cholesterol, fats, calcium and other compounds accumulate and create obstructions in the coronary vessels that supply blood to the heart.

23 Feb 2026

Predictive power of C-reactive protein shifts based on cirrhosis or coronary disease

A new study reveals that the predictive power of key inflammatory markers, such as C-reactive protein, shifts fundamentally depending on whether a patient suffers from cirrhosis or acute/chronic coronary disease.

18 Feb 2026

New AI-based approach detects fatty deposits inside coronary arteries using OCT images

Researchers have developed a new artificial intelligence-based approach for detecting fatty deposits inside coronary arteries using optical coherence tomography (OCT) images.

17 Feb 2026

Redefining cardiovascular care for women

Cardiovascular disease (CVD) remains the leading cause of death for women across the globe, yet significant progress has been made in prevention, diagnosis and management thanks to more sex-specific research, as noted in a special Go Red for Women issue of Circulation, the American Heart Association's flagship, peer-reviewed scientific journal, published today.

17 Feb 2026

Study explores how reversible RNA editing could transform future cardiovascular medicine

This mini-review synthesises evidence showing that adenosine-to-inosine RNA editing plays an important regulatory role in cardiovascular development, cellular homeostasis, and disease biology. It highlights emerging links between dysregulated RNA editing and cardiovascular conditions while outlining biomarker potential and reversible RNA-editing therapeutic strategies that remain under investigation.

15 Feb 2026

4D-printed vascular stents expand naturally at body temperature

Cardiovascular diseases constitute a major global health concern. Various complications that affect normal blood flow in arteries and veins, such as stroke, blood clot formation in veins, blood vessel rupture, and coronary artery disease, often require vascular treatments.

6 Feb 2026

Age shapes long-term outcomes after multi-arterial CABG strategies

A late-breaking study drawing on more than 15 years of national outcomes data from the STS Adult Cardiac Surgery Database (ACSD) suggests that the two most commonly used multi-arterial coronary artery bypass grafting (CABG) strategies-bilateral internal thoracic artery (BITA) and single internal thoracic artery plus radial artery (SITA+RA)-offer comparable long-term survival overall, with important differences emerging by patient age.

31 Jan 2026

Antiplatelet medications linked to worse outcomes in people hospitalized with a brain bleed

Analysis of hospital registry data found that people who were hospitalized due to bleeding in the brain and who had taken multiple antiplatelet medications, or medications stronger than aspirin, were more likely to die before leaving the hospital compared to those not taking any antiplatelet medication, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2026.

29 Jan 2026

TGM2 as a novel biomarker for acute myocardial infarction and prognosis in acute coronary syndrome

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Transglutaminase 2 (TGM2) has been implicated in various health conditions, yet its role in acute coronary syndrome (ACS) remains poorly characterized in clinical settings.

21 Jan 2026

A single immune protein may help explain why kidney and heart disease often develop together

This review synthesizes clinical, genetic, and mechanistic evidence showing that suPAR and related uPAR fragments are strongly associated with kidney, cardiovascular, and metabolic disease risk. It highlights suPAR as a stable biomarker of innate immune activation with potential pathogenic roles, while underscoring major gaps in assay standardization and therapeutic validation.

6 Jan 2026

Women may derive greater long-term benefits from coronary artery bypass grafting compared with stents

Women with severe coronary heart disease causing narrowing or blockages in the arteries may derive greater long-term benefits from coronary artery bypass grafting compared with percutaneous coronary intervention, also known as stenting, according to a large study by Weill Cornell Medicine investigators.

22 Dec 2025

Couples-based programs boost heart-healthy behaviors

Research highlights the need for couple-based interventions in heart disease to focus on emotional support and relationship quality for better health outcomes.

18 Dec 2025

AI enables rapid detection of coronary microvascular dysfunction from standard EKGs

Doctors may soon be able to diagnose an elusive form of heart disease within seconds by using an AI model developed at University of Michigan, according to a recent study.

16 Dec 2025

E-cigarette use is linked to higher heart attack risk, especially in former smokers

This systematic review and meta-analysis examined whether electronic cigarette use is associated with myocardial infarction and stroke, synthesizing evidence from 12 observational studies. The analysis found higher odds of myocardial infarction among e-cigarette users, particularly former smokers, while no significant associations were observed among exclusive never-smokers.

14 Dec 2025

Increased epicardial fat volume linked to greater myocardial injury after infarction

Increased volume of epicardial adipose tissue, detected by cardiovascular imaging, was found to be associated with greater myocardial injury after a myocardial infarction.

12 Dec 2025

AI-based tool may help personalize the treatment of patients with reduced coronary blood flow

Reduced coronary blood flow, measured with an artificial intelligence-based imaging tool, predicted future cardiovascular events in patients with suspected stable coronary artery disease.

11 Dec 2025

Uterine fibroids linked to higher long-term heart disease risk in women

Long-term heart disease risk in women diagnosed with uterine fibroids was more than 80% higher than in women without fibroids, according to new independent research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

10 Dec 2025

Long-term air pollution exposure linked to more advanced coronary artery disease

Long-term exposure to common air pollutants is associated with more advanced coronary artery disease-with notable differences between women and men-according to a large-scale study of more than 11,000 adults being presented today at the annual meeting of the Radiological Society of North America (RSNA).

4 Dec 2025

Coronary Artery Disease

Overview

Coronary Artery Disease Treatment

Coronary Artery Disease Characteristics

Coronary Artery Disease Angina

Feature Articles

Coronary Artery Disease and Omega-3 Fatty Acids

Coronary Artery Disease Pathophysiology

Coronary Artery Disease Prevention

Coronary Artery Disease Preventive Diets

Coronary Artery Disease Risk Factors

Coronary Artery Disease and Aspirin

Latest Coronary Artery Disease News and Research

Mendelian randomization study reveals opposing roles for IL6 and IL6R in long-term mortality

Rethinking cardiovascular risk assessment in women

Sex differences in coronary plaque burden and cardiovascular event risk revealed

Predictive power of C-reactive protein shifts based on cirrhosis or coronary disease

New AI-based approach detects fatty deposits inside coronary arteries using OCT images

Redefining cardiovascular care for women

Study explores how reversible RNA editing could transform future cardiovascular medicine

4D-printed vascular stents expand naturally at body temperature

Age shapes long-term outcomes after multi-arterial CABG strategies

Antiplatelet medications linked to worse outcomes in people hospitalized with a brain bleed

TGM2 as a novel biomarker for acute myocardial infarction and prognosis in acute coronary syndrome

A single immune protein may help explain why kidney and heart disease often develop together

Women may derive greater long-term benefits from coronary artery bypass grafting compared with stents

Couples-based programs boost heart-healthy behaviors

AI enables rapid detection of coronary microvascular dysfunction from standard EKGs

E-cigarette use is linked to higher heart attack risk, especially in former smokers

Increased epicardial fat volume linked to greater myocardial injury after infarction

AI-based tool may help personalize the treatment of patients with reduced coronary blood flow

Uterine fibroids linked to higher long-term heart disease risk in women

Long-term air pollution exposure linked to more advanced coronary artery disease

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Coronary Artery Disease

Overview

Feature Articles

Coronary Artery Disease and Omega-3 Fatty Acids

Coronary Artery Disease Pathophysiology

Coronary Artery Disease Prevention

Coronary Artery Disease Preventive Diets

Coronary Artery Disease Risk Factors

Coronary Artery Disease and Aspirin

Latest Coronary Artery Disease News and Research

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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