Coronary Artery Disease

Coronary artery disease is the most common type of heart disease and the leading cause of death worldwide. It occurs when the arteries that supply blood to the heart become narrowed or blocked by a buildup of "plaque" - cholesterol or other fatty deposits that build on the inner wall of the artery.

What is Coronary Artery Disease?

Coronary artery disease is another term used for atherosclerotic heart disease, a condition caused by a narrowing, hardening and furring of the walls of the coronary arteries.

Coronary Artery Disease Pathophysiology

Coronary Artery Disease Angina

Coronary Artery Disease Risk Factors

Coronary Artery Disease Prevention

Coronary Artery Disease Preventive Diets

Coronary Artery Disease and Aspirin

Coronary Artery Disease and Omega-3 Fatty Acids

Coronary Artery Disease Characteristics

Coronary Artery Disease Treatment

Latest Coronary Artery Disease News and Research

Study reveals new genetic explanation for dilated cardiomyopathy

A potentially life-changing heart condition, dilated cardiomyopathy, can be caused by the cumulative influence of hundreds or thousands of genes and not just by a single "aberrant" genetic variant, as was previously thought, finds a new study led by researchers at UCL (University College London), Imperial College London and the MRC Laboratory of Medical Sciences.

21 Nov 2024

Study reveals variability in polygenic risk scores for predicting heart disease

Polygenic risk scores (PRSs) are a cutting-edge tool in genetics, combining information from genetic markers across the genome to estimate a person's risk of developing certain diseases, such as coronary artery disease (CAD).

19 Nov 2024

Proactively screening diabetes patients for heart disease does not improve long-term survival

While coronary heart disease and diabetes are often seen in the same patients, a diagnosis of diabetes does not necessarily mean that patients also have coronary heart disease, according to a new study from researchers at Intermountain Health in Salt Lake City.

18 Nov 2024

Study suggests beta-blockers may elevate depression symptoms in post-MI patients

In MI patients with preserved heart function, beta-blockers are linked to higher depressive symptoms, indicating a need for careful mental health assessment.

13 Nov 2024

Study finds no benefit of routine orbital atherectomy in cardiac stenting

Routine use of an orbital atherectomy device to remove calcium from severely blocked coronary arteries before patients undergo cardiac stenting procedures does not improve outcomes, a Mount Sinai-led study has found.

29 Oct 2024

Research highlights importance of quality improvement programs in stroke care

New research published this month shows the key role quality improvement programs play in ensuring hospitals can adequately fight one of the biggest public health threats facing our country: stroke.

24 Oct 2024

Ultra-rare gene variants drive coronary artery disease risk in European ancestry

Researchers found that ultra-rare genetic variants play a significant role in the heritability of coronary artery disease (CAD), particularly in individuals of European ancestry. These variants, especially those altering proteins or regulating genes in heart cells, pose higher risks than common variants.

13 Oct 2024

The long-term cardiac impact of COVID-19

Study shows that severe COVID-19 elevates the long-term risk of major adverse cardiac events (MACE), making it comparable to coronary artery disease. It also highlights a genetic interaction with ABO blood type, influencing cardiovascular outcomes.

13 Oct 2024

SCAI publishes comprehensive guidelines for STEMI treatment

The Society for Cardiovascular Angiography & Interventions (SCAI) is pleased to announce the publication of the Expert Consensus Statement on the Management of Patients with STEMI Referred for Primary PCI.

12 Oct 2024

COVID-19 survivors at greater risk for heart attack, stroke and death

A history of COVID-19 can double the risk of heart attack, stroke or death according to new research led by Cleveland Clinic and the University of Southern California.

9 Oct 2024

COVID-19 found to increase heart attack and stroke risks

An analysis of data in the UK Biobank has found that COVID-19 infection may increase the risk of heart attack, stroke and death from any cause for up to three years for people with and without cardiovascular disease, according to new research published today in the American Heart Association's peer-reviewed journal Arteriosclerosis, Thrombosis and Vascular Biology (ATVB).

9 Oct 2024

FDA approves new PET imaging agent for coronary artery disease

The U.S. Food and Drug Administration (FDA) has approved flurpiridaz F-18 (Flyrcado; GE Healthcare), a first-of-its-kind positron emission tomography (PET) imaging agent, for use in adult patients with known or suspected coronary artery disease (CAD).

1 Oct 2024

Women remain underserved in cardiovascular disease treatment despite advances

Women in the UK, and elsewhere, are still missing out on vital treatment for their No 1 killer-;cardiovascular disease-;despite significant progress in the medical management of heart disease and stroke, concludes a consensus statement published online in the journal Heart.

24 Sep 2024

New guidelines for cardiovascular management in noncardiac surgery released

The 2024 guideline for cardiovascular management of adults undergoing noncardiac surgery reflects a decade of updates and new evidence since the guideline's last release in 2014.

24 Sep 2024

Medicare coverage for obesity drug raises questions

Millions of older Americans with obesity could potentially get Medicare's help with the hefty price of a weight-loss medication in order to reduce their high risk of heart problems.

23 Sep 2024

New model identifies cancer patients at high risk for ER visits during clinical trials

Investigators from the SWOG Cancer Research Network have developed and validated a risk prediction model for identifying which patients with advanced cancer who are enrolled to clinical trials are at highest risk for unplanned emergency room (ER) visits and hospital stays.

23 Sep 2024

Cardiovascular disease pathways associated with psoriasis, but not other immune-mediated diseases

A genetic connection between cardiovascular disease and psoriasis highlights shared inflammatory pathways, emphasizing the need for cardiovascular monitoring.

19 Sep 2024

PlaqueTec and RxCelerate collaborate on early phase drug discovery for coronary artery disease

PlaqueTec, a company identifying endotype-specific biomarkers to advance precision medicine for coronary artery disease (CAD), and RxCelerate, a leading international out-sourced drug discovery and development service provider, today announced the successful completion of a collaboration to assess small molecules identified from an initial cheminformatics drug screen in a bespoke cell-based assay developed by RxCelerate on one of PlaqueTec’s targets discovered in pilot studies.

18 Sep 2024

Socioeconomic disparities in coronary artery disease deaths linked to unhealthy behaviors

Lower socioeconomic status is associated with higher rates of death from coronary artery disease compared to higher socioeconomic status, and more than half of the disparities can be explained by four unhealthy behaviors.

17 Sep 2024

Study reveals tropical oils' dual impact: Vital vitamins and dangerous side effects

A comprehensive review of tropical oils reveals their health benefits and risks, highlighting coconut and palm oil's impact on nutrition and disease prevention.

16 Sep 2024