Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Air pollution exposure takes a heavy toll on gut bacteria, boosting risk of chronic illnesses

Breathing dirty air takes a heavy toll on gut bacteria, boosting risk of obesity, diabetes, gastrointestinal disorders and other chronic illnesses, new University of Colorado Boulder research suggests.

11 Mar 2020

Immunosuppressive therapy does not increase risk of vulvar or vaginal cancer in women with IBD

In a new retrospective study, researchers found that the use of immunosuppressive therapy does not increase the occurrence or recurrence of vulvar or vaginal cancer in women with inflammatory bowel disease (IBD).

11 Mar 2020

Aging and competition for nutrients determine changes in gut bacteria

Two studies with surprising discoveries: in the elderly, the bacterium E. coli evolves in a way that can become potentially pathogenic and increase the risk of disease and, according to data obtained in another study, the metabolism of the same bacterium present in the microbiota evolves differently if it is alone or accompanied by other bacteria.

11 Mar 2020

Inhibiting specific protein could make radiation therapy for colon cancer more effective

Researchers at Washington University School of Medicine in St. Louis appear to have discovered a way to make radiation therapy for colorectal cancer more effective by inhibiting a protein found in cancer cells in the gut.

3 Mar 2020

Visceral fat gives signal to the brain that damages cognition

Excessive weight around our middle gives our brain's resident immune cells heavy exposure to a signal that turns them against us, setting in motion a crescendo of inflammation that damages cognition, scientists say.

3 Mar 2020

New discovery will change our understanding of bile production

Forget what you know about bile because that's about to change, thanks to a new discovery made by Michigan State University and published in the current issue of Nature.

26 Feb 2020

Ulcerative colitis and a missing microbe in the gut

Ulcerative colitis is a seriously debilitating inflammatory disease of the bowel leading to crippling symptoms that can affect the quality of life severely. Researchers from Stanford University School of Medicine have found in a new study that a missing microbe could be linked to this condition. The study was published today in the latest issue of the journal Cell Host & Microbe.

25 Feb 2020

Georgia State researcher receives $1.67 million federal grant to study gut immunity

Dr. Tim Denning, professor and associate director of the Institute for Biomedical Sciences at Georgia State University, has received a four-year, $1.67 million federal grant to study how an immunological pathway influences inflammatory signaling in the intestine that can lead to chronic human diseases such as inflammatory bowel disease.

9 Feb 2020

Study reveals how the gut's protective mechanisms ramp up with food intake

A new study has revealed how the gut's protective mechanisms ramp up significantly with food intake, and at times of the day when mealtimes are anticipated based on regular eating habits.

29 Jan 2020

Study advances the understanding of capillary regression

Many diseases arise from abnormalities in our capillaries, tiny exquisitely branching blood vessel networks that play a critical role in tissue health.

29 Jan 2020

Study sheds light on mechanisms that underlie a rare genetic condition

A team of researchers at CHU Sainte-Justine and Université de Montréal has shed light on the mechanisms that underlie a rare genetic condition by creating the first cellular model of the disease.

22 Jan 2020

Study reveals new mechanism involved in the pathogenesis of IBD

Inflammatory bowel disease is a category of refractory inflammatory disease, of which ulcerative colitis and Crohn's disease are the main types.

21 Jan 2020

Bile acids could also play a role in immunity and inflammation

Could bile acids--the fat-dissolving juices churned out by the liver and gallbladder--also play a role in immunity and inflammation?

3 Jan 2020

Links between most human diseases and genetics are shaky at best

In most cases, your genes have less than five per cent to do with your risk of developing a particular disease, according to new research by University of Alberta scientists.

20 Dec 2019

Gastroesophageal reflux disease may affect nearly a third of U.S. adults every week

Gastroesophageal reflux disease (GERD), a digestive disorder that causes hearburn and other uncomfortable symptoms, may affect nearly a third of U.S. adults each week, and most of those who take certain popular medications for it still have symptoms, according to a new Cedars-Sinai study.

19 Dec 2019

Study: Blocking IL1α protein decreases severity of inflammation in Crohn's disease

Investigators at the Case Western Reserve University School of Medicine discovered that blocking interleukin-1α (IL1α), a protein that controls inflammation in the gut, markedly decreases the severity of intestinal inflammation in a mouse model of Crohn's disease (CD).

17 Dec 2019

Scientists develop an approach to vaccinate against gut inflammation

Inflammatory bowel disease (IBD) is an umbrella term that describes many disorders that involve chronic inflammation of the digestive tract, including ulcerative colitis and Crohn's disease. These conditions are tied to certain alternations in the gut flora.

12 Dec 2019

Dendritic cells could lead to better treatments for persistent infections, cancer

Autoimmune disorders such as rheumatoid arthritis, psoriasis, and Crohn's disease plague tens of millions of Americans and are the result of the body's immune system, whose role is to fight against disease-causing pathogens, turning against itself.

12 Dec 2019

New method reveals how microbial communities function in our bodies

In the last decade, scientists have made tremendous progress in understanding that groups of bacteria and viruses that naturally coexist throughout the human body play an important role in some vital functions like digestion, metabolism and even fighting off diseases. But understanding just how they do it remains a question.

11 Dec 2019

New system enables real-time observations of individual cells in the colon

Biomedical engineers at Duke University have developed a system that allows for real-time observations of individual cells in the colon of a living mouse.

11 Dec 2019