Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Multiple sclerosis drug Tysabri could be back on the market later in the year

The drug Tysabri which was approved by the Food and Drug Administration (FDA) for the treatment of multiple sclerosis in November 2004, was taken off the market in late February, after two cases of progressive multifocal leukoencephalopathy, or PML, appeared in patients given the drug during clinical trials.

9 Jun 2005

Stimulating innate immunity helps ease Crohn's disease symptoms

Like throwing oil on a fire or prescribing a high cholesterol diet for heart patients, gastroenterologists traditionally have believed that it would not be a good idea to stoke up the body's immune system to treat Crohn's disease.

26 May 2005

No link between MMR jab and Crohn's disease

A research paper published in 1998, which claimed the MMR jab was in some way linked to autism and Crohn's disease, the inflammatory bowel disease, caused MMR vaccination numbers to fall across the country.

12 May 2005

Color doppler sonography speeds detection of necrotizing enterocolitis in premature infants

Measuring blood flow to a newborn's intestines using a special form of ultrasound can help radiologists identify a life-threatening complication in a serious bowel disease, according to a study in the May issue of the journal Radiology.

26 Apr 2005

Discovery of gene STAT6(B) may lead to new treatments for inflammatory diseases

In a paper featured in Proceedings of the National Academy of Science (PNAS), researchers from Boston University School of Dental Medicine report the discovery of a new gene, STAT6(B), that helps regulate production of the potentially deadly tumor necrosis factor alpha (TNF-alpha) cytokine.

28 Mar 2005

Vital molecular step in cell migration

A vital molecular step in cell migration, the movement of cells within the body during growth, tissue repair and the body's immune response to invading pathogens, has been demonstrated by researchers in the University of California, San Diego (UCSD) School of Medicine.

28 Mar 2005

Calcium and vitamin D treatment alone can improve bone mineral density in Crohn's patients

According to a study published today in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology, the addition of popular bone building drugs to calcium and vitamin D therapy to treat bone loss associated with Crohn's disease is not beneficial.

1 Feb 2005

Biochip for detection of inflammatory bowel disease

At the III International Symposium on Advanced Therapy for Chronic Inflammatory Bowel Disease, held in Madrid, the biotechnological company, Progenika, presented a DNA-chip the purpose of which is the optimisation of the diagnosis, prognosis and treatment of patients with inflammatory bowel disease (Crohn’s disease and Ulcerous Colitis).

26 Jan 2005

Monoclonal antibody therapeutics to fill vacuum left by ineffective conventional therapies

Currently, the limited efficacy of conventional therapies, especially in the case of several oncology and autoimmune and inflammatory disorders (AIID), is creating the need for safe and effective treatment alternatives.

25 Jan 2005

Small is beautiful in the medical world

Small is beautiful in the medical world. And being able to give European industry the edge in a nearly €200 billion worldwide biomedical market is what drives a consortium of EU-backed partners to make and market smaller, cheaper and better biomedical devices and innovative new applications.

19 Jan 2005

New findings clarify the role of NOD2, a key molecular player in Crohn's Disease

This week, researchers report new findings that clarify the role of NOD2, a key molecular player in Crohn's Disease, in the cellular signaling pathways that control inflammatory responses. NOD2's clinical relevance is clear from the fact that it is encoded by a Crohn's Disease susceptibility gene.

28 Dec 2004

Parasitic worms, or helminths, may be an effective treatment for Crohn's disease

Helminths, such as roundworms and threadworms, are rare in developed countries, where rates of Crohn's disease are high. But in developing countries where corresponding rates of the disease are low, many people carry these parasitic worms.

13 Dec 2004

FDA approval of Tysabri, for the treatment of multiple sclerosis

Biogen and Elan Corporation have announced that the U.S. Food and Drug Administration (FDA) has approved Tysabri (natalizumab), as treatment for relapsing forms of multiple sclerosis (MS) to reduce the frequency of clinical relapses.

24 Nov 2004

Abbott's investigational anti-interleukin-12 fully human monoclonal antibody in Crohn's disease study

Results of a Phase II study of Abbott's ABT-874, a fully human anti-interleukin-12 (IL-12) monoclonal antibody, will appear tomorrow in the New England Journal of Medicine citing treatment with ABT-874 shows differences in response and remission in patients with active Crohn's disease compared to placebo, in one arm of the study.

10 Nov 2004

New studies demonstrate efficacy of novel Lipoxin analog in laboratory models of Crohn's disease

Berlex announced today that new laboratory results demonstrate that its modified version of the naturally occurring lipoxin molecule exerts potent anti-inflammatory and immunomodulatory effects in Crohn's disease in vivo models and may provide a promising new oral treatment.

9 Nov 2004

Analysis shows Remicade reduces pain associated with Crohn's disease

According to a new sub-analysis from the ACCENT I (A Crohn's disease Clinical trial Evaluating infliximab in a New long-term Treatment regimen) trial patients who received a three-dose induction regimen of Remicade experienced a significantly greater reduction in pain as assessed by four different pain questions after ten weeks, compared with patients who received a single dose of Remicade.

2 Nov 2004

New research points to potential new treatments for sickle cell disease

New research from the University of North Carolina at Chapel Hill reveals why red blood cells from people with sickle cell disease are stickier than healthy red cells, pointing the way to potential new treatments for sickle cell disease.

12 Oct 2004

New oral gel used instead of injection to deliver drugs

Scientists in India have developed a new gel that is taken orally and is capable of delivering drugs to manage diseases often requiring an injection.

20 Sep 2004

Crohn’s disease may be caused by same bacterium that causes Paratuberculosis or Johne’s disease in cattle, sheep, and goats

A study in this week’s issue of THE LANCET suggests that Crohn’s disease may be caused by Mycobacterium avium subspecies paratuberculosis (MAP), the same bacterium that causes a similar intestinal disorder (known as Paratuberculosis or Johne’s disease) in cattle, sheep, and goats.

17 Sep 2004

Genetically modified bacterium as remedy for intestinal diseases

Researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) at Ghent University are joining the fight against chronic intestinal disease with a genetically modified bacterium (Lactococcus lactis).

14 Sep 2004

Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Multiple sclerosis drug Tysabri could be back on the market later in the year

Stimulating innate immunity helps ease Crohn's disease symptoms

No link between MMR jab and Crohn's disease

Color doppler sonography speeds detection of necrotizing enterocolitis in premature infants

Discovery of gene STAT6(B) may lead to new treatments for inflammatory diseases

Vital molecular step in cell migration

Calcium and vitamin D treatment alone can improve bone mineral density in Crohn's patients

Biochip for detection of inflammatory bowel disease

Monoclonal antibody therapeutics to fill vacuum left by ineffective conventional therapies

Small is beautiful in the medical world

New findings clarify the role of NOD2, a key molecular player in Crohn's Disease

Parasitic worms, or helminths, may be an effective treatment for Crohn's disease

FDA approval of Tysabri, for the treatment of multiple sclerosis

Abbott's investigational anti-interleukin-12 fully human monoclonal antibody in Crohn's disease study

New studies demonstrate efficacy of novel Lipoxin analog in laboratory models of Crohn's disease

Analysis shows Remicade reduces pain associated with Crohn's disease

New research points to potential new treatments for sickle cell disease

New oral gel used instead of injection to deliver drugs

Crohn’s disease may be caused by same bacterium that causes Paratuberculosis or Johne’s disease in cattle, sheep, and goats

Genetically modified bacterium as remedy for intestinal diseases

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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