Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

Human lungs rejected for transplant can be recovered using cross-circulation with pigs

A new experiment by researchers at the Columbia Engineering and Vanderbilt University may have the solution to this long-standing problem. The team revived and repaired the damaged lungs by cross-circulation support of the whole lungs outside the body using the circulatory system with that of a living pig.

14 Jul 2020

Vav3 protein promotes cystic fibrosis, shows study

Cystic fibrosis, one of the most common genetic diseases in Switzerland, causes severe respiratory and digestive disorders.

14 Jul 2020

Repurposed drug for acute lung injury in COVID-19

Now, a new study addresses the possible use of an FDA-approved monoclonal antibody, called fostamatinib, a spleen tyrosine kinase inhibitor (SYK), to reduce the levels of mucin-1, a molecule associated with acute lung injury and acute respiratory distress syndrome (ARDS). People who have severe COVID-19 disease may develop ARDS.

2 Jul 2020

Chemist develops new drug to treat type 2 diabetes without undesired side effects

Syracuse University chemistry professor Dr. Robert P. Doyle has developed a new drug lead to treat type 2 diabetes in millions of patients who are seeking to better control their blood sugar without the common side effects of nausea, vomiting, and in select cases, undesired weight loss.

23 Jun 2020

Study identifies new gene variants tied to type-2 diabetes

After examining the genes of more than 200,000 people all over the world who have type-2 diabetes, researchers from the Perelman School of Medicine at the University of Pennsylvania and the Veterans Health Administration's Corporal Michael J. Crescenz Veterans Affairs Medical Center found hundreds of genetic variants never before linked to the disease.

23 Jun 2020

Researchers develop a simple tool for making mouse models of COVID-19

Until there are effective treatments or vaccines, the COVID-19 pandemic will remain a significant threat to public health and economies around the world. A major hurdle to developing and testing new anti-viral therapies and vaccines for COVID-19 is the lack of good, widely available animal models of the disease.

16 Jun 2020

Novel disease may lead to a better understanding of cystic fibrosis

Cystic fibrosis is the most frequent severe inherited disorder worldwide. Every year, hundreds of families are confronted with this diagnosis - and to date, there is no cure for this disease that mainly affects the respiratory system.

5 Jun 2020

Genome-based monitoring of multi-resistant pathogen can help improve infection control

S. maltophilia strains occur in several natural and human associated ecosystems. The bacterium was long regarded as relatively unproblematic but is now considered to be one of the most feared hospital pathogens, as it frequently causes infections and is resistant to a number of antibiotics.

15 May 2020

ACMG: Technical standard on CFTR variant testing updated

It has been nearly two decades since the American College of Medical Genetics and Genomics, together with the American College of Obstetricians and Gynecologists, made the landmark recommendation that cystic fibrosis (CF) become the first target of pan-ethnic universal carrier screening, with ACMG identifying a core panel of 23 pathogenic variants to be tested.

14 May 2020

New antibiotic fights drug-resistant bacteria without notable toxic side-effects

Through serendipity, researchers at the University of Pittsburgh Graduate School of Public Health considerably reduced the toxicity of a potential antibiotic against the most feared drug-resistant bacteria, while also improving its stability in fighting infections.

4 May 2020

Long-lasting, low toxicity antimicrobial peptide fights 'superbug' lung infections

Researchers considerably reduced the toxicity of a potential antibiotic against the most feared drug-resistant bacteria.

1 May 2020

New insights into self-management plans for children with chronic conditions

With stressed hospital services, and concerns about the spread of COVID-19, experts are reminding carers of children and young people of the importance of adhering to supported chronic condition self-management plans from the safety of their home.

22 Apr 2020

Are overactive immune cells causing COVID-19-related deaths?

While the COVID-19 pandemic is devastating many regions, the world over, a new paper published in the Journal of Experimental Medicine in April 2020 describes the possibility that the critical or very severe cases of COVID-19 are due to the production of neutrophil extracellular traps (NET) due to hyperactivated immune cells.

16 Apr 2020

Tuberculosis bacteria facilitate their spread by producing a molecule that triggers cough

The bacteria that cause the deadly lung disease tuberculosis appear to facilitate their own spread by producing a molecule that triggers cough, a new study led by UTSW researchers shows.

5 Mar 2020

Treatments for rare diseases affecting children are increasing, study suggests

The number of treatments for rare diseases affecting children has increased, a new study suggests. But federal incentives intended to encourage drug development for rare conditions are being used more often to expand the use of existing drugs rather than for creating new ones.

3 Mar 2020

SFU researchers help discover potential new drug to kill superbugs

Researchers in Simon Fraser University's Brinkman Laboratory are collaborating with U.S. researchers to test a new drug that can kill a wide range of superbugs - including some bacteria now resistant to all common antibiotics.

3 Mar 2020

Link discovered between number of antibiotic prescriptions and higher risk of hospital admissions

Epidemiologists at The University of Manchester have discovered an association between the number of prescriptions for antibiotics and a higher risk of hospital admissions.

2 Mar 2020

New discovery will change our understanding of bile production

Forget what you know about bile because that's about to change, thanks to a new discovery made by Michigan State University and published in the current issue of Nature.

26 Feb 2020

Researchers discover glial cells that control stress response, extend lifespan in worms

While many of us worry about proteins aggregating in our brains as we age and potentially causing Alzheimer's disease or other types of neurodegeneration, we may not realize that some of the same proteins are aggregating in our muscles, setting us up for muscle atrophy in old age.

23 Feb 2020

Researchers develop novel therapy to combat antibiotic-resistant superbug infections

There may be a solution on the horizon to combating superbug infections resistant to antibiotics. The tenacious bacteria and fungi sicken more than 2.8 million people and lead to more than 35,000 deaths in the United States each year.

20 Feb 2020

Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

Human lungs rejected for transplant can be recovered using cross-circulation with pigs

Vav3 protein promotes cystic fibrosis, shows study

Repurposed drug for acute lung injury in COVID-19

Chemist develops new drug to treat type 2 diabetes without undesired side effects

Study identifies new gene variants tied to type-2 diabetes

Researchers develop a simple tool for making mouse models of COVID-19

Novel disease may lead to a better understanding of cystic fibrosis

Genome-based monitoring of multi-resistant pathogen can help improve infection control

ACMG: Technical standard on CFTR variant testing updated

New antibiotic fights drug-resistant bacteria without notable toxic side-effects

Long-lasting, low toxicity antimicrobial peptide fights 'superbug' lung infections

New insights into self-management plans for children with chronic conditions

Are overactive immune cells causing COVID-19-related deaths?

Tuberculosis bacteria facilitate their spread by producing a molecule that triggers cough

Treatments for rare diseases affecting children are increasing, study suggests

SFU researchers help discover potential new drug to kill superbugs

Link discovered between number of antibiotic prescriptions and higher risk of hospital admissions

New discovery will change our understanding of bile production

Researchers discover glial cells that control stress response, extend lifespan in worms

Researchers develop novel therapy to combat antibiotic-resistant superbug infections

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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