Cytokines News and Research

Latest Cytokines News and Research

Researchers identify genes linked to death from sepsis in mice

Sepsis is a life-threatening condition that occurs when the body's immune response to infection spirals out of control.

23 Jul 2019

Single-cell encapsulation technology can protect transplanted MSCs from immune attack

Bone marrow transplants of hematopoietic stem cells have become standard treatment for a host of conditions including cancers of the blood and lymphatic systems, sickle cell anemia, inherited metabolic disorders, and radiation damage.

16 Jul 2019

Special blood test may predict relapse risk for breast cancer patients

A special blood test may one day predict if a newly diagnosed breast cancer patient will likely relapse years later, a City of Hope study suggests.

9 Jul 2019

Long-term follow-up of childhood cancer survivors is essential to maintain bone health

Advances in the treatment of children and adolescents with cancer have led to substantial improvements in survival, with a 5-year survival rate of childhood cancer close to 80%.

3 Jul 2019

Using popular anticonvulsant drug to thwart inflammation

Serious conditions, including sepsis, stem from inflammation in the body, and there is a lack of effective medication for sepsis.

2 Jul 2019

Large doses of traditional chemotherapy drug spur immune system attack on cancer cells

More than 60 years ago, British physician Denis Parsons Burkitt and his associates achieved one of the signal successes in cancer medicine when they cured children in sub-Saharan Africa with a form of lymphoma by treating them with high doses of the chemotherapy drug cyclophosphamide.

2 Jul 2019

New target identified for treatment of idiopathic pulmonary fibrosis

An article published in Experimental Biology and Medicine (Volume 244, Issue 9, June 2019) (https://journals.sagepub.com/doi/pdf/10.1177/1535370219843827) identifies a new target for the treatment of idiopathic pulmonary fibrosis.

29 Jun 2019

Study provides new insight into development of asthma

Researchers at Karolinska Institutet in Sweden have studied which genes are expressed in overactive immune cells in mice with asthma-like inflammation of the airways.

27 Jun 2019

First safe, reliable, noninvasive way to monitor rheumatoid arthritis

A first-in-human Phase 1/Phase II study demonstrates that intravenous administration of the radiopharmaceutical imaging agent technetium-99m (99mTc) tilmanocept promises to be a safe, well-tolerated, noninvasive means of monitoring rheumatoid arthritis disease activity.

24 Jun 2019

Complement system shown to remove dead cells in retinitis pigmentosa, contradicting previous research

Researchers have found that the complement system seems to protect against retinal degeneration in retinitis pigmentosa.

18 Jun 2019

Researchers find way to reinvigorate exhausted immune cells and stop cancer

The human immune system relies on a delicate balance of finely tuned cell types that keep germs and cancerous cells in check.

18 Jun 2019

Research highlights potential targets to help fight Crohn's disease

Affecting around 115,000 people in the UK alone, Crohn's disease is a lifelong condition which sees parts of the digestive system become inflamed.

17 Jun 2019

Urinary DKK3 can improve prediction of AKI

A new renal biomarker was presented at the ERA-EDTA Congress last year: that shows that urinary DKK3 might help to identify patients who are at risk of progressive chronic kidney disease.

17 Jun 2019

Virus employs powerful strategy to inhibit natural killer cell function

The virus responsible for chickenpox and shingles employs a powerful strategy of immune evasion, inhibiting the ability of natural killer cells to destroy infected cells and produce molecules that help control viral infection, according to a study published June 13 in the open-access journal PLOS Pathogens by Allison Abendroth of the Discipline of Infectious Diseases and Immunology in the Charles Perkins Centre at the University of Sydney, and colleagues.

From PLOS ONE 14 Jun 2019

Pre-pregnancy maternal obesity may affect growth of breastfeeding infants

A pioneering new study suggests that babies born to obese or overweight women fail to grow properly during breastfeeding.

14 Jun 2019

Disease-modifying therapy for Alport syndrome still remains an unmet need

Alport syndrome is a hereditary type IV collagen disease that leads to progressive proteinuria, renal fibrosis, and kidney failure.

13 Jun 2019

Fibrinogen a key player in health and disease, says new study

A new study from the University of Alberta demonstrated that the blood clotting protein called fibrinogen also regulates MMP-2, an enzyme involved in immunity and in clot formation inside blood vessels. Prolonged MMP-2 inhibition could potentially produce a deficiency state with severe consequences.

12 Jun 2019

Researchers identify macrophages' pathway to nurture PTEN-deficient glioblastoma

A common genetic deficiency empowers glioblastoma to broadcast a molecular message to the wrong type of immune cell, summoning macrophages that protect and nurture the brain tumor instead of attacking it, researchers at The University of Texas MD Anderson Cancer Center report in Cancer Cell.

11 Jun 2019

Chronic inflammation removes motivation by reducing dopamine in the brain

Why do we feel listless when we are recovering from an illness? The answer is, apparently, that low-grade chronic inflammation interferes with the dopaminergic signaling system in the brain that motivates us to do things.

5 Jun 2019

Scientific discovery may lead to a treatment for lupus

A team of scientists has uncovered the structure of a regulatory complex that is involved in the release of cytokines and can be inhibited to treat lupus.

31 May 2019