Cytokines News and Research

Latest Cytokines News and Research

Magnetic nanoparticles could enhance the efficacy of cancer immunotherapy

Boosting the function of natural killer cells with magnetic nanoparticles could make cancer immunotherapy more efficient.

6 Aug 2021

Activation of NLRP3 inflammasome by the N protein of SARS-CoV-2 to induce hyperinflammation

A new study has revealed the mechanism by which the SARS-CoV-2 N protein activates NLRP3 inflammasomes to induce hyperinflammation.

5 Aug 2021

Immune system signaling molecule promotes the production of energy-burning 'beige fat'

An immune signal promotes the production of energy-burning "beige fat," according to a new study publishing August 5th in the open-access journal PLOS Biology by Zhonghan Yang of Sun Yat-Sen University, Guangzhou, China, and colleagues.

5 Aug 2021

Vaccinia-based COVID-19 vaccines confer immunity in hamster model

In a paper recently uploaded to the preprint server bioRxiv* by Kulkarni et al. (August 3, 2021), the potential of vaccinia virus-based vaccines expressing the full-length SARS-CoV-2 spike protein is examined in mice and Syrian hamsters. The findings report that the vaccine generates high titers of neutralizing antibodies with good activity towards SARS-CoV-2 variants of concern.

5 Aug 2021

How does the mRNA/lipid nanoparticle platform promote protective adaptive immunity against SARS-CoV-2?

Modified mRNA combined with lipid nanoparticles may be beneficial in boosting adaptive immunity against SARS-CoV-2. Research led by Botond Z. Igyártó from Thomas Jefferson University’s Department of Microbiology and Immunology in Pennsylvania recently found that the lipid nanoparticles induce protective adaptive immune responses with antibody titers against lethal doses of the virus.

5 Aug 2021

The role of natural killer cells in the fight against coronavirus infection

This study proposes a mathematical framework to analyze the effect of the viruses on type I interferon (IFN-I) signaling, which is part of the innate immune response. IFN-I brings about natural killer cell activation, which in turn causes the activation of macrophages.

4 Aug 2021

Study looks at potent phytocompounds from Himalayan herbs to treat COVID-19

Considering the antiviral activity of medicinal herbs, a new study published in the journal Current Pharmacology Reports focuses on the identification of potent phytochemicals from Himalayan herbs, namely, Rheum emodi, Thymus serpyllum, and Artemisia annua, for the treatment of COVID-19.

1 Aug 2021

Phase 1/2 trial results for Nanocovax, protein subunit SARS-CoV-2 vaccine from Vietnam

Nanocovax is a protein subunit vaccine that contains the full-length spike stabilized by the addition of two prolines

29 Jul 2021

Streptococcus pneumoniae modulates host immunity to SARS-CoV-2

Scientists from the UK and US have recently investigated immunological consequences of secondary Streptococcus pneumoniae (S. pneumoniae) infection in coronavirus disease 2019 (COVID-19) patients.

29 Jul 2021

Study examines the role of programmed cell death ligands in skin immune responses

T cells are a crucial part of the human adaptive immune system. In response to a foreign invader in the body, various subsets of T cells are responsible for several functions that include killing infected cells and secreting signaling molecules called cytokines that tell other immune cells where to go and what to do.

29 Jul 2021

How do people with post acute sequelae of COVID-19 react to SARS-CoV-2 vaccines?

A new study focuses on the impact of vaccines on the changes in the symptoms in the PASC group.

27 Jul 2021

T cells are not critical for recovery of primates from acute COVID-19 infections, study reveals

New research conducted in monkeys reveals that T cells are not critical for the recovery of primates from acute COVID-19 infections.

27 Jul 2021

Study shows inhalable nanocatchers can protect lung cells against SARS-CoV-2

Inhalable nanocatchers that contain hACE2 have been recently developed by a group of researchers, providing a plethora of potential benefits in comparison to existing treatments against COVID-19.

27 Jul 2021

Researchers develop new exosome formulation to deliver VEGF antibodies for synergistic therapy

Researchers from the Institute of Process Engineering of the Chinese Academy of Sciences, Beijing Chaoyang Hospital and the University of Queensland have developed a new formulation based on regulatory T-cell exosomes (rEXS) to deliver vascular endothelial growth factor (VEGF) antibodies for choroidal neovascularization therapy.

26 Jul 2021

Clinical trials during a pandemic – lessons from COVID-19

In this interview, Dr. Benedicte Roquebert, Dr. Stephanie Haim-Boukobza and Dr. Souad Mehlal discuss how COVID-19 has resulted in new ways to think about clinical trials during a pandemic.

From Cerba Research 23 Jul 2021

Can prior human seasonal coronavirus antibody response patterns predict SARS-CoV-2 inhibition?

A new study, recently released as a preprint on the medRxiv* server, reports the intriguing finding that the cross-neutralizing antibodies elicited by human seasonal coronaviruses (sCoVs) show varying ability to prevent binding between the SARS-CoV-2 spike antigen and its cognate receptor, the angiotensin-converting enzyme 2 (ACE2).

22 Jul 2021

Human tissue xenografts in murine models for the study of SARS-CoV-2

Severe COVID-19 is associated with massive dysregulation of the host immune response, resulting in inflammation and the condition known as a cytokine storm. For the most part, however, the virus is barely noticeable or only mild among the young and healthy, suggesting that the route and intensity of an immune response could determine the severity of the disease.

20 Jul 2021

IgA deficiency results in substantial intestinal inflammation, study reveals

While researchers have known for years that immunoglobulin A (IgA) is important for gut health, it has remained unclear exactly what role it plays in preventing infection and disease. But now, researchers from Japan have found that eliminating IgA disrupts the balance of the intestinal ecosystem, making it susceptible to disease.

20 Jul 2021

How SARS-CoV-2 infects the brain

While there is no official explanation on how SARS-CoV-2 travels to the brain, a new review published in the journal Fluids and Barriers of the CNS concluded that there is insufficient evidence on COVID-induced neurological problems coming from a direct invasion of SARS-CoV-2 into the brain.

20 Jul 2021

Study reveals pathological mechanism and treatment strategy of pre-engraftment syndrome

The research team led by Prof. WEI Haiming and Prof. TIAN Zhigang from Division of Life Sciences and Medicine, University of Science and Technology of China of the Chinese Academy of Sciences, collaborating with the research group led by Prof. SUN Zimin from the First Affiliated Hospital of USTC revealed the pathological mechanism of severe pre-engraftment syndrome (PES) after umbilical cord blood transplantation, not only providing a treatment strategy for patients with PES, but significantly guiding for further improvement in the curative effect of unrelated cord blood transplantation (UCBT).

19 Jul 2021

Cytokines News and Research

Latest Cytokines News and Research

Magnetic nanoparticles could enhance the efficacy of cancer immunotherapy

Activation of NLRP3 inflammasome by the N protein of SARS-CoV-2 to induce hyperinflammation

Immune system signaling molecule promotes the production of energy-burning 'beige fat'

Vaccinia-based COVID-19 vaccines confer immunity in hamster model

How does the mRNA/lipid nanoparticle platform promote protective adaptive immunity against SARS-CoV-2?

The role of natural killer cells in the fight against coronavirus infection

Study looks at potent phytocompounds from Himalayan herbs to treat COVID-19

Phase 1/2 trial results for Nanocovax, protein subunit SARS-CoV-2 vaccine from Vietnam

Streptococcus pneumoniae modulates host immunity to SARS-CoV-2

Study examines the role of programmed cell death ligands in skin immune responses

How do people with post acute sequelae of COVID-19 react to SARS-CoV-2 vaccines?

T cells are not critical for recovery of primates from acute COVID-19 infections, study reveals

Study shows inhalable nanocatchers can protect lung cells against SARS-CoV-2

Researchers develop new exosome formulation to deliver VEGF antibodies for synergistic therapy

Clinical trials during a pandemic – lessons from COVID-19

Can prior human seasonal coronavirus antibody response patterns predict SARS-CoV-2 inhibition?

Human tissue xenografts in murine models for the study of SARS-CoV-2

IgA deficiency results in substantial intestinal inflammation, study reveals

How SARS-CoV-2 infects the brain

Study reveals pathological mechanism and treatment strategy of pre-engraftment syndrome

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

Cytokines News and Research

Latest Cytokines News and Research

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

Newsletters you may be interested in