Diarrhea News and Research

Latest Diarrhea News and Research

High-powered magnets continue to be a safety risk to children

An increasing number of incident reports to the U.S. Consumer Product Safety Commission (CPSC) indicate that high-powered magnets continue to be a safety risk to children. From toddlers to teens, children are swallowing these magnets and the consequences are severe.

10 Nov 2011

Faster, more sensitive test to detect ciguatera poisoning

Scientists are reporting development of a fast, reliable new test that could help people avoid a terrible type of food poisoning that comes from eating fish tainted with a difficult-to-detect toxin from marine algae growing in warm waters. The report appears in ACS' journal Analytical Chemistry.

10 Nov 2011

Three common scales are not accurate predictors of severe dehydration in children

A physician team from Rhode Island Hospital led a study to evaluate the accuracy of the commonly used dehydration scales as they apply to children in a low-income country. Based on their experience in Rwanda, the researchers determined that none of the three scales were accurate predictors of severe dehydration in children with diarrhea and/or vomiting.

9 Nov 2011

Celgene to initiate apremilast Phase III placebo-controlled trial for ankylosing spondylitis

Celgene International Sàrl, a subsidiary of Celgene Corporation, today announced data from a Phase II study of apremilast, its investigational oral immunomodulatory compound, in patients with ankylosing spondylitis (AS) were presented at the American College of Rheumatology Scientific Meeting in Chicago, IL.

9 Nov 2011

Salix third quarter total product revenue increases 81% to $146.2 million

Salix Pharmaceuticals, Ltd. today announced financial and operating results for the third quarter ended September 30, 2011 and other business updates.

9 Nov 2011

Amylin and Lilly terminate exenatide alliance, resolve litigation

Amylin Pharmaceuticals, Inc. and Eli Lilly and Company today announced an agreement to terminate their alliance for exenatide and resolve the outstanding litigation between the companies.

9 Nov 2011

FDA accepts Genentech's vismodegib NDA for review

Curis, Inc., a drug development company seeking to develop next generation targeted small molecule drug candidates for cancer treatment, today announced that the U.S. Food and Drug Administration (FDA) has accepted and filed for review Genentech's new drug application (NDA) for vismodegib for the treatment of adults with advanced basal cell carcinoma (BCC) for whom surgery is considered inappropriate.

9 Nov 2011

Salix enters definitive agreement to acquire Oceana Therapeutics

Salix Pharmaceuticals, Ltd. and Oceana Therapeutics, LLC today announced that they have entered into a definitive agreement whereby Salix will acquire all of the outstanding stock of Oceana Therapeutics, Inc., a privately-held global provider of gastroenterology and urology therapeutics, for $300 million in cash.

8 Nov 2011

New results from BioCryst's BCX4208 Phase 2b gout study

BioCryst Pharmaceuticals, Inc. presents new results from its Phase 2b randomized, double-blind, dose-response study of BCX4208 in patients with gout who have failed to reach the clinically important serum uric acid (sUA) goal of <6 mg/dL on allopurinol alone.

8 Nov 2011

Private sector companies should contribute to GAVI Matching Fund

The GAVI Alliance has "announced a major new initiative aimed at engaging private sector leaders: the GAVI Matching Fund," through which "the British Government's Department for International Development (DFID) and the Bill & Melinda Gates Foundation will provide a 100 percent match of contributions to GAVI from corporations and foundations as well as their customers, members and employees," Bill Roedy, former CEO of MTV Networks and a GAVI Alliance envoy, writes in a post on the Huffington Post's "Impact" blog.

8 Nov 2011

Bristol-Myers Squibb receives FDA approval for Erbitux to treat head and neck cancer

The U.S. Food and Drug Administration today approved Erbitux (cetuximab) for use with chemotherapy to treat patients with late-stage (metastatic) head and neck cancer.

8 Nov 2011

IntraPace receives CE Mark for new gastric stimulation/food sensing lead

IntraPace, Inc. announced today that it has received CE Mark for the LGL102, a new gastric stimulation/food sensing lead designed to work with the innovative abiliti system, an implantable weight loss management system.

7 Nov 2011

Vertex announces positive interim data from INCIVEK Phase 2 combination trial on HIV, HCV

Vertex Pharmaceuticals Incorporated today announced positive interim results from an ongoing Phase 2 study designed to evaluate the safety and tolerability of INCIVEK (telaprevir) tablets in combination with pegylated-interferon and ribavirin in people who are co-infected with chronic genotype 1 hepatitis C (HCV) and human immunodeficiency virus.

7 Nov 2011

Human Genome Sciences to present abstracts regarding BENLYSTA, SLE at ACR/ARHP meeting

Human Genome Sciences, Inc. announced today that several abstracts related to BENLYSTA (belimumab) and systemic lupus erythematosus will be presented at the annual meeting of the American College of Rheumatology/ Association of Rheumatology Health Professionals, being held in Chicago, IL from November 4 to November 9, 2011.

5 Nov 2011

Common gut pathogen increases activity of SMO gene and causes colon tumors

Working with lab cultures and mice, Johns Hopkins scientists have found that a strain of the common gut pathogen Bacteroides fragilis causes colon inflammation and increases activity of a gene called spermine oxidase (SMO) in the intestine.

5 Nov 2011

AMAG reports third quarter total revenues of $17.6 million

AMAG Pharmaceuticals, Inc. today reported unaudited consolidated financial results for the third quarter ended September 30, 2011.

4 Nov 2011

Longer looks: A doctor's dilemma on C-sections; apology for a death sparked a hospital's change

I was the obstetrician on hospital duty that Sunday morning, so I introduced myself and learned that the patient, pregnant with her first child, wished to have as few interventions as possible. Respecting her desire, we decided to reevaluate her in a few hours to see how her labor had progressed. But would she get her wish? ... the odds were greater than 1 in 4 that this woman would end up not with the natural delivery she wanted, but with a surgical delivery in one of the two operating rooms down the hall.

4 Nov 2011

Final results from Vertex KALYDECO second of two Phase 3 studies on CF

Vertex Pharmaceuticals Incorporated today announced final results from the ENVISION study, the second of two pivotal Phase 3 studies of KALYDECO, a medicine in development that targets the defective protein that causes cystic fibrosis.

4 Nov 2011

FDA EMDAC votes to recommend approval of Merck's VYTORIN for pre-dialysis CKD

Merck, known as MSD outside the United States and Canada, announced today that the Endocrinologic and Metabolic Drugs Advisory Committee of the U.S. Food and Drug Administration (FDA) unanimously voted to recommend approval of Merck's VYTORIN (ezetimibe/simvastatin) for use in patients with pre-dialysis chronic kidney disease.

3 Nov 2011

Targeted antibiotic safe and effective for irritable bowel syndrome

Among the most commonly used treatments for irritable bowel syndrome - which affects as many as 20 percent of the United States population - a targeted antibiotic was shown to be the safest in a new study by Cedars-Sinai researchers, based on an analysis of 26 large-scale clinical trials.

2 Nov 2011