Endocrinology News and Research

Latest Endocrinology News and Research

Novel genome-analysis strategy to speed search for gene-disease links

University of Washington (UW) researchers have successfully developed a novel genome-analysis strategy for more rapid, lower cost discovery of possible gene-disease links. By saving time and lowering expenses, the approach makes it feasible for scientists to search for disease-causing genes in people with the same inherited disorder but without any family ties to each other.

18 Aug 2009

Synco Bio to manufacture Versartis type 2 diabetes drug candidate

SynCo Bio Partners, a Netherlands based biopharmaceutical contract manufacturer, and Versartis, Inc. today announced a strategic partnership to produce Versartis' lead drug candidate VRS-859, a novel GLP-1 analog for monthly dosing to treat type 2 diabetes Under the agreement, SynCo will further develop the Versartis existing production process for VRS-859 and optimize the manufacturing process to increase yields for the forthcoming cGMP production.

18 Aug 2009

Opinion: Chronic disease in Africa; education can help combat disease; climate change and health; TB vaccine

"An epidemic of chronic, non-communicable diseases such as heart disease, mental illness, cancer, diabetes, and obesity is growing in Africa, a continent still struggling with infectious and nutritional diseases," according to a Boston Globe opinion piece by Michelle Holmes and Shona Dalal.

18 Aug 2009

Scientific studies enough to warrant action on bisphenol A

Scientists, physicians, consumers and environmental health advocates today responded to an FDA staff presentation on progress of their review of bisphenol A (BPA), a synthetic sex hormone linked to cancer, diabetes, heart problems and other illness. Congressmen Henry Waxman and Bart Stupak asked for FDA to review their evaluation of BPA.

17 Aug 2009

Sugar "feeds" tumors

Researchers at Huntsman Cancer Institute at the University of Utah have uncovered new information on the notion that sugar "feeds" tumors. The findings may also have implications for other diseases such as diabetes. The research is published in the journal Proceedings of the National Academy of Sciences.

17 Aug 2009

Aeterna Zentaris announces results from trials of Cetrorelix in benign prostatic hyperplasia

AEterna Zentaris Inc. today reported Phase 3 results for its North American efficacy trial Z-033 and the safety trial Z-041 in benign prostatic hyperplasia (BPH), with its lead endocrinology compound for urology, cetrorelix pamoate. As announced on March 6, 2009, sanofi-aventis U.S. LLC entered into an agreement with AEterna Zentaris for the development, registration and marketing of cetrorelix in BPH for the U.S. market.

17 Aug 2009

Updated, evidence-based guidelines highlight primary care needs of HIV patients

With HIV patients living longer thanks to advances in treatment, the primary care needs of those living with HIV have never been more important. Updated, evidence-based guidelines from the HIV Medicine Association (HIVMA) and the Infectious Diseases Society of America (IDSA) are designed to help providers manage the care of those living with this complex chronic infection.

14 Aug 2009

Scientists create new method to detect genetic causes of complex diseases

Computational biologists at Carnegie Mellon University have developed an analytical technique to detect the multiple genetic variations that contribute to complex disease syndromes such as diabetes, asthma and cancer, which are characterized by multiple clinical and molecular traits.

14 Aug 2009

Tissue scarring key to link between obesity and diabetes

The team, in collaboration with University Hospital Aintree, the University of Warwick and researchers in Sweden, found that people classified as obese and those with pre-diabetes have raised levels of a protein called SPARC, that can cause tissue scarring.

13 Aug 2009

Interleukin Genetics reports Q2 2009 financials

Interleukin Genetics, Inc. (NYSE Amex: ILI) today announced financial and operational results for the second quarter ended June 30, 2009.

13 Aug 2009

A healthy diet helps prevent kidney stones

Researchers have found another reason to eat well: a healthy diet helps prevent kidney stones. Loading up on fruits, vegetables, nuts, low-fat dairy products, and whole grains, while limiting salt, red and processed meats, and sweetened beverages is an effective way to ward off kidney stones, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN).

13 Aug 2009

Scientists grow new blood vessels to combat heart disease

Although open-heart surgery is a frequent treatment for heart disease, it remains extremely dangerous. Now groundbreaking research from Dr. Britta Hardy of Tel Aviv University's Sackler School of Medicine has shown the potential for an injected protein to regrow blood vessels in the human heart ― eliminating the need for risky surgery altogether.

13 Aug 2009

New nutrition practice guidelines for patients with spinal cord injury

The American Dietetic Association has published new evidence-based nutrition practice guidelines for registered dietitians on nutrition care for patients with spinal cord injury.

12 Aug 2009

High-fat diets just as unhealthy in short term as long term

Short-term memory getting worse? Exercise getting harder? Examine your diet. New research published online in The FASEB Journal showed that in less than 10 days of eating a high-fat diet, rats had a decreased ability to exercise and experienced significant short-term memory loss. These results show an important link between what we eat, how we think, and how our bodies perform.

12 Aug 2009

Meal replacements in a medically supervised weight loss program aid weight loss

Meal replacements in a medically supervised weight loss program are successful in facilitating weight loss, according to a new study conducted at the University of Kentucky. The study appears in the August 2009 issue of the Journal of the American Dietetic Association.

12 Aug 2009

Giant pituitary adenoma can be safely removed through nasal route

It’s even worse than being told you have a brain tumor: having a tumor so large, it’s in a category all its own. Giant pituitary adenoma is a so-called “benign” tumor that can cause visual loss and impair many of the body’s most basic functions. But fortunately, even the largest of these giant tumors—which can grow to the size of an egg and invade nearby structures--can be treated effectively using a multimodality approach starting with minimally invasive surgery through the nose, according to a new study at the John Wayne Cancer Institute at Saint John’s Health Center.

12 Aug 2009

Transcript: President Obama Town Hall meeting in New Hampshire

President Barack Obama continued his press for public support of health reform initiatives at what the White House called a "Health Insurance Reform Town Hall" meeting at Portsmouth High School in Portsmouth, New Hampshire.

12 Aug 2009

Researchers respond to concerns about international insulin drug trial

Accumulating safety data from the large, international ORIGIN trial have been reviewed by its independent data monitoring committee, who have concluded that there is no cause for concern.

12 Aug 2009

Aldose reductase inhibition shows promise for asthma

University of Texas Medical Branch at Galveston researchers have found that a single enzyme is apparently critical to most allergen-provoked asthma attacks - and that activity of the enzyme, known as aldose reductase, can be significantly reduced by compounds that have already undergone clinical trials as treatments for complications of diabetes.

11 Aug 2009

High-fat diet affects physical and memory abilities of rats after 9 days

Rats fed a high-fat diet show a stark reduction in their physical endurance and a decline in their cognitive ability after just nine days, a study by Oxford University researchers has shown.

11 Aug 2009