Endocrinology News and Research

Latest Endocrinology News and Research

High levels of glutamate in brain linked to depression, low cognitive function

Researchers at the Joslin Diabetes Center and several other institutions have for the first time linked high levels of glutamate – a neurotransmitter in the brain produced from glucose – in people with type 1 diabetes to symptoms of depression and lower levels of cognitive performance. The findings may lead to a better understanding of the underlying mechanisms of these conditions in people with diabetes.

4 Aug 2009

Elevated cholesterol levels in midlife raises risk of late-life dementia

Elevated cholesterol levels in midlife - even levels considered only borderline elevated - significantly increase the risk of Alzheimer's disease and vascular dementia later in life, according to a new study by researchers at Kaiser Permanente's Division of Research and the University of Kuopio in Finland. The study appears in the journal Dementia & Geriatric Cognitive Disorders.

4 Aug 2009

The extremes of BMI a cause for concern in liver transplantation

A recent study by doctors at the University of Washington explained that patients who are significantly underweight or very severely obese prior to liver transplantation are at increased risk of death following transplantation surgery.

4 Aug 2009

Will emphasis on prevention bring health costs down?

If there is one thing that both parties can agree on in the health overhaul debate, it’s the need to build a health system that promotes prevention rather than just manages disease.

4 Aug 2009

FDA approves Livalo (pitavastatin), a new cholesterol-lowering drug

The U.S. Food and Drug Administration today approved the 4 milligram maximum dose of Livalo (pitavastatin), a drug intended to improve blood cholesterol levels in persons with elevated or abnormal blood cholesterol levels.

3 Aug 2009

Metformin associated with reduced risk of pancreatic cancer in diabetics

The antidiabetic medication metformin is associated with a reduced risk of pancreatic cancer in diabetics, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute. However, other commonly used therapies, such as insulin or insulin secretagogues, may be associated with increased risk for the deadly disease.

3 Aug 2009

FDA approves Onglyza (saxagliptin) for type 2 diabetes

The U.S. Food and Drug Administration has approved Onglyza (saxagliptin), a once-daily tablet to treat Type 2 diabetes in adults. The medication is intended to be used with diet and exercise to control high blood sugar levels.

2 Aug 2009

Health-related quality of life in chronic kidney disease patients

Chronic kidney disease (CKD) can significantly lessen patients' quality of life, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). Certain types of patients - women, diabetics, and those with a history of heart complications - are most affected.

31 Jul 2009

Common food additive lecithin may help control blood lipids and reduce disease risk

Scientists at Washington University School of Medicine in St. Louis have identified a substance in the liver that helps process fat and glucose. That substance is a component of the common food additive lecithin, and researchers speculate it may one day be possible to use lecithin products to control blood lipids and reduce risk for diabetes, hypertension or cardiovascular disease using treatments delivered in food rather than medication.

31 Jul 2009

Short-term complications after bariatric surgery for extreme obesity low

Short-term complications and death rates were low following bariatric surgery to limit the amount of food that can enter the stomach, decrease absorption of food or both, according to the Longitudinal Assessment of Bariatric Surgery (LABS-1). The study was funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health. Results are reported in the July 30 issue of the New England Journal of Medicine.

30 Jul 2009

Primary care gets boost from stimulus money, experiment on 'medical home'

"Secretary of Health and Human Services Kathleen Sebelius announced Tuesday that $200 million will be available for grants, loans, loan repayments and scholarships for the training of some 8,000 health professionals by the end of fiscal 2010," Congressional Quarterly reports.

30 Jul 2009

Deferoxamine could help diabetics heal wounds

A drug used to remove iron from the body could help doctors fight one of diabetes' cruelest complications: poor wound healing, which can lead to amputation of patients' toes, feet and even legs.

28 Jul 2009

Repeated stress signals made in cells with metabolism-associated disease encourage the growth of invading bacteria

Mitochondrial diseases disrupt the power generating machinery within cells and increase a person's susceptibility to bacterial infection, particularly in the lungs or respiratory tract.

28 Jul 2009

System 50 years out of date for chronic illness

Many people with chronic health conditions have more than one disease, which makes caring for them much more complex. Unfortunately, the way our health system is structured now, and the way it is paid for, reflects the health needs our society had about 50 years ago.

27 Jul 2009

Intensive glucose control halves complications of longstanding type 1 diabetes

Near-normal control of glucose beginning as soon as possible after diagnosis would greatly improve the long-term prognosis of type 1 diabetes, concludes a study published in the July 27, 2009, issue of the Archives of Internal Medicine, which updates information about the clinical course of type 1 diabetes.

27 Jul 2009

Obesity expert says rates of severe childhood obesity have tripled

Rates of severe childhood obesity have tripled in the last 25 years, according to a recent study by an obesity expert at Brenner Children's Hospital.

27 Jul 2009

Discovery of key event in prostate cancer progression

A study led by researchers at the Ohio State University Comprehensive Cancer Center and Dana-Farber Cancer Institute reveals how late-stage, hormone-independent prostate tumors gain the ability to grow without need of hormones.

24 Jul 2009

Researchers identify women at risk of gaining excessive weight with Depo-Provera

Researchers at the University of Texas Medical Branch at Galveston have identified women who are likely to gain weight while using depot medroxyprogesterone acetate, more commonly known as Depo-Provera or the birth control shot. These findings dispel the myth that all women who use DMPA will gain weight and will help physicians to counsel patients appropriately.

24 Jul 2009

Insurers ‘spinning’ some data to shape health reform

Insurers sometimes cherry-pick facts to make their case against certain aspects of reform efforts, including a public plan, The Washington Post reports.

22 Jul 2009