Endocrinology News and Research

Latest Endocrinology News and Research

New genetic score is similar or more predictive than common risk factors for stroke

A group of investigators from Australia, Germany, and the UK have shown that genetic data obtained from a single blood draw or saliva sample can be used to identify individuals at a 3-fold increased risk of developing ischemic stroke, a devastating condition and one of the leading causes of disability and death world-wide.

20 Dec 2019

Links between most human diseases and genetics are shaky at best

In most cases, your genes have less than five per cent to do with your risk of developing a particular disease, according to new research by University of Alberta scientists.

20 Dec 2019

Data results of NCI-MATCH trial in tumors with DNA mismatch repair deficiencies

Final results are published from an evaluation of 42 patients treated with the immune checkpoint inhibitor nivolumab in the large multi-arm precision medicine trial, NCI-Molecular Analysis for Therapy Choice (NCI-MATCH or EAY131).

20 Dec 2019

Study finds differences in dialysis mortality for racial/ethnic groups in U.S. territories and states

A recent analysis found differences in mortality rates for various racial/ethnic groups among patients undergoing dialysis in the U.S. territories vs. the 50 U.S. states. The findings, which appear in an upcoming issue of CJASN, point to the need for research into the causes of these disparities.

19 Dec 2019

Almost one in two Americans will be obese by 2030

A shocking new study led by Harvard T.H. Chan School of Public Health reveals that by 2030, just a decade away, almost half of all Americans will be suffering from obesity – making this the biggest epidemic ever in history. And that’s not all – half of these obese individuals will be severely obese, or, to put it in simple terms, they will be over their expected weight by more than 100 pounds.

19 Dec 2019

Treating lipedema with liposuction could benefit women with 'painful fat' disease

Suppose you're a teen or young woman who starts putting on fat, mainly in your legs. Doctors say you're obese – but no matter how much you diet and exercise, you can't lose the fat. After years of weight gain, pain, and swelling, you're finally diagnosed with lipedema – a common but "enigmatic" disease of the peripheral fat.

19 Dec 2019

Caffeine may offset some negative health effects of obesogenic diet

A new study in rats suggests that caffeine may offset some of the negative effects of an obesogenic diet by reducing the storage of lipids in fat cells and limiting weight gain and the production of triglycerides.

19 Dec 2019

Powdered watermelon supplements provide health benefits to obese mice

Eating watermelon in the form of powdered supplements helped adult obese mice avoid some detrimental health effects of an unhealthy diet, according to a new Oregon State University study.

19 Dec 2019

New mechanism that impairs Treg differentiation and stability in type 1 diabetes discovered

Regulatory T cells (Tregs) prevent excessive immune reactions in healthy people. In the development of autoimmune type 1 diabetes, this protection is not sufficiently effective.

19 Dec 2019

The number of people who need renal replacement therapy is increasing

The ERA-EDTA Registry collects data on renal replacement therapy from the national and regional renal registries in Europe and from countries bordering the Mediterranean. For the 2017 Annual Report, data sets from 53 national or regional renal registries in 37 countries were compiled. A total population of 694,024,000 people was analyzed.

19 Dec 2019

Low diet quality, night eating during pregnancy linked to postpartum weight gain and retention

A study led by researchers from KK Women's and Children's Hospital (KKH) has found evidence that pregnant women who consume more of their daily food intake after 7.00 pm, and who consume lower quality diets during pregnancy, are more than three times more likely to experience postpartum weight retention of five kilograms or more, 18 months after giving birth.

19 Dec 2019

Researchers discover a way to move precision immunotherapy forward for multiple myeloma

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way to move precision immunotherapy forward by using genomics to inform immunotherapy for multiple myeloma, a blood cancer, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research, in December.

19 Dec 2019

UVA, Novo Nordisk partner to develop virtual patient modeling for type 2 diabetes

University of Virginia Center for Diabetes Technology and Novo Nordisk today announced that they have entered into a five-year research collaboration where UVA and Novo Nordisk will work together on the development of virtual environments focused on modelling of patients with type 2 diabetes.

19 Dec 2019

Gastric bypass associated with higher risk of additional operations

Research from the Harvard Pilgrim Health Care Institute finds that gastric bypass is associated with a higher risk of additional operations or other invasive procedures, compared to a gastric sleeve procedure.

19 Dec 2019

Declining dementia rates may be due to generational differences in lifetime lead exposure

To the medical community's surprise, several studies from the US, Canada, and Europe suggest a promising downward trend in the incidence and prevalence of dementia. Important risk factors for dementia, such as mid-life obesity and mid-life diabetes, have been increasing rapidly, so the decline in dementia incidence is particularly perplexing.

19 Dec 2019

New review provides guidance to address gaps in transgender health care

One of the biggest barriers to care for transgender individuals is a lack of knowledgeable providers.

19 Dec 2019

Study of Amazonian children provides clues for reversing global trends in obesity

Forager-horticulturalist children in the Amazon rainforest do not spend more calories in their everyday lives than children in the United States, but they do spend calories differently.

18 Dec 2019

Heavy drinking damages the heart

Drinking too much destroys the liver, as is well known. A new study published in the Journal of the American Heart Association on December 18, 2019, shows that excessive alcohol consumption also damages the heart muscle. This is seen by a rise in the level of certain biological molecules in the blood.

18 Dec 2019

Different mutations in a single gene can have myriad effects on a person's health

Mount Sinai researchers have found that different mutations in a single gene can have myriad effects on a person's health, suggesting that gene therapies may need to do more than just replenish the missing or dysfunctional protein the gene is supposed to encode, according to a study published in Nature Genetics in November.

18 Dec 2019

Worse long-term control of blood sugar increases risks in diabetic trauma patients

In trauma patients with diabetes, poorer long-term control of blood glucose levels is linked to a higher risk of death and trauma-related complications, reports a study in SHOCK: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, Official Journal of the Shock Society.

18 Dec 2019

Endocrinology News and Research

Latest Endocrinology News and Research

New genetic score is similar or more predictive than common risk factors for stroke

Links between most human diseases and genetics are shaky at best

Data results of NCI-MATCH trial in tumors with DNA mismatch repair deficiencies

Study finds differences in dialysis mortality for racial/ethnic groups in U.S. territories and states

Almost one in two Americans will be obese by 2030

Treating lipedema with liposuction could benefit women with 'painful fat' disease

Caffeine may offset some negative health effects of obesogenic diet

Powdered watermelon supplements provide health benefits to obese mice

New mechanism that impairs Treg differentiation and stability in type 1 diabetes discovered

The number of people who need renal replacement therapy is increasing

Low diet quality, night eating during pregnancy linked to postpartum weight gain and retention

Researchers discover a way to move precision immunotherapy forward for multiple myeloma

UVA, Novo Nordisk partner to develop virtual patient modeling for type 2 diabetes

Gastric bypass associated with higher risk of additional operations

Declining dementia rates may be due to generational differences in lifetime lead exposure

New review provides guidance to address gaps in transgender health care

Study of Amazonian children provides clues for reversing global trends in obesity

Heavy drinking damages the heart

Different mutations in a single gene can have myriad effects on a person's health

Worse long-term control of blood sugar increases risks in diabetic trauma patients

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Endocrinology News and Research

Latest Endocrinology News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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