Fatty Liver News and Research

Latest Fatty Liver News and Research

Omega-3 fatty acids especially DHA may have even wider range of biological impacts, shows study

A study of the metabolic effects of omega-3 fatty acids, especially DHA, concludes that these compounds may have an even wider range of biological impacts than previously considered, and suggests they could be of significant value in the prevention of fatty liver disease.

24 Jan 2014

Lack of SIRT1 protein in the liver leads to lower levels of liver FGF21

A new study led by Boston University School of Medicine demonstrates that the abnormal metabolism linked to obesity could be regulated in part by the interaction of two metabolic regulators, called the NAD-dependent deacetylase SIRT1 and fibroblast growth factor 21 (FGF21). Using experimental models, the researchers found that a lack of SIRT1 protein in the liver led to lower levels of a liver secreted protein FGF21, which resulted in an increased likelihood of developing fatty liver disease and obesity.

22 Jan 2014

AP-1 proteins modulate fat accumulation in liver, say researchers

Excessive alcohol consumption, as well as obesity leads to the accumulation of fat in the liver, a disease termed fatty liver disease (FLD) or steatosis. FLD is one of the most prevalent diseases in Western societies and affects about 30% of the adult population. Importantly, FLD increases the risk of liver failure, diabetes and cancer and no pharmacological therapies exist for this detrimental disease.

8 Jan 2014

Researchers reveal how metabolic system breaks down in obesity

Researchers at University of Michigan have illuminated an aspect of how the metabolic system breaks down in obesity. The findings provide additional evidence that a drug entering clinical trials at the university could reverse obesity, Type 2 diabetes and fatty liver disease in humans.

20 Dec 2013

FDA Advisory Committee recommends metreleptin for treatment of generalized lipodystrophy

AstraZeneca and Bristol-Myers Squibb Company (NYSE:BMY) today announced the U.S. Food and Drug Administration's (FDA) Endocrinologic and Metabolic Drugs Advisory Committee (EMDAC) recommends the investigational medicine metreleptin for the treatment of pediatric and adult patients with generalized lipodystrophy (LD).

12 Dec 2013

Pro-inflammatory proteins linked to obesity, metabolic syndrome in adults appear to protect young children

The first study of its kind, led by Melinda Sothern, PhD, CEP, Professor and Director of Behavioral and Community Health Sciences at LSU Health Sciences Center New Orleans School of Public Health, reveals that the same pro-inflammatory proteins linked to obesity and the metabolic syndrome in adults appear to protect children prior to puberty.

4 Dec 2013

Researchers discover how type 2 diabetes drug metformin actually works

Researchers from St. Vincent's Institute of Medical Research in Melbourne, Australia, in collaboration with researchers at McMaster University in Canada, are reportedly the first to discover how the type 2 diabetes drug metformin actually works, providing a molecular understanding that could lead to the development of more effective therapies. Mass spectrometry technologies from AB SCIEX, a global leader in analytical technologies, played a critical role in the analysis that led to this breakthrough finding.

25 Nov 2013

Obese children could suffer step back in life expectancy by up to 10 years

In Mexico, overweight or obese children could suffer a step back in life expectancy by up to 10 years. According to the National Institute of Geography and Statistics (INEGI), the life expectancy in Mexico is of 73 years for women and 76 years for men.

21 Nov 2013

Aerobic exercise may be superior to resistance exercise for obese teen girls

Obesity has more than doubled in children and tripled in adolescents in the United States in the past 30 years, according to the Centers for Disease Control and Prevention. The growing rate of childhood obesity is a major health concern since overweight and obese youth are at increased risk of developing several diseases once considered reserved for adults. These new pediatric diseases include type-2 diabetes, metabolic syndrome, and non-alcoholic fatty liver disease, a condition in which fat builds up in the liver, potentially impairing its function over time.

8 Nov 2013

Most severely obese teenagers who underwent bariatric WLS experience no major complications

Most severely obese teenagers who underwent bariatric weight-loss surgery (WLS) experienced no major complications, according to a study published by JAMA Pediatrics, a JAMA Network publication.

5 Nov 2013

McMaster University researchers discover how metformin drug works on fat in the liver

About 120 million people around the world with Type 2 diabetes - and two million in Canada - take the drug metformin to control their disease.

4 Nov 2013

Study: Sugar intake is not directly associated with nonalcoholic fatty liver disease

Despite current beliefs, sugar intake is not directly associated with nonalcoholic fatty liver disease, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. Rather, high-calorie diets promote the progression of this serious form of liver disease.

4 Nov 2013

Protective effect of estrogen in women with NASH against development of severe fibrosis

New research suggests that estrogen protects women with nonalcoholic steatohepatitis (NASH) from severe liver fibrosis. According to the study published online in Hepatology, a journal of the American Association for the Study of Liver Diseases, men are at higher risk of more severe fibrosis compared to women prior to menopause, but liver fibrosis severity is similar in men and post-menopausal women.

30 Oct 2013

Saint Luke's liver transplantation program receives CMS certification

The liver transplantation program at Saint Luke's Hospital of Kansas City has received certification by the Centers for Medicare and Medicaid. The certification is an important step in enhancing the hospital's ability to care for Medicare-covered patients suffering from end-stage liver disease, and attract other insurers who base their coverage on the CMS certification.

2 Oct 2013

Genetic study helps identify obese diabetes patients who are at risk of developing NAFLD

A groundbreaking study of nearly 2,300 extremely obese diabetes patients, led by the Translational Genomics Research Institute, has identified genes associated with unhealthy liver function.

2 Oct 2013

MRE imaging technique accurately detects chronic liver disease in children

A new, non-invasive imaging technique, magnetic resonance elastography (MRE), can now help physicians accurately detect fibrosis (scarring) in children with chronic liver disease - a growing problem due in part to increasing obesity rates.

21 Sep 2013

Causes of obesity, insulin resistance tied to fructose generated by the body

Researchers at the University of Colorado School of Medicine reported today that the cause of obesity and insulin resistance may be tied to the fructose your body makes in addition to the fructose you eat.

11 Sep 2013

Insomnia linked to GERD in nonalcoholic fatty liver disease

Insomnia appears to be relatively common in patients with nonalcoholic fatty liver disease and may occur, at least in part, as a result of gastroesophageal reflux disease symptoms, report researchers.

2 Sep 2013

Increased caffeine intake may reduce fatty liver in people with NAFLD

Surprise! Your morning cup of tea or coffee may be doing more than just perking you up before work. An international team of researchers led by Duke-NUS Graduate Medical School (Duke-NUS) and the Duke University School of Medicine suggest that increased caffeine intake may reduce fatty liver in people with non-alcoholic fatty liver disease (NAFLD).

17 Aug 2013

New test hints 3 sodas daily hurt lifespan, reproduction in mice

When mice ate a diet of 25 percent extra sugar - the mouse equivalent of a healthy human diet plus three cans of soda daily - females died at twice the normal rate and males were a quarter less likely to hold territory and reproduce, according to a toxicity test developed at the University of Utah.

14 Aug 2013

Fatty Liver News and Research

Latest Fatty Liver News and Research

Omega-3 fatty acids especially DHA may have even wider range of biological impacts, shows study

Lack of SIRT1 protein in the liver leads to lower levels of liver FGF21

AP-1 proteins modulate fat accumulation in liver, say researchers

Researchers reveal how metabolic system breaks down in obesity

FDA Advisory Committee recommends metreleptin for treatment of generalized lipodystrophy

Pro-inflammatory proteins linked to obesity, metabolic syndrome in adults appear to protect young children

Researchers discover how type 2 diabetes drug metformin actually works

Obese children could suffer step back in life expectancy by up to 10 years

Aerobic exercise may be superior to resistance exercise for obese teen girls

Most severely obese teenagers who underwent bariatric WLS experience no major complications

McMaster University researchers discover how metformin drug works on fat in the liver

Study: Sugar intake is not directly associated with nonalcoholic fatty liver disease

Protective effect of estrogen in women with NASH against development of severe fibrosis

Saint Luke's liver transplantation program receives CMS certification

Genetic study helps identify obese diabetes patients who are at risk of developing NAFLD

MRE imaging technique accurately detects chronic liver disease in children

Causes of obesity, insulin resistance tied to fructose generated by the body

Insomnia linked to GERD in nonalcoholic fatty liver disease

Increased caffeine intake may reduce fatty liver in people with NAFLD

New test hints 3 sodas daily hurt lifespan, reproduction in mice

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Fatty Liver News and Research

Latest Fatty Liver News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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