Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Experimental drug ozanimod moderately effective in treatment of ulcerative colitis

Researchers at University of California San Diego School of Medicine have shown that ozanimod (RPC1063), a novel drug molecule, is moderately effective in the treatment of ulcerative colitis. Results of the Phase II clinical trial will appear in the May 5 issue of the New England Journal of Medicine.

5 May 2016

Certain sugars in the body play key role in colitis, colon cancer development

An Oklahoma Medical Research Foundation scientist has discovered that certain sugars produced by the body play an important role in the development of colitis and, ultimately, colon cancer. The new finding could potentially lead to therapies for ulcerative colitis, Crohn's disease and colon cancer.

5 May 2016

Researchers develop computer model to reveal how antibiotic-resistant microbes develop and spread

Researchers from the Scientific Research Institute of Physical-Chemical Medicine, MIPT, the company M&S Decisions and the research department of Yandex have built a computer model of the interaction between different bacteria, and between bacteria and the gut wall.

5 May 2016

Human milk hormones may play vital role in shaping healthy infant microbiome

A new University of Colorado Anschutz Medical Campus study finds that hormones in breast milk may impact the development of healthy bacteria in infants' guts, potentially protecting them from intestinal inflammation, obesity and other diseases later in life.

5 May 2016

Candida yeast infections more common in men with schizophrenia or bipolar disorder

In a study prompted in part by suggestions from people with mental illness, Johns Hopkins researchers found that a history of Candida yeast infections was more common in a group of men with schizophrenia or bipolar disorder than in those without these disorders, and that women with schizophrenia or bipolar disorder who tested positive for Candida performed worse on a standard memory test than women with schizophrenia or bipolar disorder who had no evidence of past infection.

4 May 2016

Study shows syringe-like device acts as traffic cop directing bacteria to carry out infection

A study has found that a syringe-like device used to invade intestinal cells also acts as a traffic cop -- directing bacteria where to go and thereby enabling them to efficiently carry out infection.

4 May 2016

MII-pH can help doctors confirm diagnosis of GERD in newborns before treatment

Millions of Americans currently use medication for their indigestion and reflux, so it may come as no surprise that parents and doctors also prescribe medicine for newborns with reflux. However, according to a new study, newborns are likely being over treated the majority of the time with interventions - including surgery - that have risks for the infant.

3 May 2016

Half-strength apple juice followed by preferred fluid choice better for treating kids with mild gastroenteritis

Children with mild gastroenteritis and minimal dehydration experienced fewer treatment failures such as IV rehydration or hospitalization when offered half-strength apple juice followed by their preferred fluid choice compared with children who received electrolyte maintenance solution to replace fluid losses, according to a study published online by JAMA. The study is being released to coincide with its presentation at the Pediatric Academic Societies meeting.

2 May 2016

Early exposure to pathogens may play pivotal role in immune system development

Exposure to pathogens early in life is beneficial to the education and development of the human immune system.

30 Apr 2016

Novel gene therapy can treat pulmonary hypertension linked with heart failure

Scientists have used a novel gene therapy to halt the progression of pulmonary hypertension, a form of high blood pressure in the lung blood vessels that is linked to heart failure, according to a study led by Roger J. Hajjar, MD, Professor of Medicine and Director of the Cardiovascular Research Center at the Icahn School of Medicine at Mount Sinai.

30 Apr 2016

CMGH study offers insight into future interventions for Crohn's disease, chronic pancreatitis

Cellular and Molecular Gastroenterology and Hepatology is committed to publishing impactful digestive biology research covering a broad spectrum of themes in GI, hepatology and pancreatology. We wanted to share two new CMGH articles, which both offer important insight into future interventions for chronic conditions.

30 Apr 2016

Additional water or milk intake changes dietary pattern in overweight children

New research by Andersen et al, published in the International Journal of Food Sciences and Nutrition, may have an impact on the sugar tax debate. The research team observed overall changes in dietary patterns in overweight children, including a decrease in consumption of sugary drinks, when additional water or milk is added to their diet.

30 Apr 2016

Gut bacteria linked to risk of bloodstream infections after chemotherapy

A new study led by researchers at the University of Minnesota and Nantes University Hospital in France shows that the bacteria in people's gut may predict their risk of life-threatening blood infections following high-dose chemotherapy.

29 Apr 2016

New model can increase active surveillance for low-risk prostate cancer patients

Urologists at University of California, San Diego School of Medicine and Genesis Healthcare Partners have tested a new model of care for patients with low-risk prostate cancer. The evidence-based approach uses best practices to appropriately select and follow patients to avoid disease overtreatment. Results of the three-year study are now published online in the journal of Urology.

28 Apr 2016

Probiotic supplements may help treat post-menopausal osteoporosis

Probiotic supplements protected female mice from the loss of bone density that occurs after having their ovaries removed, researchers at Emory University School of Medicine and Georgia State University have shown.

28 Apr 2016

Research highlights global economic burden of norovirus

While norovirus is often linked in the news to outbreaks on cruise ships, the highly contagious stomach bug sickens nearly 700 million around the world every year and results in roughly $4.2 billion in health care costs and $60.3 billion in societal costs annually, new Johns Hopkins Bloomberg School of Public Health research suggests.

27 Apr 2016

Acid suppression drugs frequently prescribed for high-risk newborns, study shows

Since 2006, several published studies have associated the use of some acid suppression medications in hospitalized high-risk babies with infections, necrotizing enterocolitis and increased risk of death. Those medications - histamine-2 receptor antagonists, such as ranitidine (Zantac and others), and proton pump inhibitors, such as esomeprazole (Nexium and others) - were originally approved by the U.S. Food and Drug Administration for use in adults and older children.

27 Apr 2016

Researchers find strong possibility of preventing, curing neurological conditions using gut bacteria

Could bacteria in your gut be used to cure or prevent neurological conditions such as post-traumatic stress disorder (PTSD), anxiety or even depression? Two researchers sponsored by the Office of Naval Research (ONR) think that's a strong possibility.

26 Apr 2016

Study shows canine AD shares significant features of human version

Atopic dermatitis (AD), a chronic inflammatory skin condition and the most common form of eczema, is estimated to afflict as much as 10 percent of the U.S. population, and is much more common now than it was 50 years ago. Veterinary clinical estimates also show that approximately 10 percent of dogs have atopic dermatitis.

26 Apr 2016

Newly identified molecular pathway could lead to new treatments for reflux, incontinence disorders

Researchers at UMass Medical School have identified a new molecular pathway critical for maintaining the smooth muscle tone that allows the passage of materials through the digestive system.

25 Apr 2016

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Experimental drug ozanimod moderately effective in treatment of ulcerative colitis

Certain sugars in the body play key role in colitis, colon cancer development

Researchers develop computer model to reveal how antibiotic-resistant microbes develop and spread

Human milk hormones may play vital role in shaping healthy infant microbiome

Candida yeast infections more common in men with schizophrenia or bipolar disorder

Study shows syringe-like device acts as traffic cop directing bacteria to carry out infection

MII-pH can help doctors confirm diagnosis of GERD in newborns before treatment

Half-strength apple juice followed by preferred fluid choice better for treating kids with mild gastroenteritis

Early exposure to pathogens may play pivotal role in immune system development

Novel gene therapy can treat pulmonary hypertension linked with heart failure

CMGH study offers insight into future interventions for Crohn's disease, chronic pancreatitis

Additional water or milk intake changes dietary pattern in overweight children

Gut bacteria linked to risk of bloodstream infections after chemotherapy

New model can increase active surveillance for low-risk prostate cancer patients

Probiotic supplements may help treat post-menopausal osteoporosis

Research highlights global economic burden of norovirus

Acid suppression drugs frequently prescribed for high-risk newborns, study shows

Researchers find strong possibility of preventing, curing neurological conditions using gut bacteria

Study shows canine AD shares significant features of human version

Newly identified molecular pathway could lead to new treatments for reflux, incontinence disorders

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Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

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Automating research - solutions and best practices

How can microdialysis benefit drug development

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