Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Actavis seeks FDA ANDA approval for generic Zubsolv, confirms patent challenge

Actavis plc today confirmed that it has filed an Abbreviated New Drug Application (ANDA) with the U.S. Food and Drug Administration (FDA) seeking approval to market Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate Sublingual Tablets, Eq, 1.4 mg/0.36 mg and 5.7 mg/1.4 mg Base. Actavis' ANDA product is a generic version of Orexo's Zubsolv, which is a partial opioid agonist indicated for the maintenance treatment of opioid dependence.

30 Jun 2014

Synthetic Biologics supports SYN-004 C.difficile preventative program with formation of Clinical Advisory Board

Synthetic Biologics, Inc., a developer of novel anti-infective biologic and drug candidates targeting specific pathogens that cause serious infections and diseases, announced today the formation of a Clinical Advisory Board (CAB) to support development of SYN-004, the Company's lead anti-infective product candidate for the prevention of the devastating effects of Clostridium difficile (C. difficile)

30 Jun 2014

Phase III TAS-102 study for metastatic colorectal cancer shows improved survival

The new combination agent TAS-102 is able to improve overall survival compared to placebo in patients whose metastatic colorectal cancer is refractory to standard therapies, researchers said at the ESMO 16th World Congress on Gastrointestinal Cancer in Barcelona.

30 Jun 2014

patients with KRAS wild-type MCRC can benefit from Cetuximab Or Bevacizumab With Combi Chemo Equivalent For patients with KRAS wild-type MCRC

For patients with KRAS wild-type untreated colorectal cancer, adding cetuximab or bevacizumab to combination chemotherapy offers equivalent survival, researchers said at the ESMO 16th World Congress on Gastrointestinal Cancer in Barcelona.

30 Jun 2014

Taiho Oncology presents TAS-102 Phase III RECOURSE trial results in mCRC patients

Taiho Oncology, Inc., a subsidiary of Taiho Pharmaceutical Co., Ltd. (Japan), announced today detailed findings from its global Phase III RECOURSE trial of TAS-102 (nonproprietary names: trifluridine and tipiracil hydrochloride), an oral combination anticancer drug.

28 Jun 2014

New estimates highlight the importance of developing norovirus vaccines

Noroviruses are a leading cause of acute gastroenteritis (diarrhoea and vomiting) across all age groups, responsible for almost a fifth (18%) of all cases worldwide. New estimates, published in The Lancet Infectious Diseases, highlight the importance of developing norovirus vaccines, say the authors.

28 Jun 2014

Noroviruses responsible for almost a fifth of all cases of acute gastroenteritis

27 Jun 2014

Adding MM-398 to standard treatment improves survival in metastatic pancreatic cancer patients

Adding the novel MM-398 to standard treatment for metastatic pancreatic cancer patients who have already received gemcitabine improves survival, researchers said at the ESMO 16th World Congress on Gastrointestinal Cancer in Barcelona.

26 Jun 2014

Preventing antibiotic side effects: an interview with Florence Séjourné, CEO, Da Volterra

Like all drugs, antibiotics can have side-effects when administered to people. The most common (and often benign) side effect people experience when taking antibiotics is “associated diarrhea”. This illustrates the fact that antibiotics have an impact on the intestine!

25 Jun 2014

Ferring Pharmaceuticals, Roche partner to make personalised infertility treatment possible

Ferring Pharmaceuticals and Roche have announced a collaboration to combine diagnostic testing technology from Roche with Ferring's human cell line derived recombinant follicle-stimulating hormone (human rFSH), a gonadotrophin currently in phase III development.

24 Jun 2014

Researchers develop GI microbiome modulators to treat prediabetes and diabetes

In adults with prediabetes, a new drug that alters microbial populations and their environment in the gastrointestinal (GI) tract improves glucose tolerance-the body's response to consuming carbohydrates- after four weeks of treatment and without a change in diet.

24 Jun 2014

Antiviral therapy can reduce risk of liver cancer in patients with chronic hepatitis B infection

One of the most severe complications of hepatitis B is the development of liver cancer, which is responsible for approximately 745,000 deaths worldwide each year.

24 Jun 2014

Complementary medicines: an interview with Associate Professor Evelin Tiralongo, Griffith University

Complementary medicines are generally being defined as medicines which are non-mainstream medicines and are mostly given together with conventional medicines.

23 Jun 2014

UEG calls for more nurse endoscopy workforce to reduce CRC deaths

Colorectal cancer (CRC) is currently estimated to claim the lives of 214,675[1] adults in Europe, equivalent to 1 death every 3 minutes.

20 Jun 2014

New clinical guidelines on diagnosis and management of idiosyncratic DILI

New clinical guidelines on the diagnosis and management of idiosyncratic drug-induced liver injury (DILI) appear in the July issue of The American Journal of Gastroenterology.

18 Jun 2014

Symbion and Surgery Partners sign definitive merger agreement

Surgery Center Holdings Inc. ("Surgery Partners" or "The Company"), a portfolio company of H.I.G. Capital, LLC ("H.I.G."), and Symbion Holdings Corporation ("Symbion"), a portfolio company of Crestview Partners, have announced that they have entered into a definitive merger agreement under which Surgery Partners will acquire 100% of the stock of Symbion for a total purchase price of $792 million.

16 Jun 2014

Specific enzyme helps protect good commensal bacteria from harmful effects of antibiotics

Researchers from Case Western Reserve University in Cleveland have discovered that populating the gastrointestinal (GI) tracts of mice with Bacteroides species producing a specific enzyme helps protect the good commensal bacteria from the harmful effects of antibiotics.

13 Jun 2014

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Actavis seeks FDA ANDA approval for generic Zubsolv, confirms patent challenge

Synthetic Biologics supports SYN-004 C.difficile preventative program with formation of Clinical Advisory Board

Phase III TAS-102 study for metastatic colorectal cancer shows improved survival

patients with KRAS wild-type MCRC can benefit from Cetuximab Or Bevacizumab With Combi Chemo Equivalent For patients with KRAS wild-type MCRC

Taiho Oncology presents TAS-102 Phase III RECOURSE trial results in mCRC patients

New estimates highlight the importance of developing norovirus vaccines

Noroviruses responsible for almost a fifth of all cases of acute gastroenteritis

Adding MM-398 to standard treatment improves survival in metastatic pancreatic cancer patients

Preventing antibiotic side effects: an interview with Florence Séjourné, CEO, Da Volterra

Ferring Pharmaceuticals, Roche partner to make personalised infertility treatment possible

Researchers develop GI microbiome modulators to treat prediabetes and diabetes

Antiviral therapy can reduce risk of liver cancer in patients with chronic hepatitis B infection

Complementary medicines: an interview with Associate Professor Evelin Tiralongo, Griffith University

UEG calls for more nurse endoscopy workforce to reduce CRC deaths

New clinical guidelines on diagnosis and management of idiosyncratic DILI

Symbion and Surgery Partners sign definitive merger agreement

Specific enzyme helps protect good commensal bacteria from harmful effects of antibiotics

Dr Alenka Brooks scoops top prize for setting up Sheffield Women in Medicine network

Children's Hospital Los Angeles ranked among nation's top 5 again

New framework for monitoring oral cancer development, progression, recurrence

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Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

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How can microdialysis benefit drug development

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