Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Abbott seeks U.S. and E.U. approvals for Humira as a treatment for juvenile rheumatoid arthritis

Abbott has announced it has simultaneously submitted a supplemental Biologics License Application (sBLA) with the U.S. Food and Drug Administration (FDA) and a Type II Variation to the European Medicines Agency (EMEA) seeking approval to market HUMIRA (adalimumab) as a treatment for juvenile rheumatoid arthritis (JRA) in the U.S. and juvenile idiopathic arthritis (JIA) in the European Union (EU).

9 May 2007

Smoking and Crohn's disease

A new study in The American Journal of Gastroenterology suggests that smoking may determine which part of the intestinal tract is attacked in those who suffer from Crohn's disease.

4 May 2007

Child infections are an increasing concern in affluent countries

Dr Deborah Lehmann, who leads infectious diseases research at the Telethon Institute for Child Health Research, said the findings show that infection is an increasing concern in affluent countries.

4 May 2007

Racial disparities in treatment of patients with cirrhosis and complications of portal hypertension

African-American and Hispanic patients hospitalized for complications of portal hypertension were less likely to undergo a palliative shunt, prompt endoscopy, or liver transplantation compared to white patients, according to a new study in the May issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD).

2 May 2007

Infliximab fails to improve chronic obstructive pulmonary disease symptoms

A promising anti-inflammatory drug failed to improve symptoms of moderate to severe chronic obstructive pulmonary disease, or COPD, in a large, multi-center trial.

2 May 2007

Adalimumab shows potential for Crohn's disease

A study led by Mayo Clinic found that adalimumab (HUMIRA) is an effective treatment for adults with Crohn's disease who do not respond to infliximab (REMICADE) therapy.

2 May 2007

Wrapping version of Gleevec fights drug-resistant cancer

A new study highlighted on the cover of this week's issue of Cancer Research finds that the anti-cancer drug Gleevec? is far more effective against a drug-resistant strain of cancer when the drug wraps the target with a molecular bandage that seals out water from a critical area.

2 May 2007

Anti-reflux valve improves quality of life for cancer patients

An anti-reflux valve developed to help esophageal cancer patients also has been shown to help those with bile duct obstruction, according to Kulwinder S. Dua, M.D., a research physician at the Medical College of Wisconsin in Milwaukee.

30 Apr 2007

Researchers find clear genetic risk factors for type 2 diabetes

Scientists from the Broad Institute of Harvard and MIT, Lund University and Novartis have announced the discovery of three unsuspected regions of human DNA that contain clear genetic risk factors for type 2 diabetes, and another that is associated with elevated blood triglycerides.

27 Apr 2007

University of Nottingham tackles Helicobacter pylori

The occurrence of the disease is currently thought to be due to several factors including the toxic nature of the infecting strain, the genetic susceptibility of the host, and environmental factors.

26 Apr 2007

New method allows for stem cell propagation and neurogenesis in cell culture

Researchers are now able to study stem cells from the brains of adult mice and their neurogenesis in long-term cell cultures.

26 Apr 2007

Anti-reflux biliary stent helps those with bile duct obstruction

26 Apr 2007

Stomach bacteria may protect against asthma

Researchers have found that a bacteria found in the stomach, that can cause cancer and peptic ulcers, may have a role in protecting children from asthma.

24 Apr 2007

New FDA audio broadcasts provide emerging drug safety information

The U.S. Food and Drug Administration (FDA) is alerting health care professionals and consumers to the availability of audio broadcasts that provide emerging drug safety information.

24 Apr 2007

Inflammatory bowel disease linked to nerve damage and other neurological problems

People with inflammatory bowel disease may also be at risk for developing nerve damage and other neurological problems, according to research that will be presented at the American Academy of Neurology's 59th Annual Meeting in Boston, April 28 , May 5, 2007.

24 Apr 2007

Study links Helicobacter pylori to asthma prevention

The stomach bacterium Helicobacter pylori, which causes stomach cancer and peptic ulcers, may not be all bad.

24 Apr 2007

Discovery of important clue to the susceptibility of individuals to Crohn's disease

Crohn's disease is a chronic relapsing inflammatory disorder of the intestinal tract that affects an estimated 0.15% of people in the developed world. Common symptoms include abdominal pain and diarrhea, but the disorder is often associated with debilitating clinical complications.

21 Apr 2007

Taming chronic cough

Chronic cough – often causing much discomfort, frustration, irritability and sleep disturbances in 10 percent to 20 percent of adults – is one of the leading reasons for consultation with a physician according to a report published this month in Annals of Allergy, Asthma & Immunology , the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI).

21 Apr 2007

Lexicon-Genentech reveals potential therapeutic targets

Lexicon Genetics Incorporated has announced that data was presented highlighting potential therapeutic targets related to its collaboration with Genentech, Inc. at the Society for Biomolecular Sciences 13th Annual Conference & Exhibition in Montreal, Canada.

19 Apr 2007

Rotavirus can spread beyond the intestine into blood

A new study in PLoS Medicine has shown that children who have rotavirus, a very common cause of diarrhea in children, and who have antigens (protein fragments from the surface of the virus) in their blood, also have infectious virus in their blood.

18 Apr 2007