Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Mount Sinai receives $500,000 SU2C grant to identify therapeutic combinations for KRAS-mutant lung cancers

Mount Sinai is leading a team of lung cancer researchers that has been awarded a three-year, $500,000 grant from Stand Up To Cancer to explore therapeutic approaches to lung tumors with mutations in the KRAS gene, an undertaking that could have a significant impact for a large population of cancer patients who currently lack effective treatment options.

9 Aug 2022

Research reveals a gut-brain pathway that contributes to the development of Alzheimer’s disease

Research led by Drs. Yuhai Zhao and Walter J Lukiw at the LSU Health New Orleans Neuroscience Center and the Departments of Cell Biology and Anatomy, Neurology and Ophthalmology, reports for the first time a pathway that begins in the gut and ends with a potent pro-inflammatory toxin in brain cells contributing to the development of Alzheimer's disease (AD).

9 Aug 2022

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

Scientists review current literature associated with the role of the gut-brain axis in AD pathogenesis.

9 Aug 2022

Species across the animal kingdom show signs of cognitive impairment with disease

Is brain fog a condition limited to humans? "Infectious disease and cognition in wild populations," a recently published paper in Trends in Ecology & Evolution, answers that question. In a review of the studies, it explores whether learning, memory, and problem-solving are impaired by infection, not just in humans, but in species across the animal kingdom.

9 Aug 2022

Gut microbiota-derived metabolites offer protection against SARS-CoV-2

A new study investigated how the gut microbiome confers immunity to mammalian hosts against SARS-CoV-2 intranasal infection by generating short-chain fatty acids.

5 Aug 2022

Discovery could prevent insulin resistance and have significant benefits for people with type 2 diabetes

In a potential game changer for patients with type 2 diabetes, a team of researchers at the Diabetes, Obesity, and Metabolism Institute (DOMI) at the Icahn School of Medicine at Mount Sinai has identified a therapeutic target for the preservation and regeneration of beta cells (β cells)-;cells in the pancreas that produce and distribute insulin.

4 Aug 2022

Using native microbes as chassis for transgene delivery in live bacterial therapeutics

Residing within the human gut are trillions of bacteria and other microorganisms that can impact a variety of chronic human ailments, including obesity, type 2 diabetes, atherosclerosis, cancer, non-alcoholic fatty liver disease and inflammatory bowel disease.

4 Aug 2022

New low-calorie sweetener could potentially have a prebiotic effect on the gut microbiome

From the wide variety of sodas, candies and baked goods that are sold worldwide, it's clear that people love their sweet treats.

4 Aug 2022

The aging human brain

Researchers describe alterations at the molecular and cellular levels that underly brain aging in otherwise healthy elderly adults.

3 Aug 2022

Fruit fly genome contains whole genomes of a kind of bacteria, study finds

A fruit fly genome is not a just made up of fruit fly DNA – at least for one fruit fly species. New research from the University of Maryland School of Medicine's (UMSOM) Institute for Genome Sciences (IGS) shows that one fruit fly species contains whole genomes of a kind of bacteria, making this finding the largest bacteria-to-animal transfer of genetic material ever discovered. The new research also sheds light on how this happens.

3 Aug 2022

New research unravels why breastmilk-fed preemies are healthier than formula-fed infants

Human breastmilk has long been considered "liquid gold" among clinicians treating premature infants in a newborn intensive care unit.

2 Aug 2022

New, non-invasive imaging method may help detect an early indicator of glaucoma

A new, non-invasive ocular imaging method may be able to detect an early indicator of glaucoma in time to prevent disease progression and vision loss, according to a new study from New York Eye and Ear Infirmary of Mount Sinai.

2 Aug 2022

Gut microbe response to digestion may help explain cardiovascular disease risk related with red meat intake

Chemicals produced in the digestive tract by gut microbes after eating red meat may help explain part of the higher risk of cardiovascular disease associated with red meat consumption, according to new research published today in the American Heart Association's peer-reviewed journal Arteriosclerosis, Thrombosis, and Vascular Biology.

1 Aug 2022

Study quantifies link between red meat intake, gut microbiome, and cardiovascular disease in older adults

Does eating more meat-;especially red meat and processed meat-;raise the risk of cardiovascular disease, and if so, why? Despite intense study, the impact of animal source foods on atherosclerotic cardiovascular disease (ASCVD) is vigorously debated, and the mechanisms underlying potential effects of animal proteins remain unclear.

1 Aug 2022

Nutritive intervention could be an effective treatment method in maintaining human health

In a new study, researchers assessed the impact of dietary regulation on human health and disease.

1 Aug 2022

Study reveals how barrier cells that line the intestines send messages to patrolling T cells

Cells in the gut send secret messages to the immune system. Thanks to new research from La Jolla Institute for Immunology (LJI) scientists, we can finally get a look at what they're saying.

29 Jul 2022

Researchers use a tumor organoid system to examine bacterial effects on immunotherapy

Wake Forest Institute for Regenerative Medicine researchers are using a tumor organoid system to examine the effects of metabolites secreted by bacteria on a specialized immunotherapy – immune checkpoint blockage, a promising cancer treatment development – to determine why some patients don't respond or develop a resistance to the treatment over time.

29 Jul 2022

Prenatal opioid exposure may cause long-term neurological or behavioral effects later in a child's life

While infants exposed to opioids during their mother's pregnancy have been linked to adverse health outcomes, a new study at the University of Missouri has found prenatal opioid exposure could trigger long-term neurological or behavioral effects later in a child's life.

29 Jul 2022

People eating more fiber-rich food have very healthy microbiomes, study shows

That huge array of dietary fiber supplements in the drugstore or grocery aisle can be overwhelming to a consumer. They make all sorts of health claims too, not being subject to FDA review and approval. So how do you know which supplement works and would be best for you?

29 Jul 2022

RINVOQ® (upadacitinib) Approved by European Commission as an Oral Treatment for Adults with Active Non-Radiographic Axial Spondyloarthritis

With this approval, RINVOQ® is the first and only Janus Kinase inhibitor approved to treat patients across the spectrum of axial spondyloarthritis (nr-axSpA and ankylosing spondylitis) in the EU.

From AbbVie 29 Jul 2022

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Mount Sinai receives $500,000 SU2C grant to identify therapeutic combinations for KRAS-mutant lung cancers

Research reveals a gut-brain pathway that contributes to the development of Alzheimer’s disease

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

Species across the animal kingdom show signs of cognitive impairment with disease

Gut microbiota-derived metabolites offer protection against SARS-CoV-2

Discovery could prevent insulin resistance and have significant benefits for people with type 2 diabetes

Using native microbes as chassis for transgene delivery in live bacterial therapeutics

New low-calorie sweetener could potentially have a prebiotic effect on the gut microbiome

The aging human brain

Fruit fly genome contains whole genomes of a kind of bacteria, study finds

New research unravels why breastmilk-fed preemies are healthier than formula-fed infants

New, non-invasive imaging method may help detect an early indicator of glaucoma

Gut microbe response to digestion may help explain cardiovascular disease risk related with red meat intake

Study quantifies link between red meat intake, gut microbiome, and cardiovascular disease in older adults

Nutritive intervention could be an effective treatment method in maintaining human health

Study reveals how barrier cells that line the intestines send messages to patrolling T cells

Researchers use a tumor organoid system to examine bacterial effects on immunotherapy

Prenatal opioid exposure may cause long-term neurological or behavioral effects later in a child's life

People eating more fiber-rich food have very healthy microbiomes, study shows

RINVOQ® (upadacitinib) Approved by European Commission as an Oral Treatment for Adults with Active Non-Radiographic Axial Spondyloarthritis

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Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

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Automating research - solutions and best practices

How can microdialysis benefit drug development

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