Gene News and Research

Latest Gene News and Research

Researchers investigate hereditary breast cancer to find new treatment approaches

Deborah Kelly and Zhi Sheng, assistant professors at the Virginia Tech Carilion Research Institute, recently received a grant from the Commonwealth Health Research Board to investigate hereditary breast cancer, an effort that may lead to new treatment approaches.

30 Jul 2014

New stem-cell discovery may lead to more streamlined process for tissue regeneration

A new stem-cell discovery might one day lead to a more streamlined process for obtaining stem cells, which in turn could be used in the development of replacement tissue for failing body parts, according to UC San Francisco scientists who reported the findings in the current edition of Cell.

29 Jul 2014

Researchers find molecule that irreversibly interferes with activity of mutated cancer gene

UT Southwestern Medical Center cancer researchers have found a molecule that selectively and irreversibly interferes with the activity of a mutated cancer gene common in 30 percent of tumors.

29 Jul 2014

Researchers confirm for the first time that achalasia is autoimmune in origin

Achalasia is a rare disease - it affects 1 in 100,000 people - characterized by a loss of nerve cells in the esophageal wall.

29 Jul 2014

Researchers one step closer to finding treatment for Alzheimer's, other forms of dementia

There is no cure for Alzheimer's disease and other forms of dementia, but the research community is one step closer to finding treatment.

29 Jul 2014

Cancer researchers find molecule that irreversibly interferes with KRAS gene

UT Southwestern Medical Center cancer researchers have found a molecule that selectively and irreversibly interferes with the activity of a mutated cancer gene common in 30 percent of tumors.

29 Jul 2014

Research points to new direction for potential therapies to treat mucoepidermoid carcinoma

Research conducted at the Florida campus of The Scripps Research Institute has discovered links between a set of genes known to promote tumor growth and mucoepidermoid carcinoma, an oral cancer that affects the salivary glands. The discovery could help physicians develop new treatments that target the cancer's underlying genetic causes.

29 Jul 2014

Urinary microbiome altered in urge incontinence

The frequency and nature of bacteria in the urinary tract differs significantly between healthy women and those with urge incontinence, a US study demonstrates.

28 Jul 2014

PLXNA4 gene may increase risk of developing Alzheimer's disease

Researchers from Boston University School of Medicine report variants in a new gene, PLXNA4, which may increase the risk of developing Alzheimer's disease (AD). The discovery of this novel genetic association may lead to new drug treatment options that target PLXNA4 specifically.

28 Jul 2014

FDA clears Lorus' LOR-253 IND application for treatment of hematologic malignancies

Lorus Therapeutics Inc. today announced that the Food and Drug Administration completed its review and cleared the company's Investigational New Drug (IND) application of LOR-253 for the treatment of hematologic malignancies including acute myeloid leukemia (AML), high-risk myelodysplastic syndromes (MDS), lymphomas and multiple myeloma.

28 Jul 2014

Antifungal drug resistance evoked through RNAi-dependent epimutations

Microorganisms like bacteria and fungi can evade treatment by acquiring mutations in the genes targeted by antibiotics or antifungal drugs.

27 Jul 2014

Scientists find high proportion of oral bacteria in gut microbiota of liver cirrhosis patients

Scientists from INRA in collaboration with a Chinese team found that the gut microbiota[1] of individuals with liver cirrhosis differ notably from healthy individuals', showing a high proportion of oral bacteria.

26 Jul 2014

Xbp1s protein plays key role in brain regions to regulate metabolism

A protein that controls when genes are switched on or off plays a key role in specific areas of the brain to regulate metabolism, UT Southwestern Medical Center researchers have found.

26 Jul 2014

Montefiore-Einstein investigators to present new findings from eight abstracts at IFHNOS 2014

Clinicians and researchers from Montefiore Medical Center and the Albert Einstein College of Medicine of Yeshiva University will present new findings from eight abstracts at the International Federation of Head and Neck Oncologic Societies World Congress being held July 26 - July 30 in New York.

26 Jul 2014

Scientists discover new pathway to manipulate, maintain human ESCs in a "na-ve"

For years, researchers and patients have hoped that embryonic stem cells (ESCs)-capable of forming nearly any cell type in the body-could provide insight into numerous diseases perhaps even be used to treat them. Yet progress has been hampered by the inability to transfer research and tools from mouse ESC studies to their human counterparts, in part because human ESCs are "primed" and slightly less plastic than the mouse cells.

26 Jul 2014

Genetics involved with menarche may hold keys to preventing diabetes or osteoporosis in later life

A novel study shows that the age girls reach puberty is influenced by 'imprinted genes'-a subset of genes whose activity differs depending on which parent contributes the gene.

26 Jul 2014

Molecular testing panel increases likelihood of performing correct surgery for thyroid cancer patients

The routine use of a molecular testing panel developed at UPMC greatly increases the likelihood of performing the correct initial surgery for patients with thyroid nodules and cancer, report researchers from the University of Pittsburgh Cancer Institute (UPCI), partner with UPMC CancerCenter.

26 Jul 2014

Epigenetic switch can cause cancer, shows study

Cancer has long been thought to be primarily a genetic disease, but in recent decades scientists have come to believe that epigenetic changes - which don't change the DNA sequence but how it is 'read' - also play a role in cancer.

26 Jul 2014

EMA recommends full marketing approval for IMBRUVICA in the European Union

Pharmacyclics, Inc. today announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency issued a positive opinion recommending the granting of full marketing approval for IMBRUVICA (ibrutinib) in the European Union.

25 Jul 2014

Study identifies molecular mechanisms could lead to new therapies to treat obesity, diabetes

A protein that controls when genes are switched on or off plays a key role in specific areas of the brain to regulate metabolism, UT Southwestern Medical Center researchers have found.

25 Jul 2014

Gene News and Research

Latest Gene News and Research

Researchers investigate hereditary breast cancer to find new treatment approaches

New stem-cell discovery may lead to more streamlined process for tissue regeneration

Researchers find molecule that irreversibly interferes with activity of mutated cancer gene

Researchers confirm for the first time that achalasia is autoimmune in origin

Researchers one step closer to finding treatment for Alzheimer's, other forms of dementia

Cancer researchers find molecule that irreversibly interferes with KRAS gene

Research points to new direction for potential therapies to treat mucoepidermoid carcinoma

Urinary microbiome altered in urge incontinence

PLXNA4 gene may increase risk of developing Alzheimer's disease

FDA clears Lorus' LOR-253 IND application for treatment of hematologic malignancies

Antifungal drug resistance evoked through RNAi-dependent epimutations

Scientists find high proportion of oral bacteria in gut microbiota of liver cirrhosis patients

Xbp1s protein plays key role in brain regions to regulate metabolism

Montefiore-Einstein investigators to present new findings from eight abstracts at IFHNOS 2014

Scientists discover new pathway to manipulate, maintain human ESCs in a "na-ve"

Genetics involved with menarche may hold keys to preventing diabetes or osteoporosis in later life

Molecular testing panel increases likelihood of performing correct surgery for thyroid cancer patients

Epigenetic switch can cause cancer, shows study

EMA recommends full marketing approval for IMBRUVICA in the European Union

Study identifies molecular mechanisms could lead to new therapies to treat obesity, diabetes

eBook: Using iPSCs models for human disease research and drug discovery eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research