Gene News and Research

Latest Gene News and Research

Blood gene expression profile identifies patients with elevated risk of cardiovascular death

A study of 338 patients with coronary artery disease has identified a gene expression profile associated with an elevated risk of cardiovascular death. Used with other indicators such as biochemical markers and family history, the profile - based on a simple blood test - may help identify patients who could benefit from personalized treatment and counseling designed to address risk factors.

30 May 2014

New insights into egg selection may have broad implications for women's health, fertility

A woman's supply of eggs is a precious commodity because only a few hundred mature eggs can be produced throughout her lifetime and each must be as free as possible from genetic damage.

30 May 2014

New research shows how misfolded proteins are precisely selected for degradation

It's almost axiomatic that misfolded proteins compromise how cells normally function and cause debilitating human disease, but how these proteins are detected and degraded within the body is not well understood.

30 May 2014

New powerful tool helps identify disease-causing mutations in families

Scientists at the University of Utah (U of U), the University of Texas MD Anderson Cancer Center in Houston and colleagues have developed a powerful tool called pVAAST that combines linkage analysis with case control association to help researchers and clinicians identify disease-causing mutations in families faster and more precisely than ever before.

30 May 2014

Study reveals how BTK mutation triggers drug resistance in CLL patients

A multi-institutional team of researchers has pinpointed exactly what goes wrong when chronic lymphocytic leukemia (CLL) patients develop resistance to ibrutinib, a highly effective, precisely targeted anti-cancer drug.

29 May 2014

Researchers create initial catalog of human proteome, identify 193 novel proteins

Striving for the protein equivalent of the Human Genome Project, an international team of researchers has created an initial catalog of the human "proteome," or all of the proteins in the human body.

29 May 2014

Initial biopsy with epigenetic test rules out prostate cancer up to 88%

A multicenter team of researchers report that a commercial test designed to rule out the presence of genetic biomarkers of prostate cancer may be accurate enough to exclude the need for repeat prostate biopsies in many — if not most — men.

29 May 2014

Researchers design commercial test to rule out presence of genetic biomarkers of prostate cancer

29 May 2014

Study defines specific genetic mechanism that explains some of schizophrenia's heritability

The overall number and nature of mutations—rather than the presence of any single mutation—influences an individual's risk of developing schizophrenia, as well as its severity, according to a discovery by Columbia University Medical Center researchers published in the latest issue of Neuron.

29 May 2014

BioTime receives ISO 13485:2003 certification for development of BioTime HyStem hydrogels

BioTime, Inc. today announced that it has received ISO 13485:2003 certification from BSI (British Standards Institution) for design, development, manufacture, and distribution of BioTime HyStem® hydrogels for cell delivery applications.

28 May 2014

Polyplus-transfection introduces FectoPRO transfection reagent

Polyplus-transfection SA, a privately-held company specializing in the development of innovative solutions for transfection, today announces the launch of FectoPRO, the latest optimised transfection reagent in their product portfolio. FectoPRO has been designed for high yields in medium and large-scale production of proteins and antibodies in mammalian cells.

28 May 2014

Scientists collect new data on how "tumor suppressor" gene works

Scientists armed with a supercomputer and a vast trove of newly collected data on the body's most potent "tumor suppressor" gene have created the best map yet of how the gene works, an accomplishment that could lead to new techniques for fighting cancers, which are adept at disabling the gene in order to thrive.

28 May 2014

Study provides insight into genetic causes of cleft lip and cleft palate

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, have identified how a specific stretch of DNA controls far-off genes to influence the formation of the face.

28 May 2014

Genetically modified swine skin grafts may provide new treatment for burn injuries

A specially-bred strain of miniature swine lacking the molecule responsible for the rapid rejection of pig-to-primate organ transplants may provide a new source of skin grafts to treat seriously burned patients.

28 May 2014

Genetic variant linked to sudden cardiac death leads to protein overproduction in heart cells

A genetic variant linked to sudden cardiac death leads to protein overproduction in heart cells, Johns Hopkins scientists report. Unlike many known disease-linked variants, this one lies not in a gene but in so-called noncoding DNA, a growing focus of disease research.

28 May 2014

Findings may help medical researchers identify effective drug targets for triple negative breast cancer

The suppression of two genes reduce breast cancer tumor formation and metastasis by interfering with blood vessel formation and recruitment, report scientists from Houston Methodist and five other institutions in the Proceedings of the National Academy of Sciences (now online).

28 May 2014

Study detects hormone receptor's key role in normal organ development and function

A discovery by UC Irvine endocrinologists about the importance of cell surface receptors for estrogen has the potential to change how researchers view the hormone's role in normal organ development and function.

28 May 2014

Study reveals loss of function of gene RARRES3 in breast cancer cells promotes metastasis to lung

A study published today in EMBO Molecular Medicine reveals that the loss of function of the gene RARRES3 in breast cancer cells promotes metastasis to the lung.

28 May 2014

Researchers develop new technology that uses HIV virus as tool to fight against hereditary diseases

For the first time researchers have succeeded in altering HIV virus particles so that they can simultaneously, as it were, 'cut and paste' in our genome via biological processes. Developed at the Department of Biomedicine at Aarhus University, the technology makes it possible to repair genomes in a new way.

28 May 2014

Twist Bioscience raises $26M in Series B financing, receives $5.1M DARPA contract

Twist Bioscience today announced that it raised $26 million in a Series B financing to commercialize the company's semiconductor-based synthetic gene manufacturing process.

27 May 2014

Gene News and Research

Latest Gene News and Research

Blood gene expression profile identifies patients with elevated risk of cardiovascular death

New insights into egg selection may have broad implications for women's health, fertility

New research shows how misfolded proteins are precisely selected for degradation

New powerful tool helps identify disease-causing mutations in families

Study reveals how BTK mutation triggers drug resistance in CLL patients

Researchers create initial catalog of human proteome, identify 193 novel proteins

Initial biopsy with epigenetic test rules out prostate cancer up to 88%

Researchers design commercial test to rule out presence of genetic biomarkers of prostate cancer

Study defines specific genetic mechanism that explains some of schizophrenia's heritability

BioTime receives ISO 13485:2003 certification for development of BioTime HyStem hydrogels

Polyplus-transfection introduces FectoPRO transfection reagent

Scientists collect new data on how "tumor suppressor" gene works

Study provides insight into genetic causes of cleft lip and cleft palate

Genetically modified swine skin grafts may provide new treatment for burn injuries

Genetic variant linked to sudden cardiac death leads to protein overproduction in heart cells

Findings may help medical researchers identify effective drug targets for triple negative breast cancer

Study detects hormone receptor's key role in normal organ development and function

Study reveals loss of function of gene RARRES3 in breast cancer cells promotes metastasis to lung

Researchers develop new technology that uses HIV virus as tool to fight against hereditary diseases

Twist Bioscience raises $26M in Series B financing, receives $5.1M DARPA contract

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