Gene News and Research

Latest Gene News and Research

Early gene therapy could improve choroideremia prognosis

Retinal gene therapy could prevent loss of vision in patients with choroideremia and other retinal diseases, show the results of a phase I/II study.

30 Apr 2014

Researchers create tiny, biodegradable nanoparticles that carry DNA to brain cancer cells

Working together, Johns Hopkins biomedical engineers and neurosurgeons report that they have created tiny, biodegradable “nanoparticles” able to carry DNA to brain cancer cells in mice.

30 Apr 2014

Vertex: Conditions of PBAC recommendation may limit Australians who could benefit from KALYDECO

The Pharmaceutical Benefits Advisory Committee has again recommended KALYDECO (ivacaftor) for listing on the Pharmaceutical Benefits Scheme (PBS). However, Vertex is deeply disappointed in the conditions the PBAC has attached to the recommendation. These conditions fail to reflect the substantial clinical benefits recognised by the PBAC, and would result in limiting the number of eligible Australians who would be able to receive KALYDECO.

30 Apr 2014

Mother's diet before conception can permanently affect how her child's genes function

A mother's diet before conception can permanently affect how her child's genes function, according to a study published in Nature Communications.

30 Apr 2014

3D shape of leukemia cell's genome holds key to solving puzzle of human diseases

To solve a puzzle, you need to recognize shapes, patterns and a particular kind of order. In much the same way, researchers at McGill University have discovered that the 3D shape of a leukemia cell's genome holds a key to solving the puzzle of human diseases. The researchers report their findings in the open access journal Genome Biology.

30 Apr 2014

Higher calcium intake appears to mitigate impact of some of the risk genes for type 2 diabetes

Study shows calcium intake mitigates genetic risk for increased body fat in African-American children, a population with historically low calcium intake and high risk for diabetes.

29 Apr 2014

Illumina launches VeriSeq PGS for preimplantation genetic screening of embryos

Illumina, Inc. today announced the launch of VeriSeq PGS, a next-generation sequencing solution developed for preimplantation genetic screening of embryos using Illumina's NextSeq 500 and MiSeq® sequencing systems.

From Illumina, Inc. 29 Apr 2014

Gene expression profiling tests play critical role in women’s chemotherapy decision

Gene expression profiling tests play a critical role when women with early-stage breast cancer decide whether to have chemotherapy, but many of them do not fully understand what some of the test results mean, new research suggests.

29 Apr 2014

Study: Genetics as well as environment in womb play important roles in development of baby

A recent study led by A*STAR's Singapore Institute for Clinical Sciences (SICS) found that genetics as well as the environment in the womb play important roles in the development of the baby.

29 Apr 2014

Mayo Clinic launches new gene panel cancer test to help tailor chemotherapy

Mayo Clinic announces the launch of CANCP, a new gene panel cancer test to help tailor chemotherapy to the individual patient based on the unique genomic signature of the patient's tumor.

29 Apr 2014

Study illustrates how patient's genes can affect drug reaction and dosage

A new study out of Western University (London, Canada) illustrates the need for a lot more education around pharmacogenetics (PGx) -the study of how a patient's genes can affect drug reaction and dosage.

29 Apr 2014

Scientists identify first gene linked to childhood-onset familial dilated cardiomyopathy

Scientists at Icahn School of Medicine at Mount Sinai, along with collaborators at institutions in India, Italy, and Japan, have identified the first gene linked to childhood-onset familial dilated cardiomyopathy (DCM), one of the most common heart muscle diseases in children.

29 Apr 2014

Study: Mutations could have major impact on treatment of human blood diseases

A study published today in Nature Genetics has revealed mutations that could have a major impact on the future diagnosis and treatment of many human diseases.

29 Apr 2014

BRCA gene loss may accelerate cancer-promoting chromosome rearrangements

Inherited mutations in the BRCA1 or BRCA2 tumor suppressor genes are by far the most frequent contributors to hereditary cancer risk in the human population, often causing breast or ovarian cancer in young women of child-bearing age.

29 Apr 2014

Immunoregulatory genes modulate otitis media risk

Variation in genes involved in immunity influences children’s susceptibility to developing otitis media, according to research by a US team.

28 Apr 2014

Scientists use analysis of epigenetic marks on DNA to measure baby's development in womb

An international study, involving scientists at the University of Southampton, has used an analysis of epigenetic marks on DNA to measure how much a baby's development in the womb is determined by the genes inherited from the parents, as compared with the mother's nutrition, mental health and lifestyle.

28 Apr 2014

Life stressors may activate neurological disorders

When mothers are exposed to trauma, illness, alcohol or other drug abuse, these stressors may activate a single molecular trigger in brain cells that can go awry and activate conditions such as schizophrenia, post-traumatic stress disorder and some forms of autism.

26 Apr 2014

Finnish researchers discover gene mutation in ameloblastoma

A Finnish team of researchers was the first in the world to discover a gene mutation in ameloblastoma, which is a tumour of the jaw.

26 Apr 2014

Virginia Tech scientist receives grant to develop technique to detect subcellular location of protein

Virginia Tech chemical engineer Chang Lu and his colleagues have used a National Science Foundation grant to develop a technique to detect subcellular location of a protein.

26 Apr 2014

Researchers use RNA sequencing to look at early- and late-stage development of the heart

Most people think the development of the heart only happens in the womb, however the days and weeks following birth are full of cellular changes that play a role in the structure and function of the heart. Using mouse models, researchers at Baylor College of Medicine have now been able to categorize the alternative splicing (the process in which genes code proteins, determining their role) that takes place during these changes and what mechanisms they affect.

26 Apr 2014

Gene News and Research

Latest Gene News and Research

Early gene therapy could improve choroideremia prognosis

Researchers create tiny, biodegradable nanoparticles that carry DNA to brain cancer cells

Vertex: Conditions of PBAC recommendation may limit Australians who could benefit from KALYDECO

Mother's diet before conception can permanently affect how her child's genes function

3D shape of leukemia cell's genome holds key to solving puzzle of human diseases

Higher calcium intake appears to mitigate impact of some of the risk genes for type 2 diabetes

Illumina launches VeriSeq PGS for preimplantation genetic screening of embryos

Gene expression profiling tests play critical role in women’s chemotherapy decision

Study: Genetics as well as environment in womb play important roles in development of baby

Mayo Clinic launches new gene panel cancer test to help tailor chemotherapy

Study illustrates how patient's genes can affect drug reaction and dosage

Scientists identify first gene linked to childhood-onset familial dilated cardiomyopathy

Study: Mutations could have major impact on treatment of human blood diseases

BRCA gene loss may accelerate cancer-promoting chromosome rearrangements

Immunoregulatory genes modulate otitis media risk

Scientists use analysis of epigenetic marks on DNA to measure baby's development in womb

Life stressors may activate neurological disorders

Finnish researchers discover gene mutation in ameloblastoma

Virginia Tech scientist receives grant to develop technique to detect subcellular location of protein

Researchers use RNA sequencing to look at early- and late-stage development of the heart

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