Gene News and Research

Latest Gene News and Research

University of Michigan scientists uncover how cells block mutation-causing activity of junk DNA

There's a civil war going on inside every one of the 37 trillion cells in your body. Now, University of Michigan scientists have uncovered how your cells keep this war from causing too much collateral damage.

26 Apr 2014

Johns Hopkins research may help manage the disruptive effects experienced by shift workers

Johns Hopkins researchers report that they have identified a protein essential to the formation of the tiny brain region in mice that coordinates sleep-wake cycles and other so-called circadian rhythms.

26 Apr 2014

MGH investigators develop next-generation genome editing system

A next-generation genome editing system developed by Massachusetts General Hospital investigators substantially decreases the risk of producing unwanted, off-target gene mutations. In a paper receiving online publication in Nature Biotechnology, the researchers report a new CRISPR-based RNA-guided nuclease technology that uses two guide RNAs, significantly reducing the chance of cutting through DNA strands at mismatched sites.

26 Apr 2014

New study sheds light on mysterious gene that influences cardiovascular health

A new study from researchers at the University of Ottawa Heart Institute (UOHI), published today in Cell Reports, sheds light on a mysterious gene that likely influences cardiovascular health.

26 Apr 2014

Study shows pro-inflammatory cytokine TNF-α can speed recovery in mouse with pulmonary fibrosis

Inflammation has long been considered an integral part of the biological process that leads to deadly scarring in idiopathic pulmonary fibrosis. New research at National Jewish Health, however, suggests that a little inflammation may also be crucial to the healing and repair processes in the lungs.

26 Apr 2014

Promising new approach targets cancer protein to slow tumor growth

Sometimes a full-on assault isn't the best approach when dealing with a powerful enemy. A more effective approach, in the long run, may be to target the support system replenishing the supplies that keep your foe strong and ready for battle.

26 Apr 2014

MIT researchers develop test that can rapidly assess DNA repair systems

Our DNA is under constant attack from many sources, including environmental pollutants, ultraviolet light, and radiation. Fortunately, cells have several major DNA repair systems that can fix this damage, which may lead to cancer and other diseases if not mended.

25 Apr 2014

Researchers develop gene therapy reversing memory loss in mice with early-stage Alzheimer's

Alzheimer's disease is the first cause of dementia and affects some 400,000 people in Spain alone. However, no effective cure has yet been found. One of the reasons for this is the lack of knowledge on the cellular mechanisms which cause alterations in nerve transmissions and the loss of memory in the initial stages of the disease.

25 Apr 2014

Researchers use gold nanoparticles to detect, measure cancer levels in living cell

Purdue University researchers have developed a way to detect and measure cancer levels in a living cell by using tiny gold particles with tails of synthetic DNA.

25 Apr 2014

Prenatal smoking, genetic risk factors increase aggressive behavior in children

Researchers have found evidence of an interaction between prenatal smoking and genetic risk factors that increase aggressive behavior in children, especially in girls.

25 Apr 2014

Aspirin can lower colon cancer risk among people with high levels of specific gene

The humble aspirin may have just added another beneficial effect beyond its ability to ameliorate headaches and reduce the risk of heart attacks: lowering colon cancer risk among people with high levels of a specific type of gene.

25 Apr 2014

Research findings can impact lives of people with autism today

A new study from investigators with the Autism Genome Project, the world's largest research project on identifying genes associated with risk for autism, has found that the comprehensive use of copy number variant (CNV) genetic testing offers an important tool in individualized diagnosis and treatment of autism.

25 Apr 2014

Studies report new genetic disorder associated with degeneration of central/peripheral nervous systems

A newly identified genetic disorder associated with degeneration of the central and peripheral nervous systems in humans, along with the genetic cause, is reported in the April 24, 2014 issue of Cell.

25 Apr 2014

Tolero Pharmaceuticals' Alvocidib gets Orphan Drug Designation for acute myeloid leukemia treatment

Tolero Pharmaceuticals, Inc., a clinical-stage company developing treatments for serious hematological diseases, today announced that the U.S. Food and Drug Administration has granted Orphan Drug designation for Alvocidib for the treatment of patients with acute myeloid leukemia (AML).

23 Apr 2014

Meta-analysis links signalling pathways to bipolar disorder

A meta-analysis of genome-wide association studies has identified six biological pathways that may be involved in the genetic predisposition to develop bipolar disorder.

23 Apr 2014

Courtagen collaborates with CCMC to identify alterations in genes associated with ASD

Courtagen Life Sciences, Inc., an innovative molecular information company, announced today a collaboration with Connecticut Children's Medical Center to utilize Courtagen's sophisticated Next Generation Sequencing assays to help identify and characterize alterations found in genes associated with ASD.

23 Apr 2014

Personalis receives CAP accreditation

Personalis, Inc., a leading provider of genome-based diagnostics, announced today that its onsite clinical laboratory has received accreditation from the College of American Pathologists (CAP), meeting the highest standard of excellence in clinical laboratory practices.

23 Apr 2014

Exposure to microgravity can simulate aging for immune cells

Telling someone to "act your age" is another way of asking him or her to behave better. Age, however, does not always bring improvements.

23 Apr 2014

Investigators use computer-assisted approach to identify and rank new clock genes

Over the last few decades researchers have characterized a set of clock genes that drive daily rhythms of physiology and behavior in all types of species, from flies to humans.

23 Apr 2014

Research shows epigenetic changes contributed to human survival over other extinct species

In parallel with modern man (Homo sapiens), there were other, extinct types of humans with whom we lived side by side, such as Neanderthals and the recently discovered Denisovans of Siberia. Yet only Homo sapiens survived. What was it in our genetic makeup that gave us the advantage?

23 Apr 2014

Gene News and Research

Latest Gene News and Research

University of Michigan scientists uncover how cells block mutation-causing activity of junk DNA

Johns Hopkins research may help manage the disruptive effects experienced by shift workers

MGH investigators develop next-generation genome editing system

New study sheds light on mysterious gene that influences cardiovascular health

Study shows pro-inflammatory cytokine TNF-α can speed recovery in mouse with pulmonary fibrosis

Promising new approach targets cancer protein to slow tumor growth

MIT researchers develop test that can rapidly assess DNA repair systems

Researchers develop gene therapy reversing memory loss in mice with early-stage Alzheimer's

Researchers use gold nanoparticles to detect, measure cancer levels in living cell

Prenatal smoking, genetic risk factors increase aggressive behavior in children

Aspirin can lower colon cancer risk among people with high levels of specific gene

Research findings can impact lives of people with autism today

Studies report new genetic disorder associated with degeneration of central/peripheral nervous systems

Tolero Pharmaceuticals' Alvocidib gets Orphan Drug Designation for acute myeloid leukemia treatment

Meta-analysis links signalling pathways to bipolar disorder

Courtagen collaborates with CCMC to identify alterations in genes associated with ASD

Personalis receives CAP accreditation

Exposure to microgravity can simulate aging for immune cells

Investigators use computer-assisted approach to identify and rank new clock genes

Research shows epigenetic changes contributed to human survival over other extinct species

eBook: Using iPSCs models for human disease research and drug discovery eBook

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