Gene News and Research

Latest Gene News and Research

Researchers identify mutation in ITGA10 gene that causes chondrodysplasia in dog breeds

Professor Hannes Lohi's research group at the University of Helsinki and Folkhälsan Research Center has identified a mutation in ITGA10 gene, causing chondrodysplasia in two dog breeds, the Norwegian Elkhound and the Karelian Bear Dog.

26 Sep 2013

Three research groups awarded NIH grants to develop framework for evaluating genetic variants

Three grants totaling more than $25 million over four years will help three research groups to develop authoritative information on the millions of genomic variants relevant to human disease and the hundreds that are expected to be useful for clinical practice. The awards are from the National Institutes of Health.

26 Sep 2013

University of Michigan offers new test to improve PSA screening for prostate cancer

More than 1 million men will undergo a prostate biopsy this year, but only about one-fifth of those biopsies will result in a cancer diagnosis.

26 Sep 2013

Researchers identify existence of precursor cells in early prostate cancers

A team of cancer researchers at the University of California, San Diego has identified the existence of precursor cells in early prostate cancers. These cells are resistant to androgen-deprivation therapy, and may drive the subsequent emergence of recurrent or metastatic prostate cancer.

26 Sep 2013

MGH researchers identify rare gene mutations that appear to cause late-onset AD

Massachusetts General Hospital (MGH) researchers have identified and validated two rare gene mutations that appear to cause the common form of Alzheimer's disease (AD) that strikes after the age of 60.

25 Sep 2013

Researchers identify molecular pathway linking ICU ventilation to brain damage

At least 30 percent of patients in intensive care units (ICUs) suffer some form of mental dysfunction as reflected in anxiety, depression, and especially delirium. In mechanically-ventilated ICU patients, the incidence of delirium is particularly high, about 80 percent, and may be due in part to damage in the hippocampus, though how ventilation is increasing the risk of damage and mental impairment has remained elusive.

25 Sep 2013

Microbial clock: New tool to determine time of death

An intriguing study led by the University of Colorado Boulder may provide a powerful new tool in the quiver of forensic scientists attempting to determine the time of death in cases involving human corpses: a microbial clock.

25 Sep 2013

$Researchers show link between FTO gene and hip fracture in women$

Researchers show link between FTO gene and hip fracture in women

Australian researchers have demonstrated a strong association between the FTO (fat and obesity) gene and hip fracture in women. While the gene is already well known to affect diabetes and obesity, this is the first study to show that its high-risk variant can increase the risk of hip fracture by as much as 82%.

25 Sep 2013

Study shows how deadly Candida albicans might be rendered harmless

Candida albicans is a double agent: In most of us, it lives peacefully, but for people whose immune systems are compromised by HIV or other severe illnesses, it is frequently deadly. Now a new study from Johns Hopkins and Harvard Medical School shows how targeting a specific fungal component might turn the fungus from a lion back into a kitten.

25 Sep 2013

New And Improved Method For Analyzing Single-Cell Gene Expression

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24 Sep 2013

Rhythm starts RM-493 clinical trials in obesity patients with genetic deficiency

Rhythm announced today the initiation of the first of a series of clinical trials with RM-493, the company's novel melanocortin 4 receptor (MC4R) agonist, for the treatment of obesity in individuals with a genetic deficiency in the MC4R pathway.

24 Sep 2013

Understanding genetic, physiological basis for metabolic diseases related to circadian function

A new study by a team of University of Notre Dame researchers, which appears in the Sept. 2 edition of the journal PLoS ONE, is a significant step in understanding the molecular genetic and physiological basis for a spectrum of metabolic diseases related to circadian function.

24 Sep 2013

New research unveils role of ORMDL3 gene in asthma

New research from the University of Minnesota College of Veterinary Medicine has uncovered the role gene ORMDL3 plays in the disease asthma. ORMDL3, a gene recently linked to asthma susceptibility, has now been linked to the body's ability to recruit inflammatory cells during an airway allergic reaction. Study findings appear today in the journal Nature Communications.

24 Sep 2013

Researchers discover drug that halts growth of brain tumor cells

Working with mice, Johns Hopkins researchers have discovered that weeks of treatment with a repurposed FDA-approved drug halted the growth of - and ultimately left no detectable trace of - brain tumor cells taken from adult human patients.

24 Sep 2013

New regulatory mechanism could help develop novel therapies for cancer

Molecular microbiologists at the University of Southern California (USC) have uncovered intricate regulatory mechanisms within the cell that could lead to novel therapeutics for the treatment of cancer and other diseases.

23 Sep 2013

Boys’ chronic aggressive behavior may be due to epigenetic changes during pregnancy, early childhood

Chronic aggressive behaviour exhibited by some boys from disadvantaged families may be due to epigenetic changes during pregnancy and early childhood.

23 Sep 2013

Researchers develop new, improved technique for single-cell gene expression analysis

A team of researchers affiliated with Ludwig Cancer Research and the Karolinska Institutet in Sweden report in the current issue of Nature Methods a dramatically improved technique for analyzing the genes expressed within a single cell -- a capability of relevance to everything from basic research to future cancer diagn

23 Sep 2013

Veracyte files registration statement relating to proposed initial public offering of common stock

Veracyte, Inc. today announced that it has filed a registration statement on Form S-1 with the Securities and Exchange Commission relating to a proposed initial public offering of its common stock. All of the shares to be sold in the proposed offering will be offered by Veracyte, Inc.

21 Sep 2013

Research on synapse stabilization aids understanding of autism, schizophrenia, intellectual disability

When we're born, our brains aren't very organized. Every brain cell talks to lots of other nearby cells, sending and receiving signals across connections called synapses.

21 Sep 2013

Study shows how lifestyle factors can influence metabolism via resulting alterations in DNA

In the course of life, aging processes, environmental influences and lifestyle factors such as smoking or diet induce biochemical alterations to the DNA. Frequently, these lead to DNA methylation, a process in which methyl groups are added to particular DNA segments, without changing the DNA sequence.

21 Sep 2013

Gene News and Research

Latest Gene News and Research

Researchers identify mutation in ITGA10 gene that causes chondrodysplasia in dog breeds

Three research groups awarded NIH grants to develop framework for evaluating genetic variants

University of Michigan offers new test to improve PSA screening for prostate cancer

Researchers identify existence of precursor cells in early prostate cancers

MGH researchers identify rare gene mutations that appear to cause late-onset AD

Researchers identify molecular pathway linking ICU ventilation to brain damage

Microbial clock: New tool to determine time of death

Researchers show link between FTO gene and hip fracture in women

Study shows how deadly Candida albicans might be rendered harmless

New And Improved Method For Analyzing Single-Cell Gene Expression

Rhythm starts RM-493 clinical trials in obesity patients with genetic deficiency

Understanding genetic, physiological basis for metabolic diseases related to circadian function

New research unveils role of ORMDL3 gene in asthma

Researchers discover drug that halts growth of brain tumor cells

New regulatory mechanism could help develop novel therapies for cancer

Boys’ chronic aggressive behavior may be due to epigenetic changes during pregnancy, early childhood

Researchers develop new, improved technique for single-cell gene expression analysis

Veracyte files registration statement relating to proposed initial public offering of common stock

Research on synapse stabilization aids understanding of autism, schizophrenia, intellectual disability

Study shows how lifestyle factors can influence metabolism via resulting alterations in DNA

eBook: Using iPSCs models for human disease research and drug discovery eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research