Gene News and Research

Latest Gene News and Research

23andMe granted FDA approval to market direct-to-consumer genetic test under novel device classification

23andMe, Inc., the leading personal genetics company, today announced that it has been granted authority by the U.S. Food and Drug Administration (FDA) to market the first direct-to-consumer genetic test under a regulatory classification for novel devices.

20 Feb 2015

Study: Growth hormone can improve social impairment in patients with Phelan-McDermid syndrome

A growth hormone can significantly improve the social impairment associated with autism spectrum disorder (ASD) in patients with a related genetic syndrome, according to a pilot study conducted at the Icahn School of Medicine at Mount Sinai and published yesterday on Pub Med, a public database of biomedical topics maintained by the National Institutes of Health (study originally published in the December 12 issue of the journal Molecular Autism).

20 Feb 2015

Study helps solve mystery about how genetic variations can increase cancer risk

Single-letter genetic variations within parts of the genome once dismissed as 'junk DNA' can increase cancer risk through wormhole-like effects on far-off genes, new research shows.

19 Feb 2015

Research findings could someday lead to new treatments for patients with autism and cancer

In recent years, scientists have found a surprising a connection between some people with autism and certain cancer patients: They have mutations in the same gene, one that codes for a protein critical for normal cellular health. Now scientists have reported in the ACS journal Biochemistry that the defects reduce the activity and stability of the protein.

19 Feb 2015

UT Dallas study reports new gene therapy approach

Bioengineers at The University of Texas at Dallas have created a novel gene-delivery system that shuttles a gene into a cell, but only for a temporary stay, providing a potential new gene-therapy strategy for treating disease.

19 Feb 2015

Duke researchers demonstrate genetic therapeutic technique to treat DMD patients

Duke researchers have demonstrated a genetic therapeutic technique that has the potential to treat more than half of the patients suffering from Duchenne Muscular Dystrophy (DMD).

19 Feb 2015

Weill Cornell receives NIH grant to study TB-causing bacteria

In an effort to stop tuberculosis (TB) from becoming progressively less treatable worldwide, the National Institutes of Health has awarded Weill Cornell Medical College more than $6.2 million in first-year funding to support a research collaboration among six institutions in close alliance with voluntary pharmaceutical partners.

19 Feb 2015

New molecule shows promise in controlling HIV without using daily antiretroviral drugs

Scientists have created a new molecule that shows promise for controlling HIV without daily antiretroviral drugs. The molecule foils a wider range of HIV strains in the laboratory than any known broadly neutralizing HIV antibody and is more powerful than some of the most potent of these antibodies.

19 Feb 2015

Researchers assemble comprehensive map of human epigenome

Virtually every cell in the body carries an identical genome. But how is it possible that each of the body's 200 different types of specialized cells - in the heart, brain, bone, skin and elsewhere - develops from the same DNA instruction book?

19 Feb 2015

Scientists map autism genetic pathway that regulates brain development

Scientists at the University of California, San Diego School of Medicine have found that mutations that cause autism in children are connected to a pathway that regulates brain development. The research, led by Lilia Iakoucheva, PhD, assistant professor in the Department of Psychiatry, is published in the February 18 issue of Neuron.

19 Feb 2015

Epigenome may hold promise for conquering diseases

The human genome project captured the public imagination when its first draft was published 14 years ago this week in the international science journal Nature, but the epigenome may hold the real promise for conquering disease.

19 Feb 2015

New facts provide baseline for future studies of epigenome's role in human development, diseases

While genomics is the study of all of the genes in a cell or organism, epigenomics is the study of all the genomic add-ons and changes that influence gene expression but aren't encoded in the DNA sequence. A variety of new epigenomic information is now available in a collection of studies published Feb. 19 in Nature by the National Institutes of Health Roadmap Epigenomics Program.

19 Feb 2015

UCSD researchers make new attempt to develop malaria vaccine candidate

Researchers at University of California, San Diego School of Medicine used algae as a mini-factory to produce a malaria parasite protein. The algae-produced protein, paired with an immune-boosting cocktail suitable for use in humans, generated antibodies in mice that nearly eliminated mosquito infection by the malaria parasite.

19 Feb 2015

First comprehensive maps and analyses of human epigenomes revealed

Two dozen scientific papers published online simultaneously on Feb. 18, 2015 present the first comprehensive maps and analyses of the epigenomes of a wide array of human cell and tissue types. Epigenomes are patterns of chemical annotations to the genome that determine whether, how, and when genes are activated.

18 Feb 2015

Findings may help doctors recommend appropriate treatments, improve patient outcomes

Like a car's front and back bumpers, your cell's chromosomes are capped by "telomeres" that protect this genetic material against deterioration. Still, after enough replications, a chromosome's telomeres break down and once they reach a certain point of degradation, the cell dies. This is one reason that cells are mortal: telomeres only last so long. That is, unless the enzyme telomerase builds new material onto the worn telomeres to reinforce these chromosomal "bumpers". Telomere repair can be a good thing, but in some cases it's not: overactive telomerase can lengthen telomeres until a cell becomes immortal…leading to cancer.

18 Feb 2015

Facts about precision medicine

President Barack Obama is requesting an increase of $215 million in the 2016 federal budget to launch the Precision Medicine Initiative. This boost in funding for research will give genetic causes of cancer a national focus specifically around precision or "personalized" treatments for cancer in the future.

18 Feb 2015

Scientists identify role of tau-associated MAPT gene in development of Alzheimer's disease

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, has identified the microtubule-associated protein tau (MAPT) gene as increasing the risk for developing Alzheimer's disease (AD).

18 Feb 2015

Research may lead to future medical treatments for children with neurodevelopmental problems

Children born with a DNA abnormality on chromosome 16 already linked to neurodevelopmental problems show measurable delays in processing sound and language, says a study team of radiologists and psychologists.

18 Feb 2015

Fetal exposure to drugs can cause neurological problems

Research suggests that fetal exposure to chemicals or drugs can cause neurological problems. Babies whose mothers take the epilepsy drug valporic acid (VPA) during pregnancy, for example, appear to have an elevated risk of developing an autism spectrum disorder.

18 Feb 2015

Trinity scientists reveal new marvel molecule that can block key process in inflammatory diseases

Scientists at Trinity College Dublin have uncovered a marvel molecule that blocks a key driver of inflammatory diseases. The finding could meet a major unmet clinical need by inspiring new non-invasive treatments for arthritis, multiple sclerosis and Muckle-Wells syndrome, among a myriad of other inflammatory diseases.

18 Feb 2015

Gene News and Research

Latest Gene News and Research

23andMe granted FDA approval to market direct-to-consumer genetic test under novel device classification

Study: Growth hormone can improve social impairment in patients with Phelan-McDermid syndrome

Study helps solve mystery about how genetic variations can increase cancer risk

Research findings could someday lead to new treatments for patients with autism and cancer

UT Dallas study reports new gene therapy approach

Duke researchers demonstrate genetic therapeutic technique to treat DMD patients

Weill Cornell receives NIH grant to study TB-causing bacteria

New molecule shows promise in controlling HIV without using daily antiretroviral drugs

Researchers assemble comprehensive map of human epigenome

Scientists map autism genetic pathway that regulates brain development

Epigenome may hold promise for conquering diseases

New facts provide baseline for future studies of epigenome's role in human development, diseases

UCSD researchers make new attempt to develop malaria vaccine candidate

First comprehensive maps and analyses of human epigenomes revealed

Findings may help doctors recommend appropriate treatments, improve patient outcomes

Facts about precision medicine

Scientists identify role of tau-associated MAPT gene in development of Alzheimer's disease

Research may lead to future medical treatments for children with neurodevelopmental problems

Fetal exposure to drugs can cause neurological problems

Trinity scientists reveal new marvel molecule that can block key process in inflammatory diseases

Genomics - Industry Focus eBook (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research