Gene News and Research

Latest Gene News and Research

Scientists discover how BRCA1 gene mutations predispose women to breast and ovarian cancers

Scientists led by Drs. Mona Gauthier and Tak Mak at The Campbell Family Institute for Breast Cancer Research at the Princess Margaret Cancer Centre have solved a key piece in the puzzle of how BRCA1 gene mutations specifically predispose women to breast and ovarian cancers.

16 Jul 2013

Assurex Health announces release of new psychiatric pharmacogenomic test panel

Assurex Health today announced the release of GeneSight Psychotropic 2.0, its lead psychiatric pharmacogenomic test panel. This latest GeneSight Psychotropic version has been updated to include four additional medications that now cover a total of 36 of the most commonly prescribed psychotropic medications in the US.

15 Jul 2013

FDA approves QIAGEN’s therascreen EGFR test as companion diagnostic for NSCLC patients

QIAGEN N.V. (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) today announced it has received approval by the U.S. Food and Drug Administration (FDA) to market the therascreen EGFR test as a companion diagnostic to guide the use of Boehringer Ingelheim's new targeted therapy, GILOTRIF™ (afatinib), for treatment of metastatic NSCLC in patients whose tumors have certain EGFR gene mutations.

From QIAGEN Manchester Limited 15 Jul 2013

TSRI scientists design drug candidate that increases exercise endurance in animal models

An international group of scientists has shown that a drug candidate designed by scientists from the Florida campus of The Scripps Research Institute (TSRI) significantly increases exercise endurance in animal models.

15 Jul 2013

New discovery reveals how RNA moves genetic information from DNA to create proteins

The discovery cracks the "RNA control code," which dictates how RNA - a family of molecules that mediates DNA expression - moves genetic information from DNA to create proteins.

15 Jul 2013

New theory challenges orthodox view that cancer develops in each host by mutational accidents

A new way to look at cancer -- by tracing its deep evolutionary roots to the dawn of multicellularity more than a billion years ago -- has been proposed by Paul Davies of Arizona State University's Beyond Center for Fundamental Concepts in Science in collaboration with Charles Lineweaver of the Australian National University.

15 Jul 2013

'Defanged' HIV used to deliver gene therapy

Researchers are having success using a "defanged" version of HIV to deliver gene therapy to children suffering from genetic diseases, a development that could improve other such care.

15 Jul 2013

Researchers identify important component for regulating stem cell niches

Proper tissue function and regeneration is supported by stem cells, which reside in so-called niches. New work from Carnegie's Yixian Zheng and Haiyang Chen identifies an important component for regulating stem cell niches, with impacts on tissue building and function. The results could have implications for disease research. It is published by Cell Stem Cell.

15 Jul 2013

First Edition: July 12, 2013

Today's early morning highlights from the major news organizations, including articles on data tracking of doctors and comparing the rollout of the Medicare Part D drug plans to implementation of the federal health law.

12 Jul 2013

RXi Pharmaceuticals reports positive results from second Phase 1 study with RXI‑109

RXi Pharmaceuticals Corporation, a biotechnology company focused on discovering, developing and commercializing innovative therapies addressing major unmet medical needs using RNA-targeted technologies, today announced positive results from their second placebo-controlled Phase 1 study with RXI‑109, an sd-rxRNA compound that targets Connective Tissue Growth Factor, and is being developed for the treatment of abnormal dermal scars such as hypertrophic scars and keloids in conjunction with scar revision surgery.

12 Jul 2013

International team explores genetic diversity of Plasmodium vivax in the Americas

Human migrations - from the prehistoric epoch to the present day - have extended cultures across the globe. With these travelers have come unwanted stowaways: mosquito-borne parasites belonging to the Plasmodium species - a group responsible for malaria, worldwide.

12 Jul 2013

Scientists discover chain of molecular mechanisms set in motion by glucocorticoids

These scientists under the leadership of Martin Bilban from the Clinical Institute of Laboratory Medicine at the MedUni Vienna discovered a chain of molecular mechanisms, which is kick-started by the formation of glucocorticoids.

12 Jul 2013

Genome sequencing promises to identify rare mutations that give rise to autism

An international consortium, consisting of Autism Speaks, Duke University School of Medicine, The Hospital for Sick Children of Toronto, BGI and other institutes, has investigated the genetic variants in 32 families with Autism Spectrum Disorder (ASD).

12 Jul 2013

Seven scientists to receive Annual Klerman and Freedman Prizes from Brain & Behavior Research Foundation

Seven young scientists will be recognized by the Brain & Behavior Research Foundation at its presentation of the Annual Klerman and Freedman Prizes on Friday July 26, 2013 at Le Parker Meriden Hotel, New York, NY.

12 Jul 2013

Alnylam releases positive top-line data from ALN-TTRsc Phase I trial for TTR-mediated amyloidosis

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today positive top-line results from its ongoing Phase I trial of ALN-TTRsc, a subcutaneously administered RNAi therapeutic targeting the transthyretin gene for the treatment of TTR-mediated amyloidosis.

12 Jul 2013

Seven named recipients of GSA poster awards at 19th International C. elegans Meeting

Six graduate students and one undergraduate were named as recipients of Genetics Society of America poster awards at the 19th International C. elegans Meeting, held June 26 on the campus of the University of California, Los Angeles.

12 Jul 2013

Researchers identify receptor mutation that blocked estrogen action in young woman

A receptor mutation that essentially blocks estrogen's action has been identified for the first time a female, researchers report.

12 Jul 2013

Hydrogel method form synthetic scaffolds to support formation of blood vessels in engineered tissues

Next-generation hydrogels can form synthetic scaffolds to support the formation of replacement tissues and organs in the emerging area of regenerative medicine. Embedding peptides into the hydrogels stimulates the growth of essential microvascular networks to ensure a good blood supply.

12 Jul 2013

Phase III study: REVLIMID meets primary endpoint in patients newly diagnosed with multiple myeloma

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation, today announced that its phase III study (MM-020/IFM 07-01) of REVLIMID (lenalidomide) in combination with dexamethasone in patients newly diagnosed with multiple myeloma met its primary endpoint of progression-free survival.

11 Jul 2013

ELSIP: Integrating personalized medicine into clinical practice

Lynn G. Dressler Dr. P.H. Director, Personalized Medicine and Pharmacogenomics, Mission Health, Fullerton Genetics Center will present: Addressing the Ethical, Legal, Social and Policy Issues Related to Integrating Personalized Medicine into Routine Clinical Care at the 5th Annual Personalized Medicine Conference in Boston, MA on October 21- 22, 2013.

11 Jul 2013

Gene News and Research

Latest Gene News and Research

Scientists discover how BRCA1 gene mutations predispose women to breast and ovarian cancers

Assurex Health announces release of new psychiatric pharmacogenomic test panel

FDA approves QIAGEN’s therascreen EGFR test as companion diagnostic for NSCLC patients

TSRI scientists design drug candidate that increases exercise endurance in animal models

New discovery reveals how RNA moves genetic information from DNA to create proteins

New theory challenges orthodox view that cancer develops in each host by mutational accidents

'Defanged' HIV used to deliver gene therapy

Researchers identify important component for regulating stem cell niches

First Edition: July 12, 2013

RXi Pharmaceuticals reports positive results from second Phase 1 study with RXI‑109

International team explores genetic diversity of Plasmodium vivax in the Americas

Scientists discover chain of molecular mechanisms set in motion by glucocorticoids

Genome sequencing promises to identify rare mutations that give rise to autism

Seven scientists to receive Annual Klerman and Freedman Prizes from Brain & Behavior Research Foundation

Alnylam releases positive top-line data from ALN-TTRsc Phase I trial for TTR-mediated amyloidosis

Seven named recipients of GSA poster awards at 19th International C. elegans Meeting

Researchers identify receptor mutation that blocked estrogen action in young woman

Hydrogel method form synthetic scaffolds to support formation of blood vessels in engineered tissues

Phase III study: REVLIMID meets primary endpoint in patients newly diagnosed with multiple myeloma

ELSIP: Integrating personalized medicine into clinical practice

eBook: Using iPSCs models for human disease research and drug discovery eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research