Gene News and Research

Latest Gene News and Research

Study shows molecular mechanism behind type 3c pancreatic diabetes

Mice develop pancreatic diabetes (type 3c) when they lack certain genes in the E2F group, and to understand how this happens, Olatz Zenarruzabeitia has focussed on the molecular mechanism behind it.

29 Aug 2012

Genetic investigation of tribes may explain why East Asians have lower skin cancer rates

Genetic investigation of a Malaysian tribe may tell scientists why East Asians have light skin but lower skin cancer rates than Europeans, according to a team of international researchers. Understanding the differences could lead to a better way to protect people from skin cancer.

29 Aug 2012

FISH assay identifies only few lung cancer patients who could benefit from crizotinib

Break apart a couple worm-like chromosomes and they may reconnect with mismatched tips and tails - such is the case of the EML4-ALK fusion gene that creates 2-7 percent of lung cancers. Almost exactly a year ago, the FDA approved the drug crizotinib to treat these ALK+ lung cancer patients, who were likely never smokers. Informed doctors use the test called a FISH assay to check for the EML4-ALK fusion gene, and then if the test is positive, ALK+ patients benefit greatly from crizotinib.

29 Aug 2012

Scientists decode signals that boost the burning of fat

The numbers of obese people are climbing steeply all over the world - with obvious major consequences for their health. Due to excess food intake and a lack of physical activity, but also due to genetic factors, the risk for overweight people dying from diseases like coronary heart disease, diabetes und atherosclerosis increases.

29 Aug 2012

MAOA gene appears to make women happy

A new study has found a gene that appears to make women happy, but it doesn't work for men. The finding may help explain why women are often happier than men, the research team said.

29 Aug 2012

High doses of vitamin B3 stimulate CEBPE gene, enhance WBCs’ ability to combat staph infections

Cedars-Sinai researchers have found that a common vitamin may have the potential to provide a powerful weapon to fight certain "superbugs," antibiotic-resistant staph infections that health experts see as a threat to public health.

28 Aug 2012

Friedreich Ataxia Research Alliance, USF ARC to host ‘Understanding a Cure’ symposium

Scientists, clinicians and patients will gather at the University of South Florida's Center for Advanced Medical Learning and Simulation (CAMLS) in downtown Tampa Sept. 6 to share research insights and energize the search for a cure for Friedreich's ataxia and related disorders.

28 Aug 2012

ABCD4 and CblF proteins responsible for hereditary vitamin B12 deficiency

Vitamin B12 is vital for cell division, the synthesis of red blood cells and the functioning of the nervous system. Unable to produce the vitamin itself, the human body has to obtain it via animal proteins. So far it has been known that on its way into the cell vitamin B12 is absorbed by little organelles, so-called lysosomes. From there, the vitamin enters the cell interior with the aid of the transport protein CblF, which was discovered by the same research team three years ago.

28 Aug 2012

More than 40 plant-based compounds can turn on genes that slow the spread of cancer

More than 40 plant-based compounds can turn on genes that slow the spread of cancer, according to a first-of-its-kind study by a Washington State University researcher.

28 Aug 2012

Control of siRNA could aid regenerative medicine, cancer therapy

Some of the body's own genetic material, known as small interfering RNA (siRNA), can be packaged then unleashed as a precise and persistent technology to guide cell behavior, researchers at Case Western Reserve University report in the current issue of the journal, Acta Biomaterialia.

28 Aug 2012

Allegro Diagnostics announces results from BronchoGen genomic test trial on lung cancer

Allegro Diagnostics today announced that results from its AEGIS (Airway Epithelium Gene Expression In the Diagnosis of Lung Cancer) clinical trials, to determine the accuracy of the BronchoGen genomic test, have been accepted for an oral presentation during the late-breaking abstract session at CHEST 2012 on Tuesday, October 23, 2012 at 4:30 p.m. The abstract will also be published in a supplement of the October 2012 issue of CHEST.

28 Aug 2012

Alder’s initiation of ALD518/BMS-945429 Phase 2 trial triggers $3.5M milestone payment

Alder Biopharmaceuticals Inc. today announced it has received a $3.5 million milestone payment from Bristol-Myers Squibb for the initiation of a Phase 2 clinical trial of ALD518/BMS-945429, an investigational antibody therapeutic that blocks interleukin-6 (IL-6), in Crohn's disease.

28 Aug 2012

Morphotek commences MORAb-004 Phase II metastatic soft tissue sarcoma trial

Morphotek, Inc. announced today that it has commenced a multi-center, Phase II study evaluating the safety and efficacy of MORAb-004 when combined with gemcitabine and docetaxel in the treatment of metastatic soft tissue sarcoma.

28 Aug 2012

BioTime amends license agreement with University of Utah for HyStem technology

BioTime, Inc. announced that the company has amended its license from the University of Utah to expand the field of use for which BioTime is licensed to produce and market products covered by the core patents underlying HyStem technology.

27 Aug 2012

CardioDx completes two-tranche equity financing

CardioDx, Inc., a pioneer in the field of cardiovascular genomic diagnostics, today announced the completion of a $58 million two-tranche equity financing.

27 Aug 2012

New blood test can predict which heart failure patients would benefit from ICDs

A novel blood test that predicts sudden death risk in heart failure patients is set to help physicians decide which patients would benefit from implantable cardioverter defibrillators (ICDs).

27 Aug 2012

Healthy intake of micronutrients may boost sperm DNA quality in older men

A new study led by scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) found that a healthy intake of micronutrients is strongly associated with improved sperm DNA quality in older men.

27 Aug 2012

Profilin-1 gene influences survival time in Lou Gehrig's disease

A team of scientists, including faculty at the University of Massachusetts Medical School (UMMS), have discovered a gene that influences survival time in amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).

27 Aug 2012

People with guanine version of rs55705857 SNP more likely to develop gliomas

People who carry a "G" instead of an "A" at a specific spot in their genetic code have roughly a six-fold higher risk of developing certain types of brain tumors, a Mayo Clinic and University of California, San Francisco study has found. The

27 Aug 2012

New molecular mechanism plays a crucial role in inhibiting TGF-beta signaling

Researchers headed by Maria Macias an ICREA researcher at the Institute for Research in Biomedicine (IRB Barcelona) and Joan Massagu-, a Howard Hughes Medical Institute investigator at Memorial Sloan-Kettering Cancer Center (MSKCC) in New York, have identified a new molecular mechanism that plays a crucial role in the control of the activation of certain genes associated with cancer.

27 Aug 2012

Gene News and Research

Latest Gene News and Research

Study shows molecular mechanism behind type 3c pancreatic diabetes

Genetic investigation of tribes may explain why East Asians have lower skin cancer rates

FISH assay identifies only few lung cancer patients who could benefit from crizotinib

Scientists decode signals that boost the burning of fat

MAOA gene appears to make women happy

High doses of vitamin B3 stimulate CEBPE gene, enhance WBCs’ ability to combat staph infections

Friedreich Ataxia Research Alliance, USF ARC to host ‘Understanding a Cure’ symposium

ABCD4 and CblF proteins responsible for hereditary vitamin B12 deficiency

More than 40 plant-based compounds can turn on genes that slow the spread of cancer

Control of siRNA could aid regenerative medicine, cancer therapy

Allegro Diagnostics announces results from BronchoGen genomic test trial on lung cancer

Alder’s initiation of ALD518/BMS-945429 Phase 2 trial triggers $3.5M milestone payment

Morphotek commences MORAb-004 Phase II metastatic soft tissue sarcoma trial

BioTime amends license agreement with University of Utah for HyStem technology

CardioDx completes two-tranche equity financing

New blood test can predict which heart failure patients would benefit from ICDs

Healthy intake of micronutrients may boost sperm DNA quality in older men

Profilin-1 gene influences survival time in Lou Gehrig's disease

People with guanine version of rs55705857 SNP more likely to develop gliomas

New molecular mechanism plays a crucial role in inhibiting TGF-beta signaling

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