Gene News and Research

Latest Gene News and Research

Proteonomix enters license agreement for new anti-tumor technology

Proteonomix, Inc., a biotechnology company focused on developing therapeutics based upon the use of human cells and their derivatives, today announced that it has entered into an exclusive worldwide license agreement for a novel source of primary human cells that secrete a factor capable of inhibiting tumor cell growth and causing tumor cell death.

23 Aug 2012

New results describe development of DC cancer vaccine with enhanced immunogenic potential

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, and collaborators at Radboud University Nijmegen Medical Centre in the Netherlands announced today that they have published new pre-clinical results in the journal Cancer Immunology Immunotherapy describing the development of a dendritic cell (DC) cancer vaccine with enhanced immunogenic potential.

23 Aug 2012

Laminin-111 protein therapy could treat Duchenne muscular dystrophy

A novel treatment in development at the University of Nevada School of Medicine for the most common form of muscular dystrophy is advancing towards human trials with a $308,000 boost from the Muscular Dystrophy Association.

23 Aug 2012

NIH awards $100,000 STTR Phase I Grant to Transgenomic for pancreatic cancer research

Transgenomic, Inc. today announced it has been awarded a $100,000 Small Business Technology Transfer Program (STTR) Phase I Grant by the National Institutes of Health's National Center For Advancing Translational Sciences.

23 Aug 2012

TREM-1 gene disrupts inflammatory process implicated in liver cancer

Researchers at the Georgia Health Sciences University Cancer Center have identified a gene that disrupts the inflammatory process implicated in liver cancer.

23 Aug 2012

Blood cells returned to stem cell state by Johns Hopkins researchers

Johns Hopkins scientists have developed a reliable method to turn the clock back on blood cells, restoring them to a primitive stem cell state from which they can then develop into any other type of cell in the body.

22 Aug 2012

RNA switches can better equip and regulate viruses for many therapeutic applications

Numerous viruses are used in the service of science today. They serve as gene taxis to transfer therapeutic genes into body cells or as therapeutic viruses targeted to infect and destroy cancer cells. For such applications, the viruses are often equipped with additional genes, such as for immune mediators or for proteins inducing programmed cell death. However, these gene products can harm the body if they are released at the wrong moment or at excessive levels.

22 Aug 2012

Acai supplementation could protect against oxidative stress and triple flies' lifespans

Bewildered by the array of antioxidant fruit juices on display in the supermarket and the promises they make? To sort out the antioxidant properties of fruits and berries, scientists at Emory University School of Medicine turned to fruit flies for help.

22 Aug 2012

Researchers report how Alzheimer's protein deposits disrupt signalling between nerve cells

How abnormal protein deposits in the brains of Alzheimer's patients disrupt the signalling between nerve cells has now been reported by researchers in Bochum and Munich, led by Dr. Thorsten M-ller from the Medizinisches Proteom-Center of the Ruhr-Universit-t, in the journal Molecular and Cellular Proteomics. They varied the amount of APP protein and related proteins associated with Alzheimer's disease in cell cultures, and then analysed how this manipulation affected other proteins in the cell.

22 Aug 2012

SSEA4+ marker helps identify and isolate precursors of insulin-producing pancreatic cells

For the millions of people worldwide with type 1 diabetes who cannot produce sufficient insulin, the potential to transplant insulin-producing cells could offer hope for a long-term cure. The discovery of a marker to help identify and isolate stem cells that can develop into insulin-producing cells in the pancreas would be a critical step forward and is described in an article in BioResearch Open Access, a new bimonthly peer-reviewed open access journal from Mary Ann Liebert, Inc.

22 Aug 2012

Study on sea lamprey may indicate how potentially deleterious genes can be controlled

Research on a unique vertebrate called the sea lamprey shows that more than a thousand genes are shed during its early development.

22 Aug 2012

Mof protein plays a key role in epigenetics of stem cells

How do stem cells preserve their ability to become any type of cell in the body? And how do they "decide" to give up that magical state and start specializing? If researchers could answer these questions, our ability to harness stem cells to treat disease could explode. Now, a University of Michigan Medical School team has published a key discovery that could help that goal become reality.

22 Aug 2012

Investigators discover biological explanation for why low levels of oxygen advance SMA symptoms

Investigators at Nationwide Children's Hospital may have discovered a biological explanation for why low levels of oxygen advance spinal muscular atrophy (SMA) symptoms and why breathing treatments help SMA patients live longer. The findings appear in Human Molecular Genetics.

22 Aug 2012

Genetic key to severe malaria resistance uncovered

Researchers have identified two genetic variants linked with human resistance to severe malaria.

21 Aug 2012

Gene therapy applied to peripheral arterial disease

Hepatocyte growth factor gene therapy could be used to treat patients with severe peripheral arterial disease, suggest results of a phase I clinical trial.

21 Aug 2012

New silicon chips help identify patients with lupus

Researchers at the Stanford University School of Medicine and Intel Corp. have collaborated to synthesize and study a grid-like array of short pieces of a disease-associated protein on silicon chips normally used in computer microprocessors.

21 Aug 2012

Dogs offer excellent animal model for human obsessive compulsive disorder study

The genetics research group, based at the University of Helsinki and the Folkh-lsan Research Center and led by Professor Hannes Lohi, has in collaboration with an international group of researchers investigated the characteristics and environmental factors associated with compulsive tail chasing in dogs.

21 Aug 2012

Study utilizes integrative approach to probe biology of bipolar disorder

The more that we understand the brain, the more complex it becomes. The same can be said about the genetics and neurobiology of psychiatric disorders. For "Mendelian" disorders, like Huntington disease, mutation of a single gene predictably produces a single clinical disorder, following relatively simple genetic principals. Compared to Mendelian disorders, understanding bipolar disorder has been extremely challenging. Its biology is not well understood and its genetics are complex.

21 Aug 2012

Lack of certain gene occurs in almost 28% of breast cancers

More than one out of every four cases of breast cancer is associated with a specific, missing gene - a finding that could have significant implications for chemotherapy treatments, according a recent study by Cornell University researchers.

20 Aug 2012

Agilent awarded patent for comparative genomic hybridization methods

Agilent Technologies Inc. today announced that it was awarded a significant patent for comparative genomic hybridization methods. CGH methods help researchers study genetics and cancer in both basic and clinical research.

20 Aug 2012

Gene News and Research

Latest Gene News and Research

Proteonomix enters license agreement for new anti-tumor technology

New results describe development of DC cancer vaccine with enhanced immunogenic potential

Laminin-111 protein therapy could treat Duchenne muscular dystrophy

NIH awards $100,000 STTR Phase I Grant to Transgenomic for pancreatic cancer research

TREM-1 gene disrupts inflammatory process implicated in liver cancer

Blood cells returned to stem cell state by Johns Hopkins researchers

RNA switches can better equip and regulate viruses for many therapeutic applications

Acai supplementation could protect against oxidative stress and triple flies' lifespans

Researchers report how Alzheimer's protein deposits disrupt signalling between nerve cells

SSEA4+ marker helps identify and isolate precursors of insulin-producing pancreatic cells

Study on sea lamprey may indicate how potentially deleterious genes can be controlled

Mof protein plays a key role in epigenetics of stem cells

Investigators discover biological explanation for why low levels of oxygen advance SMA symptoms

Genetic key to severe malaria resistance uncovered

Gene therapy applied to peripheral arterial disease

New silicon chips help identify patients with lupus

Dogs offer excellent animal model for human obsessive compulsive disorder study

Study utilizes integrative approach to probe biology of bipolar disorder

Lack of certain gene occurs in almost 28% of breast cancers

Agilent awarded patent for comparative genomic hybridization methods

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