Gene News and Research

Latest Gene News and Research

New kind of on-off switch for cortisol release in the brain discovered

After we sense a threat, our brain center responsible for responding goes into gear, setting off a chain of biochemical reactions leading to the release of cortisol from the adrenal glands.

23 Feb 2012

Researchers discover how mTOR protein leads to cancer metastasis

Uncovering the network of genes regulated by a crucial molecule involved in cancer called mTOR, which controls protein production inside cells, researchers at the University of California, San Francisco (UCSF) have discovered how a protein "master regulator" goes awry, leading to metastasis, the fatal step of cancer.

23 Feb 2012

Study examines abdomyosarcoma growth in mouse models of muscular dystrophy

Inflammation, cell division and cell differentiation that occur during skeletal muscle regeneration may provide an ideal environment for the highly malignant tumor, rhabdomyosarcoma to arise. These are the findings from a Nationwide Children's Hospital study that examined rhabdomyosarcoma growth in mouse models of muscular dystrophy.

23 Feb 2012

High Court extends time allocated for health law arguments

The Supreme Court on Tuesday added an extra 30 minutes to the time provided for oral arguments, bumping up the total to six hours over three days.

23 Feb 2012

Insight into relationship between two types of suppressors in cancerous tumors

The University of Kentucky has announced that Dr. Daret St. Clair, the James Graham Brown Endowed Chair and professor of toxicology, has published the first comprehensive study that provides insight into the relationship between two types of suppressors in cancerous tumors. The results will enhance the understanding of transcriptional mechanisms in carcinogenesis.

23 Feb 2012

Targeting versican protein may help stop breast cancer metastasis

Oncologists have known that in order for cancer cells to spread, they must transform themselves so they can detach from a tumor and spread to a distant organ. Now, scientists at Weill Cornell Medical College have revealed critical steps in what happens next -- how these cells reverse the process, morphing back into classical cancer that can now grow into a new tumor.

23 Feb 2012

People with celiac disease are at risk for osteoporosis

People with celiac disease are at risk for osteoporosis, according to physicians at Loyola University Health System (LUHS). A 2009 New England Journal of Medicine study supports this correlation. Researchers believe that people with celiac disease may develop osteoporosis because their body poorly absorbs calcium and vitamin D, which are necessary for bone health.

22 Feb 2012

Routine hepatitis C testing of the middle aged could save thousands of lives: CDC report

Increasing number of people are dying of damaged livers due to hepatitis C infection. Federal health officials are considering whether anyone born between 1945 and 1965 should get a one-time blood test to check if they are harboring the dangerous virus. Two-thirds of people with hepatitis C are in this age group, most unaware that a virus that takes a few decades to do its damage has festered since their younger days.

22 Feb 2012

Study on role of genetics and environmental influences on criminal and antisocial behavior

An assistant professor at Sam Houston State University, College of Criminal Justice is working to unlock the mysteries surrounding the role that genetics and environmental influences play on criminal and antisocial behavior.

22 Feb 2012

Study reveals how mutation shuts down DJ-1 protein's neuroprotective abilities

Purdue University researchers revealed how a mutation in a protein shuts down a protective function needed to prevent the death of neurons in Parkinson's disease, possibly opening the door to new drug strategies to treat the disorder.

22 Feb 2012

Mitochondria may be promising new target for cancer treatment

Mitochondria, tiny structures within each cell that regulate metabolism and energy use, may be a promising new target for cancer therapy, according to a new study. Manipulation of two biochemical signals that regulate the numbers of mitochondria in cells could shrink human lung cancers transplanted into mice, a team of Chicago researchers report in the journal FASEB.

22 Feb 2012

Researchers study specially bred mice to understand annual flu epidemics

As part of a national collaboration, Oregon Health & Science University researchers are studying specially bred mice that are more like humans than ever before when it comes to genetic variation. Through these mice, the researchers hope to better understand and treat an infectious disease that plagues us year in and year out: the flu.

22 Feb 2012

IDOM researchers overturn textbook view of liver metabolism

A team led by researchers from the Institute for Diabetes, Obesity and Metabolism (IDOM) at the Perelman School of Medicine, University of Pennsylvania, has overturned a "textbook" view of what the body does after a meal.

22 Feb 2012

AChemS recognizes Monell Center molecular biologist as outstanding junior scientist

Molecular biologist Ichiro Matsumoto, Ph.D., of the Monell Center, is the recipient of the 2012 Ajinomoto Award for Young Investigators in Gustation, awarded annually by the Association for Chemoreception Sciences (AChemS) to an outstanding junior scientist who is an emerging leader in the field of gustation.

22 Feb 2012

Key regulator of lens development also controls mechanosensory neuron development

A gene known to control lens development in mice and humans is also crucial for the development of neurons responsible for mechanosensory function, as neurobiologists of the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch have now discovered.

22 Feb 2012

FDA grants orphan-drug designation to Arno's AR-42 for treatment of meningioma, schwannoma

Arno Therapeutics, Inc. announced today that its investigational compound, AR-42, has been granted orphan-drug designation by the U.S. Food and Drug Administration for the treatment of meningioma and schwannoma of the central nervous system.

21 Feb 2012

Tasmanian devil cancer genome mapped

Researchers, including those from Wellcome Trust Sanger Institute near Cambridge, have sequenced the genome of a facial cancer that is threatening the existence of the Tasmanian devil.

21 Feb 2012

Biotech company defends patent on gene mutation for breast cancer

A US biotechnology company is defending the granting of a controversial patent over a common genetic mutation for breast cancer, rejecting accusations it amounts to the privatization of the human body.

21 Feb 2012

Genomic instability allows malignant cells to acquire more deadly characteristics

Genomic instability caused by an erosion of the protective caps on chromosomes, followed by activation of an enzyme that reinforces those aps, allows malignant cells to evade destruction and acquire more deadly characteristics, researchers report in an Online Now article at the journal Cell.

21 Feb 2012

Precision BioSciences sues Cellectis over engineered meganucleases patent infringement

Precision BioSciences, Inc., a leader in the field of genome engineering, today announced that it has filed two patent infringement lawsuits against Cellectis SA and a number of its affiliates in the U.S. District Court for the Eastern District of North Carolina.

21 Feb 2012

Gene News and Research

Latest Gene News and Research

New kind of on-off switch for cortisol release in the brain discovered

Researchers discover how mTOR protein leads to cancer metastasis

Study examines abdomyosarcoma growth in mouse models of muscular dystrophy

High Court extends time allocated for health law arguments

Insight into relationship between two types of suppressors in cancerous tumors

Targeting versican protein may help stop breast cancer metastasis

People with celiac disease are at risk for osteoporosis

Routine hepatitis C testing of the middle aged could save thousands of lives: CDC report

Study on role of genetics and environmental influences on criminal and antisocial behavior

Study reveals how mutation shuts down DJ-1 protein's neuroprotective abilities

Mitochondria may be promising new target for cancer treatment

Researchers study specially bred mice to understand annual flu epidemics

IDOM researchers overturn textbook view of liver metabolism

AChemS recognizes Monell Center molecular biologist as outstanding junior scientist

Key regulator of lens development also controls mechanosensory neuron development

FDA grants orphan-drug designation to Arno's AR-42 for treatment of meningioma, schwannoma

Tasmanian devil cancer genome mapped

Biotech company defends patent on gene mutation for breast cancer

Genomic instability allows malignant cells to acquire more deadly characteristics

Precision BioSciences sues Cellectis over engineered meganucleases patent infringement

eBook: Using iPSCs models for human disease research and drug discovery eBook

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Automating research - solutions and best practices

How can microdialysis benefit drug development