Gene News and Research

Latest Gene News and Research

Scientists overcome major challenge in gene therapy and drug delivery

Imagine trying to poke a hole in the yolk of a raw egg without breaking the egg white. It sounds impossible, but researchers at the University of California San Diego have developed a technology that performs a similarly delicate task in living cells. They created an array of nanopillars that can breach the nucleus of a cell-;the compartment that houses our DNA-;without damaging the cell's outer membrane.

3 Oct 2024

Study highlights the role of genetic factors in COVID-19 thrombosis and inflammation

Despite global vaccination efforts, COVID-19 continues to pose significant risks, leading to severe complications and fatalities. These risks are driven by disrupted coagulation, impaired fibrinolysis, which is the process of breaking blood clots, and heightened inflammatory responses.

3 Oct 2024

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

Researchers used stem-cell derived organoids from Crohn's disease patients to identify two molecular subtypes, paving the way for personalized treatments targeting specific disease characteristics.

2 Oct 2024

CheekAge can accurately predict the risk of mortality, study shows

We don't all age at the same rate. But while some supercentenarians may age exceptionally slowly due to winning the genetics jackpot, a plethora of behavioral and lifestyle factors are known to speed up aging, including stress, poor sleep, poor nutrition, smoking, and alcohol.

1 Oct 2024

Genetic study uncovers key drivers of metabolic syndrome with brain tissue links

Researchers uncovered 1,307 genetic loci linked to metabolic syndrome, revealing brain tissue enrichment and key genetic factors in its development. The study also shows polygenic risk scores predict metabolic syndrome across populations.

1 Oct 2024

Epigenetic hallmarks of cancer unveiled in new research

Cancer mortality has just surpassed cardiovascular disease for the first time ever and one in two men, and one in three women, will be diagnosed with some form of the disease in the US, according to the NIH.

1 Oct 2024

New insights improve genetic classification for hereditary colorectal cancer

The genetic confirmation of a suspected diagnosis of "hereditary colorectal cancer" is of great importance for the medical care of affected families.

1 Oct 2024

New humanized mouse models created to study COVID-19

Scientists at La Jolla Institute for Immunology (LJI) have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19.

1 Oct 2024

The role of FOXM1 and PD-L1 in malignant peripheral nerve sheath tumor resistance

A new mini review was published in Oncotarget's Volume 15 on September 30, 2024, entitled, "Linking FOXM1 and PD-L1 to CDK4/6-MEK targeted therapy resistance in malignant peripheral nerve sheath tumors."

1 Oct 2024

Novel lipid nanoparticles enhance tissue-specific drug delivery

Penn Engineers have discovered a novel means of directing lipid nanoparticles (LNPs), the revolutionary molecules that delivered the COVID-19 vaccines, to target specific tissues, presaging a new era in personalized medicine and gene therapy.

1 Oct 2024

Unlocking the secrets of analytical services: An insider interview with colman byrne

In this interview, News-Medical talks to Mr. Byrne about the crucial role of analytical services.

From DSI, a PLG Company 1 Oct 2024

Combining apple peel and mistletoe extracts to boost muscle health and endurance

Research shows that mistletoe and apple peel extracts improve muscle health and endurance, suggesting a natural approach to combat age-related muscle decline.

1 Oct 2024

Iron retention in skin linked to psoriasis: Could hepcidin be the missing piece in treatment?

This study reveals hepcidin's significant role in psoriasis, linking iron retention to inflammation and keratinocyte growth, suggesting new therapeutic targets.

1 Oct 2024

ERS Genomics and Université de Montréal sign CRISPR/Cas9 license agreement

Université de Montréal gains access to ERS Genomics' CRISPR/Cas9 patents, launching platforms for genome-wide screening and fostering research collaborations.

From ERS Genomics 1 Oct 2024

Researchers uncover new disease-linked microbial species through pan-body microbiome analysis

Researchers in Germany conducted a pan-body microbiome analysis, uncovering new microbial species and potential therapies linked to diseases, with implications for diagnostic and therapeutic advancements.

1 Oct 2024

Scientists uncover role of Wnt in kidney formation

A group of essential signaling molecules known as the Wnt pathway emerged early in the evolution of multicellular life. Scientists have been studying Wnt actions for four decades to comprehend its complex roles in development and disease.

1 Oct 2024

NIH grant supports research on cognitive decline in individuals with Lewy body diseases

Penn Medicine researchers will advance their understanding of the underlying causes of cognitive decline in individuals with Lewy body diseases, like Parkinson's, and identify biomarkers that predict which individuals are more likely to develop dementia with a $18 million grant from the National Institutes of Health/National Institute on Aging.

30 Sep 2024

Advanced brain mapping reveals neuronal subtypes and their connections

Scientists at the Salk Institute are unveiling a new brain-mapping neurotechnology called Single Transcriptome Assisted Rabies Tracing (START). The cutting-edge tool combines two advanced technologies-;monosynaptic rabies virus tracing and single-cell transcriptomics-;to map the brain's intricate neuronal connections with unparalleled precision.

30 Sep 2024

Two genetic variants linked to Alzheimer's trigger microglial inflammation in females

Weill Cornell Medicine investigators have found that two genetic variants that confer high risk of Alzheimer's disease (AD) together trigger a harmful inflammatory response in the brain's immune cells, particularly in females, in a preclinical model.

30 Sep 2024

New genetic syndrome bridges the gap between neurodevelopmental and neurodegenerative disorders

In a landmark discovery, researchers from the University of Antioquia have identified a new genetic syndrome that bridges the gap between neurodevelopmental disorders and neurodegenerative diseases.

30 Sep 2024

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Gene News and Research

Latest Gene News and Research

Scientists overcome major challenge in gene therapy and drug delivery

Study highlights the role of genetic factors in COVID-19 thrombosis and inflammation

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

CheekAge can accurately predict the risk of mortality, study shows

Genetic study uncovers key drivers of metabolic syndrome with brain tissue links

Epigenetic hallmarks of cancer unveiled in new research

New insights improve genetic classification for hereditary colorectal cancer

New humanized mouse models created to study COVID-19

The role of FOXM1 and PD-L1 in malignant peripheral nerve sheath tumor resistance

Novel lipid nanoparticles enhance tissue-specific drug delivery

Unlocking the secrets of analytical services: An insider interview with colman byrne

Combining apple peel and mistletoe extracts to boost muscle health and endurance

Iron retention in skin linked to psoriasis: Could hepcidin be the missing piece in treatment?

ERS Genomics and Université de Montréal sign CRISPR/Cas9 license agreement

Researchers uncover new disease-linked microbial species through pan-body microbiome analysis

Scientists uncover role of Wnt in kidney formation

NIH grant supports research on cognitive decline in individuals with Lewy body diseases

Advanced brain mapping reveals neuronal subtypes and their connections

Two genetic variants linked to Alzheimer's trigger microglial inflammation in females

New genetic syndrome bridges the gap between neurodevelopmental and neurodegenerative disorders

eBook: Using iPSCs models for human disease research and drug discovery eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production