Gene News and Research

Latest Gene News and Research

Study reveals positive correlation between type 2 immunity and long-term cancer remission

Results from a preclinical study in mice, led by EPFL, and a collaborative clinical study in patients show that the type 2 immune response – associated with parasitic infection and thought to play a negative role in cancer immunity – is positively correlated with long-term cancer remission.

26 Sep 2024

Genetic factors that make the bacteria behind cholera so dangerous uncovered

Study reveals key genetic factors in Vibrio cholerae O1 that drive cholera transmission and severity, highlighting targets for novel therapeutic strategies.

26 Sep 2024

Targeted drug therapy shows promise for ulcerative colitis remission

An international placebo-controlled study led by Cedars-Sinai suggests that a targeted drug therapy that was developed by researchers at Cedars-Sinai is safe and effective at helping people with moderate to severe ulcerative colitis reach clinical remission.

26 Sep 2024

Why children with Down’s syndrome are predisposed to developing leukaemia

The study uncovers mechanisms linking Down syndrome to leukemia, emphasizing the role of oxidative stress and genetic alterations in fetal blood development.

26 Sep 2024

Targeting tumor immunity with transferrin receptor-directed photodynamic therapy

This new article publication from Acta Pharmaceutica Sinica B, discusses a transferrin receptor-targeted immunostimulant for photodynamic immunotherapy against metastatic tumors through β-catenin/CREB interruption.

26 Sep 2024

Centenarians' stem cells unlock secrets to healthy aging

Individuals who display exceptional longevity provide evidence that humans can live longer, healthier lives.

25 Sep 2024

Study reveals life-changing impact of gene therapy for hemophilia B patients

Adults with hemophilia B saw their number of bleeding episodes drop by an average of 71 percent after a single infusion of gene therapy, according to the results of an international Phase III clinical trial published today in the New England Journal of Medicine by researchers from the University of Pennsylvania Perelman School of Medicine and a multicenter group of investigators.

25 Sep 2024

Breakthrough research offers hope for improved treatment of chronic wounds

Novel research, presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2024, has identified key molecular targets that could significantly enhance the healing of both acute and chronic wounds.

25 Sep 2024

H5N1 bird flu is mutating fast and jumping to mammals - could the next pandemic be here?

Researchers reveal how H5N1 viruses rapidly adapted to mammals through genetic reassortment and specific mutations, raising concerns over potential pandemic risks. Evidence from mink, marine mammals, and dairy cattle shows mammal-to-mammal transmission.

25 Sep 2024

New AI tool revolutionizes drug discovery for rare diseases

There are more than 7,000 rare and undiagnosed diseases globally.

25 Sep 2024

CRISPR-Cas13 emerges as a game changer in RNA-targeted therapies

In recent years, the scientific community has made significant strides in the field of gene editing, particularly through the development of the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) systems.

25 Sep 2024

New deep learning algorithm predicts effects of rare genetic variants

Whether we are predisposed to particular diseases depends to a large extent on the countless variants in our genome.

25 Sep 2024

Researchers gain new understanding of how immune cells respond to heat during fever

The study reveals that moderate fever enhances CD4 T cell activity while reducing regulatory T cell suppression, highlighting temperature's immune effects.

25 Sep 2024

The potential to optimize laboratory testing and operations with automation and AI

In this interview, NewsMedical speaks with Cerba's Coen Staplers about the benefits of lab automation, including the integration of AI technologies.

From Cerba Research 25 Sep 2024

New FDA award fuels research into autosomal dominant tubulointerstitial kidney disease

Critical Path Institute (C-Path) is thrilled to announce its Polycystic Kidney Disease Outcomes Consortium (PKDOC) has been awarded an Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD) focused Broad Agency Announcement (BAA) contract from the U.S. Food and Drug Administration (FDA).

24 Sep 2024

Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies

Research connects gut microbiota to lupus and IBD, uncovering microbial markers and pathways that could inform targeted therapies for autoimmune disorders.

24 Sep 2024

Known genes account for most undiagnosed cases of developmental disorders

Scientists have conducted the largest and most diverse study to date on how recessive genetic changes contribute to developmental disorders. They found that most undiagnosed cases that are due to recessive causes are linked to genes we already know about, and suggest a shift in research focus could improve diagnosis rates.

24 Sep 2024

Groundbreaking project seeks to illuminate the complexities of Parkinson's

Launching today, Landmark is a groundbreaking three-year research programme that aims to understand Parkinson’s in unprecedented detail. The project brings together Parkinson’s UK, Imperial College London, GSK, Novartis, Roche and UCB for the first time, and has been made possible by a founding gift of £4 million from the Gatsby charitable foundation.

24 Sep 2024

New drug combo shows promise for deeper remission in chronic leukemia

Researchers leading the SWOG S1712 clinical trial have found that adding ruxolitinib to standard tyrosine kinase inhibitor (TKI) treatment for patients with chronic-phase chronic myeloid leukemia (CP-CML) significantly increased the percentage of patients who had a molecular response deep enough to warrant discontinuing treatment.

24 Sep 2024

Wastewater surveillance detects influenza and H5 viruses from human and animal sources

Wastewater surveillance reveals influenza A and H5 subtype detections, providing critical insights into public health risks from both human and animal sources during the ongoing HPAI A(H5N1) outbreak.

24 Sep 2024

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Gene News and Research

Latest Gene News and Research

Study reveals positive correlation between type 2 immunity and long-term cancer remission

Genetic factors that make the bacteria behind cholera so dangerous uncovered

Targeted drug therapy shows promise for ulcerative colitis remission

Why children with Down’s syndrome are predisposed to developing leukaemia

Targeting tumor immunity with transferrin receptor-directed photodynamic therapy

Centenarians' stem cells unlock secrets to healthy aging

Study reveals life-changing impact of gene therapy for hemophilia B patients

Breakthrough research offers hope for improved treatment of chronic wounds

H5N1 bird flu is mutating fast and jumping to mammals - could the next pandemic be here?

New AI tool revolutionizes drug discovery for rare diseases

CRISPR-Cas13 emerges as a game changer in RNA-targeted therapies

New deep learning algorithm predicts effects of rare genetic variants

Researchers gain new understanding of how immune cells respond to heat during fever

The potential to optimize laboratory testing and operations with automation and AI

New FDA award fuels research into autosomal dominant tubulointerstitial kidney disease

Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies

Known genes account for most undiagnosed cases of developmental disorders

Groundbreaking project seeks to illuminate the complexities of Parkinson's

New drug combo shows promise for deeper remission in chronic leukemia

Wastewater surveillance detects influenza and H5 viruses from human and animal sources

eBook: Using iPSCs models for human disease research and drug discovery eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production