Gene News and Research

Latest Gene News and Research

$74 million allocated to study environmental causes of disease

As part of the new Exposure Biology Program, the National Institute of Environmental Health Sciences, a component of the National Institutes of Health, today announced $74 million in grant opportunities for the development of new technologies that will improve the measurement of environmental exposures that contribute to human disease.

19 Oct 2006

FDA advisory panel recommends adding warning label to Tamoxifen

An FDA advisory panel on Wednesday recommended that a warning label be added to tamoxifen, an agency-approved drug for treating and preventing breast cancer, the AP/Seattle Post-Intelligencer reports (Bridges, AP/Seattle Post-Intelligencer, 10/18).

19 Oct 2006

Co-delivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer

Efforts to treat cancer using genes and other oligonucleotides, such as short interfering RNA (siRNA), that turn off the biochemical processes that trigger malignancies have been hindered by difficulties in delivering nucleic acids to tumors.

16 Oct 2006

A nanoplasmonic molecular ruler for measuring nuclease activity and DNA footprinting

The interactions between proteins and nucleic acids play a critical role in some of life’s most crucial biochemical processes, including gene expression and protein production, and some promising anticancer agents exert their effects by interfering with these interactions.

16 Oct 2006

National Eye Institute to finance two-year study comparing effectiveness of treatments for macular degeneration

The National Eye Institute on Thursday said it will finance a two-year study comparing the effectiveness of Genentech's eye treatment Lucentis and cancer drug Avastin for treating wet age-related macular degeneration, the New York Times reports.

8 Oct 2006

FDA approves test to help diagnose HIV

The U.S. Food and Drug Administration (FDA) has approved the APTIMA HIV-1 RNA Qualitative Assay, manufactured by Gen-Probe Incorporated (San Diego, Calif.).

5 Oct 2006

FDA more cautious in approving new drugs after Vioxx

Many pharmaceutical companies and industry observers say that FDA is "quietly becoming more assertive about keeping new drugs off the market or refusing to approve new uses for existing medications" in response to criticism since the 2004 Vioxx recall, the New York Times reports.

3 Oct 2006

Food like an addictive drug for some people

Researchers in the U.S. have found that the same brain circuits are involved when obese people fill their stomachs as when drug addicts think about drugs and the discovery they say suggests an association between overeating and addiction.

3 Oct 2006

Research implicates brain circuits involved in drug craving and emotional response to food

Researchers at the U.S. Department of Energy's Brookhaven National Laboratory have found new clues to how the brain and the stomach interact with emotions to cause overeating and obesity.

2 Oct 2006

Faulty gene linked to hair pulling disorder

An unusual and uncommon psychiatric disorder that compels people to pull out their hair is now thought to be caused by a mutant gene.

27 Sep 2006

SUMO1 gene implicated in cleft lip and palate defects

Researchers supported by the National Institutes of Health report in the current issue of the journal Science that a much-studied gene called SUMO1, when under expressed, can cause cleft lip and palate, one of the world's most common birth defects.

21 Sep 2006

New understanding of how cells defend themselves

Biologists at the EPFL (Ecole Polytechnique Federale de Lausanne) have unveiled a new twist in a metabolic pathway that cells use to defend themselves against toxins made by disease-causing bacteria.

21 Sep 2006

Insulin receptor stops progression of Alzheimer's disease

Stimulation of a receptor in the brain that controls insulin responses has been shown to halt or diminish the neurodegeneration of Alzheimer's disease, providing evidence that the disease can be treated in its early stages, according to a study by researchers at Rhode Island Hospital and Brown Medical School.

21 Sep 2006

Direct observations of DNA provides new insights into how genetic material is copied and repaired

"We can monitor the process directly, and that gives us a different perspective," said Roberto Galletto, a postdoctoral scholar at UC Davis and first author on a paper published Sept. 20 on the Web site of the journal Nature.

21 Sep 2006

New target for cancer therapy identified by Australian researchers

A new target for cancer therapy has been identified by Monash University scientists investigating the cell signalling pathways that turn on a gene involved in cancer development.

21 Sep 2006

Leptin could combat type 2 diabetes

University of Florida researchers have discovered the appetite-controlling hormone leptin could also combat type 2 diabetes, a disease that has become a growing problem in the United States as more Americans pack on extra pounds.

21 Sep 2006

Researchers discover clues to the cause of T-cell acute lymphoblastic leukemia

Researchers' discovery of clues to the cause of T-cell acute lymphoblastic leukemia (T-ALL) - a form of pediatric cancer that has a very poor prognosis - could lead to the development of new targeted therapies for this extremely difficult disease.

20 Sep 2006

Nanocantilever biosensors detect multiple genes

Using nanoscale cantilevers in a microfluidics device, a team of European researchers has developed a portable biosensor capable of detecting specific genetic sequences.

19 Sep 2006

Racial discrimination can affect adolescents' development - lead to depression and behavior problems

Racial discrimination in the lives of African-American children can lead to depression and behavior problems in adolescence, but teens who have had close relationships with their parents, friendships focused on positive pursuits and good schooling experiences are less likely to experience these negative effects.

14 Sep 2006

Study extends the number of antigenic peptides that can be produced from a single protein

Understanding medical research problems often relies on the direct, linear relationship between the sequence of a protein and the DNA encoding that protein. In fact, colinearity of DNA and protein sequences is thought to be a fundamental feature of the universal genetic code.

13 Sep 2006

Gene News and Research

Latest Gene News and Research

$74 million allocated to study environmental causes of disease

FDA advisory panel recommends adding warning label to Tamoxifen

Co-delivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer

A nanoplasmonic molecular ruler for measuring nuclease activity and DNA footprinting

National Eye Institute to finance two-year study comparing effectiveness of treatments for macular degeneration

FDA approves test to help diagnose HIV

FDA more cautious in approving new drugs after Vioxx

Food like an addictive drug for some people

Research implicates brain circuits involved in drug craving and emotional response to food

Faulty gene linked to hair pulling disorder

SUMO1 gene implicated in cleft lip and palate defects

New understanding of how cells defend themselves

Insulin receptor stops progression of Alzheimer's disease

Direct observations of DNA provides new insights into how genetic material is copied and repaired

New target for cancer therapy identified by Australian researchers

Leptin could combat type 2 diabetes

Researchers discover clues to the cause of T-cell acute lymphoblastic leukemia

Nanocantilever biosensors detect multiple genes

Racial discrimination can affect adolescents' development - lead to depression and behavior problems

Study extends the number of antigenic peptides that can be produced from a single protein

eBook: Using iPSCs models for human disease research and drug discovery eBook

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology