Gene News and Research

Latest Gene News and Research

Pituitary adenoma predisposition caused by germline mutations in the AIP gene

A recent Finnish study identifies a low-penetrance gene defect which predisposes carriers to intracranial tumors called pituitary adenomas. In particular individuals carrying the gene defect are susceptible to such tumors which secrete growth hormone.

1 Jun 2006

Gene variation linked to more severe Crohn's disease

Building on previous evidence supporting the theory that the pathophysiology of Crohn's Disease is altered by genetic variation, recent studies have found that the combination of immune signals given by three variants of a single candidate gene affects the severity of the disease.

1 Jun 2006

Two specific genes, Wnt4 and Fgf9 fight to determine sexual differentiation

Whether or not a fertilized mammalian egg ultimately develops into a male or female is determined by the winner of a tug of war between two different genes encoding signaling proteins and the divergent pathways they control.

1 Jun 2006

Scientists gain better understanding of Proteus mirabilis

Scientists now have inside information to use in the fight against Proteus mirabilis - a nasty bacterium that can cause kidney stones, as well as hard-to-treat urinary tract infections.

1 Jun 2006

Potential novel treatment strategy for Ewing's sarcoma

Using molecular and cell-based models, researchers at Georgetown University Medical Center have refined the picture of how a cancer-promoting protein associated with Ewing's sarcoma functions.

1 Jun 2006

Cause of neurodegeneration in Huntington's disease discovered

The severe neurodegeneration associated with Huntington's disease may result from molecular mutations that block the transport of nutrients within cells.

1 Jun 2006

Exposure to environmental estrogens during development of the prostate gland in the male fetus may lead to later prostate cancer risk

A study in the June 1 issue of Cancer Research presents the first evidence that exposure to low doses of environmental estrogens during development of the prostate gland in the male fetus may result in a predisposition to prostate cancer later in life.

1 Jun 2006

Study reveals how production of interferon gamma is controlled in natural killer cells

A new study reveals how the production of a potent immune regulator called interferon gamma (IFNg) is controlled in natural killer (NK) cells, immune cells that typically defend the body against cancer and infections.

31 May 2006

Promising new vaccine delivery approach

The field of vaccine development is getting a boost from new research that has identified a promising vaccine delivery approach, which in animal studies produced long-term immune protection after just one immunization.

31 May 2006

Finding opens new pathways for treating or preventing autoimmune diseases

A rare genetic defect that can trigger a host of diseases from type 1 diabetes to alopecia has helped explain the imbalance of immune regulator and killer cells in autoimmune disease.

31 May 2006

How sexy we feel depends on our genes

According to researchers at the Hebrew University of Jerusalem, how sexy we feel depends on our genes.

31 May 2006

Genetic variations impact sexual desire

New evidence that individual differences in human sexual desire can be attributed to genetic variations has been revealed by a research group headed by a professor of psychology at the Hebrew University of Jerusalem.

29 May 2006

EU ruling on breast drug Herceptin will end 'post code lottery' in Britain

The European Union has approved the use of the breast cancer drug Herceptin for use in patients with an early stage of the aggressive HER2-positive type of breast cancer.

24 May 2006

MRI cost-effective for some women at high-risk of breast cancer

A computer model simulation suggests that adding breast MRI screening may be cost-effective for women of certain ages who carry BRCA1 and BRCA2 gene mutations.

23 May 2006

Body has more than one body clock

Research conducted at Oregon Health & Science University suggests that contrary to popular belief, the body has more than one "body clock."

23 May 2006

Gene expression becomes heterogeneous with age

In a study of the effects of aging on gene expression, researchers have found that variation in gene expression among individuals tends to increase with age.

23 May 2006

Cysteine containing tablets and chewing gum potential new way to prevent upper digestive tract cancers

Researchers at the University of Helsinki, Finland, suggest that cysteine containing tablets and chewing gum can be a new way for the prevention of upper digestive tract cancers.

23 May 2006

New technique to deliver insulin genes to pancreas

Researchers at Baylor University Medical Center at Dallas and the Baylor Research Institute have developed a novel technique to deliver insulin genes to the pancreas, the organ that produces the body's insulin.

23 May 2006

Sperm donor passes rare dangerous disease on to four children

According to a new report in the U.S., a sperm donor may have unwittingly passed an extremely rare and dangerous genetic ailment to five children born to four couples.

22 May 2006