Gene News and Research

Latest Gene News and Research

Drug combo may have a greater impact on cancer development

Cancer researchers have long suggested that new targeted drugs may work best when paired with other therapies. In a new study published today in Cancer Research, scientists have taken some of the first steps to demonstrate this synergy in mouse and cell line models.

16 Sep 2004

Newly completed Chromosome 5 sequence will be a powerful tool for scientists trying to understand human disease

Four years after publicly revealing the official draft human genetic sequence, researchers have reached the halfway point in dotting the i's and crossing the t's of the genetic sentences describing how to build a human.

16 Sep 2004

Mighty mouse helps researchers tackle osteoporosis

A genetically engineered 'mighty mouse' is helping Medical College of Georgia researchers find the best way for young people to build bone and avoid osteoporosis.

16 Sep 2004

Role of gene identified in development of tumours in children

Medical researchers from Children’s Cancer Institute Australia for Medical Research (CCIA) have made significant progress in understanding tumour initiation in the aggressive, debilitating childhood cancer, neuroblastoma

14 Sep 2004

Liver cancer genes cluster into two subsets that correlate to survival

An analysis of the gene expression patterns of 91 unrelated liver tumors revealed two distinctive subclasses highly associated with patient survival, according to a new study published in the September 2004 issue of Hepatology.

14 Sep 2004

Genetically modified bacterium as remedy for intestinal diseases

Researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) at Ghent University are joining the fight against chronic intestinal disease with a genetically modified bacterium (Lactococcus lactis).

14 Sep 2004

New genetic test can predict cleft lip or palate

Researchers have developed a new genetic test that can help predict whether parents who have one child with the "isolated" form of cleft lip or palate are likely to have a second child with the same birth defect. Isolated clefts account for 70 percent of all cleft lip and palate cases.

10 Sep 2004

Suprising new information on the HOX genes

Researchers at the University of Bergen are now able to present new information on the HOX genes – the “software” to design animals. The findings are published in today’s issue of Nature.

10 Sep 2004

Cancer drug may reduce kidney disease in lupus

A drug that is already being tested as an anticancer agent, especially in lymphoma, may also reduce the kidney disease that is a result of systemic lupus, according to a researcher at Wake Forest University Baptist Medical Center.

10 Sep 2004

New view of chromatin and gene activity

A genome - the DNA instructions for an organism - does not act alone. DNA is packaged with proteins into 'chromatin', which may be more or less tightly condensed. A popular proposal is that active genes are in 'open' chromatin (to allow access to them) and inactive genes are in tightly packed 'compact' chromatin.

10 Sep 2004

Disruption of protein folding causes neurodegeneration, mental retardation

Excess accumulation in brain cells of a fat molecule called GM1-ganglioside (GM1) disrupts the folding of newly assembled proteins into their proper shapes, triggering nerve degeneration and mental retardation in children.

10 Sep 2004

Missing genes may help explain why plague bacteria are so deadly

What makes the germ that causes plague so fearsomely lethal, while a close relative only produces digestive disorders and is rarely fatal?

10 Sep 2004

MRI most effective for detecting breast cancer for women with breast cancer gene mutations

MRI is more accurate for detecting breast cancer than mammography, ultrasound or clinical breast examination alone, in women who carry the BRCA1 or BRCA2 gene mutation, according to a study in the September 15 issue of JAMA.

10 Sep 2004

Scientists closer to correcting an abnormal gene which causes Charcot-Marie-Tooth disease

Scientists at the University of Edinburgh are closer to correcting an abnormal gene which causes one of the crippling muscle wasting diseases known collectively as Charcot-Marie-Tooth (CMT) disease.

10 Sep 2004

Gene mutations cause 85 percent of colon cancers

Mutations in the adenomatous polyposis coli (APC) tumor suppressor gene have been found to cause 85 percent of colon cancers.

9 Sep 2004

Research crucial in determining what gene mutations might lead to congenital cardiovascular defects

According to the American Heart Association, congenital cardiovascular defects, such as congenital heart disease (CHD), are present in about one percent of live births and are the most common malformations in newborns.

9 Sep 2004

Genetically modified fish may help treat hemophiliacs

A human blood-clotting factor used to treat some people with haemophilia and accident victims suffering serious bleeding has been produced using genetically modified fish.

9 Sep 2004

Gene linked to both alcoholism and depression

A national team of investigators led by psychiatric geneticists at Washington University School of Medicine in St. Louis has identified a gene that appears to be linked to both alcoholism and depression.

8 Sep 2004

Autism may arise from a mixture of sources that include a few genes and epigenetics

Autism, a serious developmental disorder in children, may arise from a mixture of sources that include a few genes and alterations in the factors that regulate genes (epigenetics) that may be inherited or occur as a new event, said researchers from Baylor College of Medicine.

8 Sep 2004

Studies of human genetic variation have found strong evidence for the action of natural selection

One of the most comprehensive studies of the forces that have shaped patterns of human genetic variation has found strong evidence for the action of natural selection, which may help explain why certain people are at risk for a variety of conditions and others are not.

8 Sep 2004