Gene News and Research

Latest Gene News and Research

First evidence of the molecular link between inflammation and cancer

The investigators found that a gene called I-kappa-B kinase (IKK beta), a pro-inflammatory gene, acts differently in two cell types to cause cancer. When IKK beta was deleted, the cancer incidence and tumor growth in mice was decreased by nearly 80 percent.

5 Aug 2004

New gene-silencing technique

A new gene-silencing technique that takes place in the nucleus of human cells, has been demonstrated by researchers at the University of California, San Diego (UCSD) School of Medicine and the VA San Diego Healthcare System.

5 Aug 2004

Protein loss plays role in acute T-cell leukemia

The loss of a key protein (Smad3) in a pathway that helps prevent tumors from forming is specific to one form of childhood leukemia, but not to other pediatric and adult forms of leukemia, according to a new study published in the August 5, 2004, New England Journal of Medicine.

5 Aug 2004

Successfully cloning mice from an advanced melanoma cell

Nature can reset the clock in certain types of cancer and reverse many of the elements responsible for causing malignancy, reports a research team led by Whitehead Institute Member Rudolf Jaenisch, in collaboration with Lynda Chin from Dana Farber Cancer Institute.

3 Aug 2004

Mothers who catch a flu during pregnancy may increase the risk of their child developing schizophrenia

Schizophrenia is a chronic, severe, and disabling brain disease. Approximately 1 percent of the population develops schizophrenia during their lifetime — more than 2 million Americans suffer from the illness in a given year.

3 Aug 2004

New gene therapy treatment involves injecting Herpes simplex virus into the brain tumours of Glioma patients

Experts on the Gene Therapy Advisory Committee have given the go ahead for a large clinical trial of a new treatment for patients with Glioma - one of the most aggressive types of brain tumours for which there is currently no cure.

3 Aug 2004

Entirely new approach to the treatment of aging

Dispelling the belief that the only way to treat such conditions is by fixing or replacing damaged genes, they instead focused on the field of epigenetics—the study of changes in gene silencing that occur without changes in the genes themselves.

3 Aug 2004

New Drug Application with the U.S. Food and Drug Administration for Tarceva

OSI Pharmaceuticals and Genentech have announced that OSI completed the submission of a New Drug Application with the U.S. Food and Drug Administration for Tarceva (erlotinib HCl),

3 Aug 2004

New screening technique to look for genes that change patients' responses to cancer drugs and other medications

Scientists have developed a new screening technique to help them look for genes that change patients' responses to cancer drugs and other medications.

3 Aug 2004

Smart gene therapy might effectively prevent the organ damage commonly suffered by heart attack victims

Early intervention with a novel kind of "smart gene therapy" might effectively prevent the organ damage commonly suffered by heart attack victims, suggests a new animal study by researchers at Brigham and Women's Hospital in Boston and Duke University Medical Center.

2 Aug 2004

A protein that the body uses to attack the AIDS virus is actually a stealthy defense mechanism that evolved 32 million years before HIV

A protein that the body uses to attack the AIDS virus is actually a stealthy defense mechanism that evolved 32 million years before the emergence of HIV, according to new findings from Fred Hutchinson Cancer Research Center.

2 Aug 2004

Clinical benefit for moderate-to-severe plaque psoriasis patients treated with Raptiva for 30 months

Genentech and XOMA have announced preliminary 30-month (120 weeks) results from an open-label study evaluating the safety and efficacy of long-term continuous treatment with RAPTIVA® (efalizumab) in adults with moderate-to-severe chronic plaque psoriasis.

2 Aug 2004

Scientists create mice that don't gain weight, even when fed fat-laden, high calorie diets

By altering the expression of a single -- albeit different – gene, Drs. Roger Davis (UMASS Medical School, USA) and Ying-Hue Lee (Academia Sinica, Taiwan) have succeeded in creating two different strains of transgenic mice that don't gain weight, even when fed fat-laden, high calorie diets.

2 Aug 2004

Identification of PIK3CA as an oncogene associated with brain cancers opens the door to new screening processes

Hotspots in two areas of a gene that encodes a specific signaling enzyme, or kinase, are vulnerable to a variety of mutations found in five types of brain cancers, according to a report published in the August 1 issue of the journal Cancer Research.

2 Aug 2004

Twin research reveals gene that may play a crucial part in the development of myopia

New research carried out by doctors in the Twin Research Unit at St Thomas’ Hospital, London, indicates that a gene called PAX6 may play a crucial part in the development of myopia.

31 Jul 2004

Important step in understanding the genetic mechanisms of aging

Scientists have rendered the first gene and protein networks of human aging, an important step in understanding the genetic mechanisms of aging. The work led by Joao Pedro de Magalhaes from Harvard Medical School is detailed in the July 30 issue of FEBS Letters.

29 Jul 2004

Gene News and Research

Latest Gene News and Research

First evidence of the molecular link between inflammation and cancer

New gene-silencing technique

Protein loss plays role in acute T-cell leukemia

Successfully cloning mice from an advanced melanoma cell

Mothers who catch a flu during pregnancy may increase the risk of their child developing schizophrenia

New gene therapy treatment involves injecting Herpes simplex virus into the brain tumours of Glioma patients

Entirely new approach to the treatment of aging

New Drug Application with the U.S. Food and Drug Administration for Tarceva

New screening technique to look for genes that change patients' responses to cancer drugs and other medications

Smart gene therapy might effectively prevent the organ damage commonly suffered by heart attack victims

A protein that the body uses to attack the AIDS virus is actually a stealthy defense mechanism that evolved 32 million years before HIV

Clinical benefit for moderate-to-severe plaque psoriasis patients treated with Raptiva for 30 months

Scientists create mice that don't gain weight, even when fed fat-laden, high calorie diets

Identification of PIK3CA as an oncogene associated with brain cancers opens the door to new screening processes

Twin research reveals gene that may play a crucial part in the development of myopia

Important step in understanding the genetic mechanisms of aging

Research to develop ways to inhibit head and neck cancers, the fifth most common cancer worldwide

Proof of principle that it is possible to deliver new genes body-wide to all the muscles of an adult animal

Patent pending botanical extract, V38-AMF-1, completely inhibits bird flu (H5N1) and Fujian Flu

Further evidence about how estrogen helps activate breast cancer

eBook: Using iPSCs models for human disease research and drug discovery eBook

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves