Gene News and Research

Latest Gene News and Research

FORT-2 trial shows promising results for bladder cancer immunotherapy combination

Findings from the international FORT-2 clinical trial showed that a combination treatment including immunotherapy is safe and tolerable in patients with locally advanced or metastatic bladder cancer.

19 Sep 2024

Chan Zuckerberg initiative joins Scale Bio's ‘100 Million Cell Challenge’ to accelerate single cell genomics research

The '100 Million Cell Challenge' invites proposals for large-scale single cell studies, with CZI funding 50 million cells to accelerate scientific discoveries.

19 Sep 2024

Early intervention key for mental health in children with cystic fibrosis

A University at Buffalo psychiatrist who has played a critical role in getting mental health screening and treatment integrated into routine care for adults and adolescents with cystic fibrosis (CF) has been awarded $3 million from the Cystic Fibrosis Foundation to focus on the mental health of children with the disease.

19 Sep 2024

Asimov launches AAV Edge, a suite of AI models, host cells, and genetic tools for end-to-end gene therapy development

Asimov, the synthetic biology company advancing the design and production of therapeutics, today announced the launch of the AAV Edge System, a comprehensive suite of tools for adeno-associated viral (AAV) gene therapy design and manufacturing.

18 Sep 2024

Direct breastfeeding boosts microbial transfer to very-low-birth-weight infant guts

Researchers found that 30-40% of the very-low-birth-weight infant's gut microbiota came from the mother’s milk, and direct breastfeeding enhances microbial transmission despite antibiotic exposure.

18 Sep 2024

Study helps explain why having ApoE4 increases risk of neurodegeneration

A new study helps explain why having ApoE4—the gene variant most closely linked to Alzheimer's disease—increases the risk of neurodegeneration and white matter damage.

18 Sep 2024

Scientists pinpoint thousands of gene variants linked to breast and ovarian cancer risk

Scientists have pinpointed thousands of genetic changes in a gene that may increase a person's risk of developing breast and ovarian cancer, paving the way for better risk assessment and more personalised care.

18 Sep 2024

MicroRNA profiles help assess cancer risk in Lynch syndrome carriers

In his doctoral dissertation completed at the University of Jyväskylä, Finland, Tero Sievänen demonstrates that the cancer risk of Lynch syndrome carriers can be assessed based on circulating microRNA profiles.

18 Sep 2024

Exposure to styrene and ethylbenzene elevates diabetes risk

Type 2 diabetes mellitus (T2DM) is a critical public health issue, with its prevalence expected to rise sharply worldwide.

18 Sep 2024

Study paves way for revolutionizing the management of muscle disorders

The type 1 ryanodine receptor (RyR1) is an important calcium release channel in skeletal muscles essential for muscle contraction.

18 Sep 2024

Discovery of 5-formylcytosine as an activating epigenetic switch

The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early embryonic development.

18 Sep 2024

$1 million grant awarded to explore myelin repair mechanisms in multiple sclerosis

The National Multiple Sclerosis Society (USA) has awarded a grant of 1 million dollars to Dr. Isabel Pérez-Otaño, who leads the Plasticity and Remodeling of Neural Circuits laboratory at the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) of Elche.

18 Sep 2024

Impact of oxidative stress, gut, and diet on attention deficit hyperactivity disorder pathophysiology

Oxidative stress and gut microbiome interactions are key in ADHD pathogenesis, with diet playing a crucial role in managing symptoms and improving outcomes.

18 Sep 2024

Lipid molecule fuels cancer growth

Cancer cells seldom start off stealthy. Quite to the contrary, they announce their presence to the immune system by planting chemical red flags right on their membranes. Once alerted, the body's defenses can swoop in, destroying rogue cells before they can do much damage. Lying at the heart of this early warning system are lipids, fatty compounds previously seen by cancer biologists primarily as a fuel source for burgeoning tumors.

18 Sep 2024

Study uncovers ancestry-specific genetic links to multiple sclerosis risk

A landmark study has uncovered novel ancestry-specific genetic variants linked to multiple sclerosis (MS), offering new insights that could reshape treatment approaches for diverse populations affected by the disease.

17 Sep 2024

Discovery of gene variant could transform treatment for newborn jaundice

One in eight newborn babies has a gene variant that almost completely protects against jaundice. The research, conducted at the University of Gothenburg in Sweden, provides the opportunity to develop a treatment that can prevent severe cases of jaundice.

17 Sep 2024

The Key Role of iPSC-Derived Microglia in Research and Drug Discovery

Dr. Tilman explains the functions of iPSC-derived microglia and their relevance to conditions like Alzheimer’s.

From Axol Bioscience Ltd 17 Sep 2024

Revolutionizing disease prediction: MILTON framework utilizes biobank datasets to identify 3,213 diseases

By integrating multi-omics data, MILTON improves disease prediction and biomarker identification, advancing the field of preventative medicine and diagnostics.

17 Sep 2024

INTEGRA Biosciences’ pipettes pave the way for epigenetics testing

Genknowme, a start-up specializing in epigenetics research, has integrated multichannel pipettes from INTEGRA Biosciences into its liquid handling workflows. These liquid handling solutions will enable the lab to provide fast epigenetic assessments that will support healthcare professionals in suggesting lifestyle changes to improve their patients’ quality of life.

From INTEGRA Biosciences 17 Sep 2024

Cell rejuvenation atlas unveils master regulators of rejuvenation strategies

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 17 on September 9, 2024, entitled, "The cell rejuvenation atlas: leveraging network biology to identify master regulators of rejuvenation strategies."

16 Sep 2024

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Gene News and Research

Latest Gene News and Research

FORT-2 trial shows promising results for bladder cancer immunotherapy combination

Chan Zuckerberg initiative joins Scale Bio's ‘100 Million Cell Challenge’ to accelerate single cell genomics research

Early intervention key for mental health in children with cystic fibrosis

Asimov launches AAV Edge, a suite of AI models, host cells, and genetic tools for end-to-end gene therapy development

Direct breastfeeding boosts microbial transfer to very-low-birth-weight infant guts

Study helps explain why having ApoE4 increases risk of neurodegeneration

Scientists pinpoint thousands of gene variants linked to breast and ovarian cancer risk

MicroRNA profiles help assess cancer risk in Lynch syndrome carriers

Exposure to styrene and ethylbenzene elevates diabetes risk

Study paves way for revolutionizing the management of muscle disorders

Discovery of 5-formylcytosine as an activating epigenetic switch

$1 million grant awarded to explore myelin repair mechanisms in multiple sclerosis

Impact of oxidative stress, gut, and diet on attention deficit hyperactivity disorder pathophysiology

Lipid molecule fuels cancer growth

Study uncovers ancestry-specific genetic links to multiple sclerosis risk

Discovery of gene variant could transform treatment for newborn jaundice

The Key Role of iPSC-Derived Microglia in Research and Drug Discovery

Revolutionizing disease prediction: MILTON framework utilizes biobank datasets to identify 3,213 diseases

INTEGRA Biosciences’ pipettes pave the way for epigenetics testing

Cell rejuvenation atlas unveils master regulators of rejuvenation strategies

eBook: Using iPSCs models for human disease research and drug discovery eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production