Genetics News and Research

Latest Genetics News and Research

Research shows link between clock genes and vitamin A pathway in the brain of Monarch butterflies

Biologists at Texas A&M University are making strides in understanding biological clock function in several model organisms and translating these studies into broader implications for human health.

6 Dec 2019

Scientists uncover new link between pathways involved in RNA degradation

A recent study by a team of scientists in Korea reveals new findings about how various systems involved in cellular surveillance interact. This research is the first to identify a "cross-talk" molecule between these systems. Because these pathways are involved in fighting toxic cellular or foreign substances, the study has various potential applications in antiviral development, gene therapy, and agriculture.

6 Dec 2019

New approach can improve the activity of CAR-T cells against blood and solid cancers

A new approach to programing cancer-fighting immune cells called CAR-T cells can prolong their activity and increase their effectiveness against human cancer cells grown in the laboratory and in mice, according to a study by researchers at the Stanford University School of Medicine.

5 Dec 2019

Time-restricted eating can help treat metabolic syndrome

Metabolic syndrome affects nearly 30 percent of the U.S. population, and increases the risk for type 2 diabetes, heart disease and stroke. But lifestyle interventions such as adopting a healthy diet and increasing physical exercise are difficult to maintain and, even when combined with medication, are often insufficient to fully manage the disease.

5 Dec 2019

Tel Aviv Professor receives Young Investigator Award for contributions in melanoma research

Tel Aviv University's Prof. Carmit Levy received the prestigious Young Investigator Award at the 16th International Congress of the Society for Melanoma Research, held November 20-23 in Salt Lake City, Utah, for her "contributions to melanoma research that significantly exceeded the average for this career stage."

5 Dec 2019

Baylor researchers report creation of an 'epigenetic couch potato' mouse

Why is it that some people love to exercise, and others hate it? Most people would assume it's all due to genetics, but a new Baylor College of Medicine led study in mice shows for the first time that a different molecular level of regulation - epigenetics - plays a key role in determining one's innate drive to exercise.

4 Dec 2019

Ground breaking discovery could lead to new anti TB drugs

New drugs to treat strains of TB which have become resistant to treatment are now a possibility following a ground breaking discovery from the University of Surrey.

4 Dec 2019

Researchers create 3D liver model for improved diagnosis of non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and distinguishing different stages of the disease. However, this technique provides only two-dimensional images of the liver tissue in low resolution and overlooks potentially important 3D structural changes.

4 Dec 2019

Zebrafish study supports accuracy of CRISPR-Cas9 gene editing tool

Along with the promise that CRISPR-Cas9 gene editing technology can offer new human therapies is the need to ensure its safety. A recent study showed that CRISPR-Cas9 did not produce off-target gene mutations in zebrafish. These results, published in Frontiers in Genetics, confirm previous data in animal models that the risk to the rest of the genome from gene editing is minimal.

3 Dec 2019

Multiple mechanisms at work in diabetes drug metformin

Metformin is the most commonly prescribed type 2 diabetes drug, yet scientists still do not fully know how it works to control blood sugar levels. In a collaborative effort, researchers from the Salk Institute, The Scripps Research Institute and Weill Cornell Medical College have used a novel technology to investigate why it functions so well.

3 Dec 2019

75-year old blood-stained microscope slide reveals historical spread of malaria

DNA from 75-year old eradicated European malaria parasites uncovers the historical spread of one of the two most common forms of the disease, Plasmodium vivax, from Europe to the Americas during the colonial period, finds a new study co-led by UCL.

2 Dec 2019

Scientists discover new principle for activation of cancer genes

Researchers have long known that some genes can cause cancer when overactive, but exactly what happens inside the cell nucleus when the cancer grows has so far remained enigmatic.

2 Dec 2019

Research findings provide novel therapeutic space to induce scarless regenerative healing

Abnormal scarring is a serious threat resulting in non-healing chronic wounds or fibrosis. Scars form when fibroblasts, a type of cell of connective tissue, reach wounded skin and deposit plugs of extracellular matrix.

27 Nov 2019

Study finds autism-related genetic mutations in aging brains of Alzheimer's patients

Researchers believe that autism is caused by mutations that occur sporadically in the egg or sperm or during pregnancy.

26 Nov 2019

Mcl-1 inhibition blocks cell survival in ER+ breast cancers

While estrogen receptor - + breast cancers express high levels of three anti-apoptotic Bcl-2 family members, pharmacological inhibition of Bcl-2 and/or Bcl-xL fails to induce cell death in ER + breast cancer cell lines, due to rapid and robust Mcl-1 upregulation.

26 Nov 2019

Diabetes curriculum may help empower students to make healthy choices

For Lola McPherren, learning about diabetes is personal. The Juanita High School ninth-grader had a grandfather with diabetes. She recalled that he gave himself a shot of insulin before a meal, and that he also never really changed his diet to help control the disease. He died in February.

25 Nov 2019

Researchers discover cellular origins of pediatric brain tumors

A research team led by Dr. Claudia Kleinman, an investigator at the Lady Davis Institute at the Jewish General Hospital, together with Dr. Nada Jabado, of the Research Institute of the McGill University Health Centre, and Dr. Michael Taylor, of The Hospital for Sick Children, discovered that several types of highly aggressive and, ultimately, fatal pediatric brain tumors originate during brain development.

25 Nov 2019

Discovery in C. difficile biology opens new window to developing treatments for dangerous infections

A process called sporulation that helps the dangerous bacterium Clostridium difficile (C. difficile) to survive inhospitable conditions and spread is regulated by epigenetics, factors that affect gene expression beyond the DNA genetic code, researchers at the Icahn School of Medicine at Mount Sinai report.

25 Nov 2019

People with salmonella infection more likely to be hospitalized longer

Salmonella is acting up in Michigan, and it could be a model for what's happening in other states, according to a new Michigan State University study.

25 Nov 2019

Air pollution associated with greater risk of glaucoma

Living in a more polluted area is associated with a greater likelihood of having glaucoma, a debilitating eye condition that can cause blindness, finds a new UCL-led study in the UK.

25 Nov 2019

Genetics News and Research

Latest Genetics News and Research

Research shows link between clock genes and vitamin A pathway in the brain of Monarch butterflies

Scientists uncover new link between pathways involved in RNA degradation

New approach can improve the activity of CAR-T cells against blood and solid cancers

Time-restricted eating can help treat metabolic syndrome

Tel Aviv Professor receives Young Investigator Award for contributions in melanoma research

Baylor researchers report creation of an 'epigenetic couch potato' mouse

Ground breaking discovery could lead to new anti TB drugs

Researchers create 3D liver model for improved diagnosis of non-alcoholic fatty liver disease

Zebrafish study supports accuracy of CRISPR-Cas9 gene editing tool

Multiple mechanisms at work in diabetes drug metformin

75-year old blood-stained microscope slide reveals historical spread of malaria

Scientists discover new principle for activation of cancer genes

Research findings provide novel therapeutic space to induce scarless regenerative healing

Study finds autism-related genetic mutations in aging brains of Alzheimer's patients

Mcl-1 inhibition blocks cell survival in ER+ breast cancers

Diabetes curriculum may help empower students to make healthy choices

Researchers discover cellular origins of pediatric brain tumors

Discovery in C. difficile biology opens new window to developing treatments for dangerous infections

People with salmonella infection more likely to be hospitalized longer

Air pollution associated with greater risk of glaucoma

Sequencing & Genomics: Elevating Science and Healthcare eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production