Genetics News and Research

Latest Genetics News and Research

Enzyme important in fetal heart-cell failure - findings provide new targets for treatment

In almost all forms of heart failure, the heart begins to express genes that are normally only expressed in the fetal heart. Researchers have known for years that this fetal-gene reactivation happens, yet not what regulates it.

18 Feb 2007

Largest collection of autism DNA

Preliminary findings from the largest genome scan ever completed in the history of autism research are being published in Nature Genetics. University of Pittsburgh researchers with a consortium of scientists from across the world contributed to this landmark research endeavor through the Autism Genome Project.

18 Feb 2007

New targets in cancer mutation puzzle

University of Rochester scientists, while investigating the two most frequent types of mutations in cancer, discovered a possible new route to treatment that would take advantage of the mutations instead of trying to repair them.

18 Feb 2007

New Kaiser Permanente research aims to reveal genetic and environmental causes behind deadly and disabling diseases

The Kaiser Permanente Northern California Division of Research is launching one of the largest research projects in the United States to examine the genetic and environmental factors that influence common diseases such as heart disease, cancer, diabetes, high blood pressure, Alzheimer's disease, asthma and many others.

15 Feb 2007

Shortening chromosomes cause for earlier cancer onset in families with Li-Fraumeni syndrome

In families with a high incidence of Li-Fraumeni syndrome, the ends of individuals' chromosomes act somewhat like a lit fuse, according to researchers at The Hospital for Sick Children in Toronto. Their findings detail how telomeres, the ends of the chromosomes, shorten with every successive generation, leading to more severe cancers at an earlier age.

15 Feb 2007

Mechanism driving iron overload in thalassemia identified

Led by researchers at Weill Cornell Medical College in New York City, an international group of scientists has pinpointed a specific genetic relationship as the cause of dangerous iron overload in persons with a form of the inherited blood disease, beta-thalassemia.

14 Feb 2007

New patented technology for next generation of DNA and RNA microarrays

A novel invention developed by a scientist from New York Institute of Technology (NYIT) could revolutionize biological and clinical research and may lead to treatments for cancer, AIDS, Alzheimer's, diabetes, and genetic and infectious diseases.

13 Feb 2007

Biochip allows genes to express themselves

Biochip platforms that work as artificial cells are attractive for medical diagnostics, interrogation of biological processes, and for the production of important biomolecules.

13 Feb 2007

Variation in gene caspase-8 may help protect against breast cancer

A large-scale analysis of data on breast cancer risk has concluded that a common variation in the gene caspase-8 (CASP8) is associated with a somewhat lower risk of the disease. Variants are small changes that occur in a gene sequence.

13 Feb 2007

Causes of heart failure

In most cases, heart failure is due to the impaired ability of the heart muscle to pump blood through the body. However, in some cases, the heart no longer functions normally because it is not filled properly. This process is largely determined by the elastic scaffold protein titin.

12 Feb 2007

DNA-encoded antibody libraries

During the past several years, breakthroughs in genomic and proteomic technologies have enabled researchers to more clearly identify the biochemical networks that malfunction when a healthy cell becomes malignant.

12 Feb 2007

GenoMed discovers African gene

GenoMed has announced that it has found the "African gene," responsible for the much higher incidence of diabetes, high blood pressure, and kidney failure among people of African ancestry than whites.

12 Feb 2007

Changes in breast cancer management

Aggressive research currently underway brings hope of dramatic advances in breast cancer management, according to a new review.

12 Feb 2007

Type-2 diabetes genes identified

The most important genes associated with a risk of developing type-2 diabetes have been identified, scientists report today in a new study.

11 Feb 2007

PALB2 gene mutation elevates risk of breast cancer four-fold

Cancer is a complex and common disease caused by a combination of both genetic and environmental factors. An inherited predisposition seems to be involved in at least 5-10 per cent of all cases of breast cancer.

11 Feb 2007

Researchers discover master switch for a tumor suppressive network

A decades-old cancer mystery has been solved by researchers at Cold Spring Harbor Laboratory (CSHL). "We not only found a critical tumor suppressor gene, but have revealed a master switch for a tumor suppressive network that means more targeted and effective cancer therapy in the future," said CSHL Associate Professor Alea Mills, Ph.D.

11 Feb 2007

New method of screening tumors for cancer-related gene abnormalities

A study led by researchers at Dana-Farber Cancer Institute and Broad Institute of the Massachusetts Institute of Technology and Harvard University provides the first demonstration of a practical method of screening tumors for cancer-related gene abnormalities that might be treated with "targeted" drugs.

11 Feb 2007

Scientists discover master switches for adult blood stem cells

Johns Hopkins Kimmel Cancer Center scientists have found a set of "master switches" that keep adult blood-forming stem cells in their primitive state.

8 Feb 2007

International consortium to get to heart of coronary artery disease

An international consortium has been launched to tackle coronary artery disease using the latest scientific tools. Funded by the European Commission, the initiative will build on recent advances in genomic science and the understanding of our genes to develop effective strategies for preventing and treating the disease.

7 Feb 2007

Research helps explain origin of self-reactive B cells

Doctors have long wondered why, in some people, the immune system turns against parts of the body it is designed to protect, leading to autoimmune disease.

7 Feb 2007