Genetics News and Research

Latest Genetics News and Research

New virus-based gene therapy delivery system to help fight cancer

A Mayo Clinic research team has devised a new virus-based gene therapy delivery system to help fight cancer. Researchers say their findings will help overcome hurdles that have hindered gene therapy cancer treatments.

27 Sep 2005

Discovered of gene mutations associated with hereditary neuralgic amyotrophy

In a significant advance toward understanding a perplexing and painful neurological disorder, an international team of researchers has discovered gene mutations associated with an inherited chronic pain and weakness syndrome known as hereditary neuralgic amyotrophy (also called HNA).

27 Sep 2005

Possibility of tailored treatments for addiction based on how a person's genes behave

Scientists have learned how a genetic variation long suspected in making some people susceptible to alcoholism and narcotic drug addiction actually does so.

27 Sep 2005

Temperature can regulate the circadian clock in zebrafish

The biological clock controls the circadian rhythms of a wide range of physiological and behavioral processes, from fluctuating hormone levels to sleep - wake cycles and feeding patterns.

27 Sep 2005

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Pharmaceutical companies around the world still come knocking on Renato Baserga, M.D.,'s door. And for good reason.

27 Sep 2005

Farnesyl transferase inhibitors may help chidren with Hutchinson-Gilford progeria syndrome

Johns Hopkins scientists have discovered that a drug currently being tested against cancers might help children with a rare, fatal condition called Hutchinson-Gilford progeria syndrome, which causes rapid, premature aging.

27 Sep 2005

Gene responsible for Neuralgic Amyotrophy identified

Neuralgic Amyotrophy is a painful disorder of the peripheral nervous system. This heritable disease causes prolonged acute attacks of pain in the shoulder or arm, followed by temporary paralysis.

27 Sep 2005

New method to measure circadian cycles

Everyone knows morning people and late-night owls. The variation in individual circadian rhythms is an anecdotal as well as experimentally verified fact. But, until now, to systematically study circadian differences (and thereby hope to rout out the underlying genetic causes), scientists have had to rely on prolonged behavioural observation.

27 Sep 2005

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

...a discovery that could pave the way for more effective cancer treatments.

27 Sep 2005

Nature may play a larger role than nurture when it comes to family relationships

Researchers from the University of Texas at Austin and George Washington University in Washington, D.C., used data on 674 families, each with a same-sex adolescent pair, to evaluate the factors that made up the relationships and individual personalities.

26 Sep 2005

Extreme gene pin-pointed

One teenager likes to snowboard off a cliff. Another prefers to read a book and wouldn't think of trading places. Why these differences exist is a mystery, but for the first time researchers have identified a possible genetic explanation behind risk-seeking behavior.

26 Sep 2005

Mutations in receptor tyrosine kinases provide potential for highly-targeted cancer therapies

Scientists from J. Craig Venter Institute, Ludwig Institute for Cancer Research, and The Johns Hopkins University School of Medicine identified three novel mutations in two receptor tyrosine kinases in glioblastoma tumors using high throughput sequencing.

26 Sep 2005

Simple, fast and effective method of detecting a large number of patients at high risk for hereditary breast/ovarian cancer

One in five women diagnosed with breast or ovarian cancer who seek mammography have a family history of cancer that suggests they may harbor known cancer-causing gene mutations.

26 Sep 2005

Researchers have uncovered a significant contributing factor to interferon resistance of malignant melanoma cells

The finding represents a step forward in understanding the molecular events that govern the growth of this type of cancer and the changes in gene expression and cellular signaling that underlie resistance to established therapies.

26 Sep 2005

Researchers map genetic location that explains why certain blood pressure-lowering drugs aren't effective for some people

"The findings bring us a step closer to developing targeted therapies for patients with high blood pressure who might otherwise be started on medications that won't help," said lead author Sandosh Padmanabhan, Ph.D.

26 Sep 2005

Mutations in the gene, called PIG-A may help identify individuals at high risk for cancer

A new study to detect an elevated rate of mutations in a gene on the X chromosome holds promise for developing a test that could identify individuals at risk for developing cancer.

26 Sep 2005

Scientists reverse memory loss in mice with Alzheimer's

In mice, that had been genetically engineered to develop Alzheimer's disease, scientists were able to reverse the rodents' memory loss by reducing the amount of an enzyme that is crucial for the development of Alzheimer's disease.

26 Sep 2005

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Leaky lymphatic vessels are the leading cause of the adult onset obesity observed in a laboratory model developed by investigators at St. Jude Children's Research Hospital.

26 Sep 2005

"Designer" rats help show how declining estrogen after menopause can affect hypertension

Scientists at Wake Forest University School of Medicine have created a better research rat – the first to enable them to study how declining estrogen after menopause can affect hypertension, heart failure and kidney damage.

26 Sep 2005

Notch1 and Jagged1 genes are likely markers indicating a patient's probable aggressive breast cancer

In a new study, scientists at The Hospital for Sick Children and Princess Margaret Hospital have shown that two genes called Notch1 and Jagged1 are linked to more aggressive breast cancers and that patients are less likely to survive the disease when these two genes are highly expressed.

26 Sep 2005

Genetics News and Research

Latest Genetics News and Research

New virus-based gene therapy delivery system to help fight cancer

Discovered of gene mutations associated with hereditary neuralgic amyotrophy

Possibility of tailored treatments for addiction based on how a person's genes behave

Temperature can regulate the circadian clock in zebrafish

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Farnesyl transferase inhibitors may help chidren with Hutchinson-Gilford progeria syndrome

Gene responsible for Neuralgic Amyotrophy identified

New method to measure circadian cycles

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

Nature may play a larger role than nurture when it comes to family relationships

Extreme gene pin-pointed

Mutations in receptor tyrosine kinases provide potential for highly-targeted cancer therapies

Simple, fast and effective method of detecting a large number of patients at high risk for hereditary breast/ovarian cancer

Researchers have uncovered a significant contributing factor to interferon resistance of malignant melanoma cells

Researchers map genetic location that explains why certain blood pressure-lowering drugs aren't effective for some people

Mutations in the gene, called PIG-A may help identify individuals at high risk for cancer

Scientists reverse memory loss in mice with Alzheimer's

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

"Designer" rats help show how declining estrogen after menopause can affect hypertension

Notch1 and Jagged1 genes are likely markers indicating a patient's probable aggressive breast cancer

eBook: Using iPSCs models for human disease research and drug discovery eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production