Genetics News and Research

Latest Genetics News and Research

Neurologix announces positive interim results of gene therapy clinical trial for patients with Parkinson's disease

Neurologix has announced positive interim results of its landmark gene therapy clinical trial for patients with Parkinson's disease. Neurologix's 12-patient, dose-escalating Phase I trial is the world's first study to use a viral vector (the non-pathogenic adeno-associated virus, or AAV) for the treatment of an adult neurological disease.

26 Sep 2005

How the vertebrate eye, as we know it, has emerged over evolutionary time

The evolution of complex and physiologically remarkable structures such as the vertebrate eye has long been a focus of intrigue and theorizing by biologists.

26 Sep 2005

Delicate balance of induction and inhibition in determining tooth cusps

One of the remaining challenges for evolutionary developmental studies of mammals, whose evolution is best known from their teeth, is how their tooth shape is altered during development.

26 Sep 2005

Raf Kinase Inhibitor Protein plays a role in controlling the active movement of cells

University of Illinois at Chicago researchers report that a protein that regulates key signaling pathways in cells also plays a role in controlling the active movement or migration of cells. The finding may suggest new pharmaceutical therapies for treating a variety of diseases, including cancer.

26 Sep 2005

Change in gene may be underlying molecular defect in some colorectal cancers

Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer, according to a new study in the current issue of the Journal of the National Cancer Institute.

22 Sep 2005

Definitive multiple sclerosis linkage screen

A cluster of genes on chromosome six is the only one that plays a significant role in multiple sclerosis (MS), according to the most complete genetic study to date in the disorder, presented at the 130th annual meeting of the American Neurological Association in San Diego.

22 Sep 2005

$Genetic factors influence elderly individual's propensity to bone fractures$

Genetic factors influence elderly individual's propensity to bone fractures

The importance of genetic factors in an elderly individual's propensity to bone fractures depends on the individual's age and the type of fracture, according to a study in the Archives of Internal Medicine.

21 Sep 2005

Next generation of effective viral-based therapies for cancer

Researchers at Columbia University Medical Center continue to make strides in their work to develop the next generation of effective viral-based therapies for cancer.

21 Sep 2005

Simple organism can produce 10 trillion varieties of a single protein

A team led by University of California, San Diego biochemists has discovered the mechanism by which a simple organism can produce 10 trillion varieties of a single protein, a finding that provides a new tool to develop novel drugs.

21 Sep 2005

Antibiotic resistance has put humans in an escalating 'arms race' with infectious bacteria

...as scientists try to develop new antibiotics faster than the bacteria can evolve new resistance strategies. But now, researchers have a new strategy that may give them a leg up in the race -- reproducing in the lab the natural evolution of the bacterial enzymes that confer resistance.

21 Sep 2005

Increased ovarian cancer risk not linked to cancer family history

Women with a strong family history of breast cancer but who don't have breast cancer genetic mutations can now be reassured that they are not at increased risk for ovarian cancer, according to a new study by researchers at Memorial Sloan-Kettering Cancer Center (MSKCC).

21 Sep 2005

Study reveals critical molecular events in the origin of fat cells

A new study reveals critical molecular events in the origin of fat cells. The findings are central to understanding chronic diseases, such as obesity and diabetes, as fat cells produce hormones critical for metabolic control, the researchers said.

21 Sep 2005

First true animal model for psoriasis

Scientists at the Research Institute of Molecular Pathology in Vienna have developed the first true animal model for psoriasis and have been able to address the initial steps and possible causes of the disease.

20 Sep 2005

Gene mutation may increase the risk of prostate cancer up to three times in African-American

Researchers have identified a gene mutation that may increase the risk of prostate cancer up to three times in African-American men with a family history of the disease.

20 Sep 2005

Change in gene may be underlying molecular defect in some colorectal cancers

Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer, according to a new study in the September 21 issue of the Journal of the National Cancer Institute.

20 Sep 2005

New research adds to the emerging range of functions that miRNAs perform in an organism

In an effort to understand the biological function of the microRNA mir1, Drs. Nicholas Sokol and Victor Ambros (Darmouth Medical School) have studied the expression profile, transcriptional regulation and loss-of-function phenotype of Drosophila mir-1 (Dmir-1).

20 Sep 2005

Suppression of FOXO1a gene might kill resistant alveolar rhabdomyosarcoma (ARMS) tumors

FOXO1a caused death of tumor cells in laboratory study by triggering expression of caspase-3, which blocks cell division and causes cells to undergo apoptosis, according to St. Jude.

20 Sep 2005

Researchers identify gene prevalent in the population that controls the clinical severity of asthma

The study by Bucala and his colleagues in Dublin, Ireland, included experiments in mice that are resistant to developing asthma because they lack the gene, and an examination of a human population in Dublin chosen for their similar ethnic and geographic identity.

20 Sep 2005

Link between CAPON gene and schizophrenia

We have known for a long time that there is a genetic component to schizophrenia, but nailing down the gene(s) has not been easy.

20 Sep 2005

PUMA protein offers critical insights for developing new anti-cancer drugs

The discovery of how the activities of the protein p53 initiate signals that trigger cell suicide offers critical insights for developing new anti-cancer drugs, according to investigators from St. Jude Children's Research Hospital.

20 Sep 2005

Genetics News and Research

Latest Genetics News and Research

Neurologix announces positive interim results of gene therapy clinical trial for patients with Parkinson's disease

How the vertebrate eye, as we know it, has emerged over evolutionary time

Delicate balance of induction and inhibition in determining tooth cusps

Raf Kinase Inhibitor Protein plays a role in controlling the active movement of cells

Change in gene may be underlying molecular defect in some colorectal cancers

Definitive multiple sclerosis linkage screen

Genetic factors influence elderly individual's propensity to bone fractures

Next generation of effective viral-based therapies for cancer

Simple organism can produce 10 trillion varieties of a single protein

Antibiotic resistance has put humans in an escalating 'arms race' with infectious bacteria

Increased ovarian cancer risk not linked to cancer family history

Study reveals critical molecular events in the origin of fat cells

First true animal model for psoriasis

Gene mutation may increase the risk of prostate cancer up to three times in African-American

Change in gene may be underlying molecular defect in some colorectal cancers

New research adds to the emerging range of functions that miRNAs perform in an organism

Suppression of FOXO1a gene might kill resistant alveolar rhabdomyosarcoma (ARMS) tumors

Researchers identify gene prevalent in the population that controls the clinical severity of asthma

Link between CAPON gene and schizophrenia

PUMA protein offers critical insights for developing new anti-cancer drugs

Sequencing & Genomics: Elevating Science and Healthcare eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production