Huntington's Disease News and Research

Latest Huntington's Disease News and Research

BrainMap analysis strongly affirms 'network degeneration hypothesis' theory

The brain possesses a complex architecture of functional networks as its information-processing machinery. Is the brain's network architecture itself a target of disease? If so, which networks are associated with which diseases? What can this tell us about the underlying causes of brain disorders?

29 Apr 2021

“Expansion Hunter” method can detect DNA errors that lead to repeat expansion diseases

Detecting hidden genetic defects by applying an existing method to an existing datasets. Researchers at Radboud university medical center have succeeded.

16 Apr 2021

Targeting brain protein may lead to new therapeutic approaches for neurodegenerative disorders

Neurological disorders are the number one cause of disability in the world, leading to seven million deaths each year. Yet few treatments exist for these diseases, which progressively diminish a person's ability to move and think.

16 Apr 2021

New consortium aims to accelerate development of stem cell-based therapies for Huntington’s disease

The Stem Cells for Huntington's Disease (SC4HD) is a new international consortium created to promote advanced therapy medicinal product (ATMP) through cell transplantation studies on Huntington's Disease.

9 Apr 2021

Major CIHR grant to help find and tackle the root cause of neurodegenerative disease

Dr. Simonetta Sipione, GlycoNet Investigator and Professor in the Department of Pharmacology at the University of Alberta, was recently awarded a major five-year grant from the Canadian Institutes of Health Research, worth $1.04 million.

26 Mar 2021

Optimized nano-micelles can induce efficient genome editing in the mouse brain

The research group of Deputy Principal Research Scientist Dr. Satoshi Uchida (Associate Professor, Kyoto Prefectural University of Medicine) at the Innovation Center of NanoMedicine (Director General: Prof. Kazunori Kataoka, Location: Kawasaki-Japan, Abbreviation: iCONM) reported that optimized nano-micelles can induce efficient genome editing in the mouse brain.

12 Mar 2021

Optimized nano-micelles can induce efficient genome editing in the mouse brain

12 Mar 2021

Study shows how mutant huntingtin protein triggers brain cell death

In 1993, scientists discovered that a single mutated gene, HTT, caused Huntington's disease, raising high hopes for a quick cure. Yet today, there's still no approved treatment.

7 Mar 2021

Study demonstrates intricate relationship between Prpf19 and Exoc7 in inherited ataxias

Spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph Disease (MJD), describes the most common form of dominantly inherited ataxia in many populations worldwide, including Hong Kong and mainland China.

1 Mar 2021

Study identifies potential therapeutic target for treatment of Huntington's disease

Huntington's disease is caused by a mutation in the Huntingtin gene (HTT), which appears in adults and features motor, cognitive and psychiatric alterations.

23 Feb 2021

Research provides insight into protein structures that could treat Huntington’s disease

In Huntington's disease, a faulty protein aggregates in brain cells and eventually kills them. Such protein aggregates could, in principle, be prevented with a heat shock protein. However, it is not well known how these proteins interact with the Huntington's disease protein.

12 Feb 2021

Study addresses multiple challenges of the pathogenesis of Huntington's disease

Recent genetic data from patients with Huntington's disease (HD) show that DNA repair is an important factor that determines how early or late the disease occurs in individuals who carry the expanded CAG repeat in the HTT gene that causes HD.

12 Feb 2021

New guidance to provide mental health support for people with neurodegenerative conditions

Lancaster University together with the British Psychological Society has provided research-based recommendations for mental health support for people living with four motor neurodegenerative conditions.

2 Feb 2021

Protein alteration contributes to degeneration of neuronal populations in Huntington's disease

Protein alteration in the family of lamins causes several diseases, known as laminopathies, such as progeria or precocious aging.

1 Feb 2021

Cleveland Clinic receives two grants to study therapeutic potential of anti-cancer drug in Alzheimer's

The National Institute of Aging, part of the National Institutes of Health, and the Alzheimer's Drug Discovery Foundation awarded five-year grants of $3.2 million and $1.4 million, respectively, to scientists from Cleveland Clinic Lou Ruvo Center for Brain Health to study the therapeutic potential of the anti-cancer drug lenalidomide in early-stage Alzheimer's disease, known as mild cognitive impairment.

27 Jan 2021

£1.6 million grant awarded to advance development of MND drug candidate

Researchers from the University of Sheffield's Institute for Translational Neuroscience have been awarded a £1.6 million grant from the Medical Research Council.

26 Jan 2021

Study reveals specific neuronal circuits underlying environment-based value learning

How valuable are earmuffs? The answer to this simple question can depend. What brand are they? Are they good quality? What is the weather like? Given the choice between earmuffs and suntan lotion, most people would choose to have the earmuffs on a cold winter day and the lotion on a sunny day at the beach.

22 Jan 2021

Huntington’s disease mutant gene affects brain and body growth in childhood

There is growing evidence to support the hypothesis that there is a neurodevelopmental component to the late-onset neurodegeneration occurring in the brain of huntingtin gene (HTT gene) mutation carriers, and that this increased susceptibility to brain cell death begins during childhood.

6 Jan 2021

Neuroscientists track gene expression to gain insights into drug addiction, Parkinson's disease

Two MIT neuroscientists have received grants from the G. Harold and Leila Y. Mathers Foundation to screen for genes that could help brain cells withstand Parkinson's disease and to map how gene expression changes in the brain in response to drugs of abuse.

4 Jan 2021

Study reveals innovative gene therapy approach to regenerate functional new neurons

Spinal cord injury (SCI) often causes disability and seriously compromises quality of life. While decades of research have made significant progress in axonal regeneration after SCI, most of the interventions have not been translated into clinical therapies.

18 Dec 2020

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

BrainMap analysis strongly affirms 'network degeneration hypothesis' theory

“Expansion Hunter” method can detect DNA errors that lead to repeat expansion diseases

Targeting brain protein may lead to new therapeutic approaches for neurodegenerative disorders

New consortium aims to accelerate development of stem cell-based therapies for Huntington’s disease

Major CIHR grant to help find and tackle the root cause of neurodegenerative disease

Optimized nano-micelles can induce efficient genome editing in the mouse brain

Optimized nano-micelles can induce efficient genome editing in the mouse brain

Study shows how mutant huntingtin protein triggers brain cell death

Study demonstrates intricate relationship between Prpf19 and Exoc7 in inherited ataxias

Study identifies potential therapeutic target for treatment of Huntington's disease

Research provides insight into protein structures that could treat Huntington’s disease

Study addresses multiple challenges of the pathogenesis of Huntington's disease

New guidance to provide mental health support for people with neurodegenerative conditions

Protein alteration contributes to degeneration of neuronal populations in Huntington's disease

Cleveland Clinic receives two grants to study therapeutic potential of anti-cancer drug in Alzheimer's

£1.6 million grant awarded to advance development of MND drug candidate

Study reveals specific neuronal circuits underlying environment-based value learning

Huntington’s disease mutant gene affects brain and body growth in childhood

Neuroscientists track gene expression to gain insights into drug addiction, Parkinson's disease

Study reveals innovative gene therapy approach to regenerate functional new neurons

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

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