Huntington's Disease News and Research

Latest Huntington's Disease News and Research

New technology helps trace the origin of Huntington's disease

The first signs of Huntington's, an inherited disease that slowly deteriorates bodies and minds, don't typically surface until middle age.

18 Sep 2019

Apathy can be used as biomarker of Huntington's disease progression

Researchers from the brain cognition and plasticity group of the Bellvitge Biomedical Research Institute and the Neuroscience Institute of the University of Barcelona have led an innovative study that identifies modifications in the connectivity of cerebral white matter associated with the heterogeneous nature of apathy in Huntington's disease, making it possible to use this syndrome as a biomarker of disease progression.

6 Sep 2019

Salk researchers develop new gene-editing tool to target broad range of mutations, cell types

The ability to edit genes in living organisms offers the opportunity to treat a plethora of inherited diseases. However, many types of gene-editing tools are unable to target critical areas of DNA, and creating such a technology has been difficult as living tissue contains diverse types of cells.

26 Aug 2019

Prion disease in mice treated successfully with antisense oligonucleotides

Prion proteins are known to cause scrapie – a neurodegenerative condition. It is capable of debilitating damage to the nervous system. Researchers have successfully devised a treatment for this condition which prolonged the lives of the lab mice infected with the prions.

1 Aug 2019

Nanoparticles used to deliver CRISPR gene editing tools into the cell

Researchers from Tufts University and the Chinese Academy of Sciences have developed a novel method to effectively deliver the CRISPR/Cas9 (clustered regularly interspaced short palindromic repeat (CRISPR) associated protein 9) gene editing tools into the liver for genetic studies.

15 Jul 2019

Researchers develop first blood-brain barrier chip using stem cells

Researchers at Ben-Gurion University of the Negev and Cedars-Sinai Medical Center in Los Angeles have, for the first time, duplicated a patient's blood-brain barrier, creating a human BBB chip with stem cells, which can be used to develop personalized medicine and new techniques to research brain disorders.

13 Jun 2019

Study searches for the origins of depressive symptoms in Huntington's disease

About 40% of the affected patients with Huntington's disease -a neurodegenerative pathology- show depression symptoms, even in early stages before the apparition of the typical motor symptoms of the disease.

31 May 2019

Study sheds light on design of pharmacological strategies to treat depression in Huntington's disease

About 40 % of the affected patients with Huntington's disease -a neurodegenerative pathology- show depression symptoms, even in early stages before the apparition of the typical motor symptoms of the disease.

31 May 2019

Newly discovered mechanism sheds light on how Parkinson’s disease can spread in the brain

Tiny channels between nerve cells are involved in a newly discovered mechanism of how Parkinson's disease can spread throughout the brain, according to new research from Linköping University, Sweden.

27 May 2019

Study discovers origin of neurofibromas that develop throughout the skin of NF1 patients

A study published today in PLOS ONE discovered the origin of severely disfiguring masses of cells, called neurofibromas, that gradually develop throughout the skin of patients afflicted with Neurofibromatosis 1.

22 May 2019

Study explores why people at risk for Huntington's disease choose not to undergo genetic testing

As many as 90 percent of individuals who have a parent with Huntington's disease (HD) choose not to take a gene test that reveals if they will also develop the fatal disorder -- and a new study details the reasons why.

17 May 2019

Scientists discover how mutations in DNA can cause neurodegenerative disease

Scientists have discovered how mutations in DNA can cause neurodegenerative disease. The discovery is an important step towards better treatment to slow the progression or delay onset in a range of incurable diseases such as Huntington's and motor neurone disease - possibly through the use, in new ways, of existing anti-inflammatory drugs.

13 May 2019

Nanotubes enable movement of toxic protein linked to Huntington's disease

A toxic protein linked to Huntington's disease can move from neuron to neuron through a nanotube tunnel whose construction is initiated by a protein called Rhes, say scientists at Scripps Research.

11 May 2019

Drug that treats high blood pressure shows promise against neurodegenerative diseases

A prescribed drug to treat high blood pressure has shown promise against conditions such as Parkinson's, Huntington's and forms of dementia in studies carried out in mice and zebrafish at the University of Cambridge.

19 Apr 2019

A new role for sensory signals in the brain discovered

Learning how to tie a shoe or shoot a basketball isn't easy, but the brain somehow integrates sensory signals that are critical to coordinating movements so you can get it right.

12 Apr 2019

Mutation in Huntington’s disease may alter interactions of Huntingtin protein with Rac1

Since 1993, when the gene that causes Huntington's disease was identified, there has been intense focus on understanding how this genetic mutation causes the disease's severe progressive neural deterioration.

4 Apr 2019

Researchers identify crucial player in controlling misfolded proteins

Researchers have identified a protein complex that marks misfolded proteins, stops them from interacting with other proteins in the cell and directs them towards disposal.

27 Mar 2019

Study shows how cell death can be triggered by a mitochondrial enzyme

Cytochrome c is a small enzyme that plays an important role in the production of energy by mitochondria.

15 Mar 2019

Study reveals how one mutation causes the most common inherited intellectual disability

Research published today (Feb. 11, 2019) reveals how one mutation causes fragile X, the most common inherited intellectual disability.

12 Feb 2019

CIRM announces funding for UCI researchers to develop new treatment for Huntington’s disease

Following a California Institute for Regenerative Medicine Independent Citizens Oversight Committee meeting held last week, University of California, Irvine researchers learned they will receive $6 million in funding to support the continued development of a promising new treatment for Huntington's disease

5 Feb 2019

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

New technology helps trace the origin of Huntington's disease

Apathy can be used as biomarker of Huntington's disease progression

Salk researchers develop new gene-editing tool to target broad range of mutations, cell types

Prion disease in mice treated successfully with antisense oligonucleotides

Nanoparticles used to deliver CRISPR gene editing tools into the cell

Researchers develop first blood-brain barrier chip using stem cells

Study searches for the origins of depressive symptoms in Huntington's disease

Study sheds light on design of pharmacological strategies to treat depression in Huntington's disease

Newly discovered mechanism sheds light on how Parkinson’s disease can spread in the brain

Study discovers origin of neurofibromas that develop throughout the skin of NF1 patients

Study explores why people at risk for Huntington's disease choose not to undergo genetic testing

Scientists discover how mutations in DNA can cause neurodegenerative disease

Nanotubes enable movement of toxic protein linked to Huntington's disease

Drug that treats high blood pressure shows promise against neurodegenerative diseases

A new role for sensory signals in the brain discovered

Mutation in Huntington’s disease may alter interactions of Huntingtin protein with Rac1

Researchers identify crucial player in controlling misfolded proteins

Study shows how cell death can be triggered by a mitochondrial enzyme

Study reveals how one mutation causes the most common inherited intellectual disability

CIRM announces funding for UCI researchers to develop new treatment for Huntington’s disease

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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