Huntington's Disease News and Research

Latest Huntington's Disease News and Research

New genetic screen for Huntington’s disease

Huntington’s disease is a genetic disease that is debilitating and progressive leading to severe brain damage and eventual death. In patients with this autosomal dominant disease, there is presence of a protein called the Huntingtin protein that forms clumps within the brain leading to the symptoms of the disease.

30 Jan 2020

AI analysis of blood samples can predict progression of neurodegenerative disease

Evaluating the effectiveness of therapies for neurodegenerative diseases is often difficult because each patient's progression is different.

28 Jan 2020

Research team identifies new roles for Huntington's Disease protein

A Duke University research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative disorder known as Huntington's Disease.

21 Jan 2020

A molecular switch for repairing damage in central nervous system disorders discovered

A molecular switch has the ability to turn on a substance in animals that repairs neurological damage in disorders such as multiple sclerosis, Mayo Clinic researchers discovered.

11 Jan 2020

A new kind of testing for patients with Parkinson's disease

Parkinson's disease is a neurodegenerative disorder that manifests through symptoms such as tremor, slow movements, limb rigidity and gait and balance problems.

26 Dec 2019

New technique could lead to better diagnosis and effective tracking of Huntington’s disease

Researchers at the universities of Southampton and Cambridge have developed a new technique to analyze biochemical changes unique to Huntington's disease.

17 Dec 2019

University Of Iowa wins $18 million grant to continue study on Huntington's disease

Peg Nopoulos, MD, chair of psychiatry and professor of psychiatry, neurology, and pediatrics in the University of Iowa Carver College of Medicine, has received a five-year, $18 million grant from the National Institute of Neurological Disorders and Stroke to continue and expand a decade-long study on brain development in children at risk for developing Huntington's Disease.

11 Dec 2019

Scientists evaluate mouse models used for developing new treatments for Huntington's disease

Huntington's disease (HD) is an incurable and fatal hereditary disease. Developing disease-modifying drugs to treat patients with HD depends on studying them in animal models. Scientists evaluated the mouse models used for developing new treatments for mood disorders in HD and recommended which of these models are most relevant to their studies.

11 Dec 2019

Huntington's disease patients need to better understand the risks and benefits of new therapies

For patients with Huntington's disease (HD), clinical trials can offer hope when there are no treatments available despite unknowns about whether the therapy will work or is safe.

10 Dec 2019

Researchers uncover novel pathogenic mechanism in Huntington’s disease

Researchers from the Institute of Neurosciences of the University of Barcelona and the August Pi i Sunyer Biomedical Research Institute described a mechanism, the increase of proteinaceous synthesis, which takes part in the degeneration of the type of neurons that are affected in Huntington's disease, a genetic neurodegenerative disease.

20 Nov 2019

Fluorescent carbon dots can effectively detect calcium levels in cells

In hospitals, doctors often advise patients to take calcium supplements. But does the calcium get into the cells that need it? Until recently, it's been hard to tell.

12 Nov 2019

Q-Suite Motor Assessment Tool helps detect subtle motor abnormalities in children

In clinical trials of adults with Huntington's disease (HD) the Q-Suite Motor Assessment Tool (Q-Motor) has proven to be helpful to detect and quantitate subtle motor abnormalities.

22 Oct 2019

Link found between genetic variations and size of the brainstem, other subcortical structures

Researchers have found a link between 48 common genetic variations and the size of the brainstem and other subcortical structures deep within the brain.

21 Oct 2019

Pluripotent stem cells help advance understanding of how Huntington's disease develops

Huntington's disease (HD) is a fatal hereditary disease for which there is no cure. A novel study from Cedars-Sinai Medical Center, Los Angeles, using pluripotent stem cells advances understanding of how the disease develops and may help pave the way for identifying pathways for future treatments.

21 Oct 2019

Patterns unique to the striatum observed in people with Huntington's disease

The part of the brain that selectively degenerates in people with Huntington's disease (HD), called the striatum, is almost entirely destroyed in the late stages of the disease. Brain samples from mutant HD gene positive individuals who had not yet developed symptoms by time of death are extremely rare. As a consequence, very little is known about the active disease process that causes the devastating symptoms of HD.

21 Oct 2019

UCLA research identifies potential strategy that may halt Huntington's disease

A new study examining the role that star-shaped brain cells called astrocytes play in Huntington's disease has identified a potential strategy that may halt the disease and repair some of the damage it causes.

16 Oct 2019

New technology helps trace the origin of Huntington's disease

The first signs of Huntington's, an inherited disease that slowly deteriorates bodies and minds, don't typically surface until middle age.

18 Sep 2019

Apathy can be used as biomarker of Huntington's disease progression

Researchers from the brain cognition and plasticity group of the Bellvitge Biomedical Research Institute and the Neuroscience Institute of the University of Barcelona have led an innovative study that identifies modifications in the connectivity of cerebral white matter associated with the heterogeneous nature of apathy in Huntington's disease, making it possible to use this syndrome as a biomarker of disease progression.

6 Sep 2019

Salk researchers develop new gene-editing tool to target broad range of mutations, cell types

The ability to edit genes in living organisms offers the opportunity to treat a plethora of inherited diseases. However, many types of gene-editing tools are unable to target critical areas of DNA, and creating such a technology has been difficult as living tissue contains diverse types of cells.

26 Aug 2019

Prion disease in mice treated successfully with antisense oligonucleotides

Prion proteins are known to cause scrapie – a neurodegenerative condition. It is capable of debilitating damage to the nervous system. Researchers have successfully devised a treatment for this condition which prolonged the lives of the lab mice infected with the prions.

1 Aug 2019

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

New genetic screen for Huntington’s disease

AI analysis of blood samples can predict progression of neurodegenerative disease

Research team identifies new roles for Huntington's Disease protein

A molecular switch for repairing damage in central nervous system disorders discovered

A new kind of testing for patients with Parkinson's disease

New technique could lead to better diagnosis and effective tracking of Huntington’s disease

University Of Iowa wins $18 million grant to continue study on Huntington's disease

Scientists evaluate mouse models used for developing new treatments for Huntington's disease

Huntington's disease patients need to better understand the risks and benefits of new therapies

Researchers uncover novel pathogenic mechanism in Huntington’s disease

Fluorescent carbon dots can effectively detect calcium levels in cells

Q-Suite Motor Assessment Tool helps detect subtle motor abnormalities in children

Link found between genetic variations and size of the brainstem, other subcortical structures

Pluripotent stem cells help advance understanding of how Huntington's disease develops

Patterns unique to the striatum observed in people with Huntington's disease

UCLA research identifies potential strategy that may halt Huntington's disease

New technology helps trace the origin of Huntington's disease

Apathy can be used as biomarker of Huntington's disease progression

Salk researchers develop new gene-editing tool to target broad range of mutations, cell types

Prion disease in mice treated successfully with antisense oligonucleotides

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

The evolution of OCT for retinal imaging and disease intervention

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

The evolution of OCT for retinal imaging and disease intervention

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