Immunotherapy News and Research

Latest Immunotherapy News and Research

Immunosupressant combination therapy for glioblastoma shows promise

Researchers from the University of Texas have found an immunosuppressing target for the treatment of glioblastoma. In mice studies the team has identified CD73 macrophages which could be used to treat the cancers. The team also performed studies on human tumours to arrive at their conclusions. The study was published in the latest issue of the journal Nature Medicine this week.

23 Dec 2019

Data results of NCI-MATCH trial in tumors with DNA mismatch repair deficiencies

Final results are published from an evaluation of 42 patients treated with the immune checkpoint inhibitor nivolumab in the large multi-arm precision medicine trial, NCI-Molecular Analysis for Therapy Choice (NCI-MATCH or EAY131).

20 Dec 2019

Common immune cell linked to failure of checkpoint inhibitors in lung cancer patients

For many lung cancer patients, the best treatment options involve checkpoint inhibitors. These drugs unleash a patient's immune system against their disease and can yield dramatic results, even in advanced cancers.

19 Dec 2019

FDA approves new drug to treat adults with advanced urothelial or bladder cancer

The U.S. Food & Drug Administration granted accelerated approval to the drug enfortumab vedotin (EV) to treat adult patients with advanced urothelial or bladder cancer.

19 Dec 2019

Scientists create new classification system for tumors

Based on the largest study of cancer patients of its kind, scientists have created a new way of classifying tumors.

19 Dec 2019

Researchers discover a way to move precision immunotherapy forward for multiple myeloma

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way to move precision immunotherapy forward by using genomics to inform immunotherapy for multiple myeloma, a blood cancer, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research, in December.

19 Dec 2019

A new book on ovarian cancer

An opening discussion of contemporary management of this disease presents commentary on surgery and clinical trials: neoadjuvant, dose-dense, and heated intraperitoneal chemotherapy (HIPEC}, as well as immunotherapy, vaccine therapy, emerging therapies.

18 Dec 2019

People allergic to peanuts can safely eat tree nuts, but nearly 40% choose avoidance

A new article in Annals of Allergy, Asthma and Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology shows most people allergic to peanuts can safely eat tree nuts.

18 Dec 2019

New standards needed for improving the design of clinical trials for MS patients

How can the perspectives of patients with multiple sclerosis (MS) be given more consideration in clinical trials? This question was investigated and corresponding recommendations were developed by a working group of the Drug Commission of the German Medical Association, the Charité University Hospital Berlin, and the Institute for Quality and Efficiency in Health Care.

17 Dec 2019

New combination therapy can lead to durable responses in patients with multiple myeloma

An experimental, off-the-shelf immunotherapy that combines a targeted antibody and chemotherapy can lead to potentially durable responses in multiple myeloma patients whose disease has relapsed or is resistant to other standard therapies.

17 Dec 2019

Immunotherapy: A promising new alternative to cancer therapies

Sophie Lucas, a researcher at the University of Louvain (UCLouvain) de Duve Institute, studies the immune responses that cancer patients can develop against their own tumor.

16 Dec 2019

Biocompatible hydrogels could help heal wounds, deliver drugs and treat cancer

Hydrogels for healing, synthesized from the molecules up by Rice University bioengineers, are a few steps closer to the clinic.

16 Dec 2019

UAB seminar on the extraordinary science of the immune system

"The human immune system makes my head explode," Pulitzer Prize-winning journalist Matt Richtel recently told a University of Alabama at Birmingham freshman seminar on immunology. "This is by far the hardest subject I have ever had to explore."

15 Dec 2019

Community-based program enables donation of tumor tissue and blood samples for research

Precision medicine with targeted therapies has led to improved treatment options and patient outcomes. These approaches were developed by studying tumors grown in laboratories and patient samples obtained before and during their treatment.

14 Dec 2019

New strategy could prevent side effects of targeted cancer treatment

Targeted, highly effective cancer treatments often produce debilitating side effects. This is the case with one commonly used therapy which works by blocking the epidermal growth factor receptor, a protein that stimulates cell proliferation.

13 Dec 2019

Dendritic cells could lead to better treatments for persistent infections, cancer

Autoimmune disorders such as rheumatoid arthritis, psoriasis, and Crohn's disease plague tens of millions of Americans and are the result of the body's immune system, whose role is to fight against disease-causing pathogens, turning against itself.

12 Dec 2019

Yale scientists flip the script on novel cancer therapy to find new insights into lupus

In the last decade, scientists discovered that blocking a key regulator of the immune system helped unleash the body's natural defenses against several forms of cancer, opening up a new era of cancer immunotherapy.

11 Dec 2019

New drug combo promises help for triple negative breast cancer patients

A new preclinical study on triple negative breast cancer (TNBC) reports that an experimental polo-like kinase 1 (PLK1) inhibitor shrank tumor four times more powerfully when used along with standard drugs than alone. The study, reported in the journal PLOS ONE, opens up a new door of opportunity for patients with this disease.

11 Dec 2019

Combination regimen shows promising results in preclinical models of triple negative breast cancer

Tumor volume in a preclinical model of triple negative breast cancer (TNBC) was reduced four times more when an experimental polo-like kinase 1 (PLK1) inhibitor was combined with a standard-of-care chemotherapeutic agent than when the agent was used alone.

10 Dec 2019

Immunotherapy more effective than chemotherapy for children, young adults with relapsed B-ALL

New findings from a clinical trial show that treatment with the immunotherapy drug blinatumomab is superior to standard chemotherapy for children and young adults with high- or intermediate-risk B-cell acute lymphoblastic leukemia that has relapsed.

10 Dec 2019

Immunotherapy News and Research

Latest Immunotherapy News and Research

Immunosupressant combination therapy for glioblastoma shows promise

Data results of NCI-MATCH trial in tumors with DNA mismatch repair deficiencies

Common immune cell linked to failure of checkpoint inhibitors in lung cancer patients

FDA approves new drug to treat adults with advanced urothelial or bladder cancer

Scientists create new classification system for tumors

Researchers discover a way to move precision immunotherapy forward for multiple myeloma

A new book on ovarian cancer

People allergic to peanuts can safely eat tree nuts, but nearly 40% choose avoidance

New standards needed for improving the design of clinical trials for MS patients

New combination therapy can lead to durable responses in patients with multiple myeloma

Immunotherapy: A promising new alternative to cancer therapies

Biocompatible hydrogels could help heal wounds, deliver drugs and treat cancer

UAB seminar on the extraordinary science of the immune system

Community-based program enables donation of tumor tissue and blood samples for research

New strategy could prevent side effects of targeted cancer treatment

Dendritic cells could lead to better treatments for persistent infections, cancer

Yale scientists flip the script on novel cancer therapy to find new insights into lupus

New drug combo promises help for triple negative breast cancer patients

Combination regimen shows promising results in preclinical models of triple negative breast cancer

Immunotherapy more effective than chemotherapy for children, young adults with relapsed B-ALL

eBook: The Ultimate Guide to Successful Immunofluorescence eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Immunotherapy News and Research

Latest Immunotherapy News and Research

eBook: The Ultimate Guide to Successful Immunofluorescence eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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