Immunotherapy News and Research

Latest Immunotherapy News and Research

Researchers show how cancer therapy works in different way to destroy tumor cells

Antibodies to the proteins PD-1 and PD-L1 have been shown to fight cancer by unleashing the body's T cells, a type of immune cell.

18 May 2017

Tumor mutation load in patient's biopsy varies by age and type of cancer

A team of investigators led by researchers at Georgetown Lombardi Comprehensive Cancer Center has found that the tumor mutation load, or TML, in a patient's cancer biopsy varied by age and the type of cancer, along with several other factors.

18 May 2017

Major allergens strongly underrepresented in some immunotherapy against bee stings

Summer is approaching, and for many allergy sufferers this means it is time to start fearing bee stings. "Allergic reactions to insect venoms are potentially life-threatening, and constitute one of the most severe hypersensitivity reactions," explains PD Dr. Simon Blank, research group leader at the Center of Allergy & Environment, a joint undertaking by the Helmholtz Zentrum München and the TUM.

17 May 2017

Scientists unravel mystery of T cell signaling process vital to immune response

The immune system cells known as T cells play a central role in the body's ability to fight infections and cancer. For decades, however, details of the molecular signaling process that leads to T cell activation have remained a mystery.

16 May 2017

Scientists discover simple way to use light for steering killer immune cells toward tumors

The science behind harnessing the immune system to fight cancer is complicated, but a University of Rochester Medical Center laboratory discovered a simple, practical way to use light and optics to steer killer immune cells toward tumors.

15 May 2017

Phase 1 clinical studies reveal safety, tolerability of therapeutic vaccine in celiac disease patients

ImmusanT, Inc., a clinical-stage company developing Nexvax2, a therapeutic vaccine intended to protect against the effects of gluten exposure while maintaining a gluten-free diet in HLA-DQ2.5+ patients with celiac disease, today announced the publication of positive data from two Phase 1 clinical trials of Nexvax2 in celiac disease.

12 May 2017

Scientists discover free C3d protein that mitigates tumor-induced immunosuppression

In the body, anti-cancer immunity is immobilized by stealth cancer forces. But a natural de-immobilizer has been identified-;and it has a vendetta.

12 May 2017

Immunoreceptor promotes tumor growth in mouse models of liver cancer driven by inflammation

Boosting a part of the immune system known to have anti-tumor properties may actually help tumors grow in cancers linked to chronic inflammation.

12 May 2017

UC researchers find stem cell vaccine to enhance immune responses against tumors in animal models

Researchers at the University of Cincinnati have found that a cancer stem cell vaccine, engineered to express a pro-inflammatory protein called interleukin-15 (IL-15) and its receptor (IL-15Ralpha), caused T cell production in animal models and enhanced immune responses against tumors.

10 May 2017

New trial aims to prolong remission for pediatric leukemia patients treated with T-cell immunotherapy

After phase 1 results of Seattle Children's Pediatric Leukemia Adoptive Therapy trial have shown T-cell immunotherapy to be effective in getting 93 percent of patients with relapsed or refractory acute lymphoblastic leukemia into complete initial remission, researchers have now opened a first-in-human clinical trial aimed at reducing the rate of relapse after the therapy, which is about 50 percent.

9 May 2017

Mothers infected with malaria during pregnancy can alter infants’ immunity

Mothers infected with malaria during pregnancy can pass more of their own cells to their baby and change the infant's risk of later infection, a new study shows.

9 May 2017

Machine learning could help reduce false positives from mammography screening

Machine learning (or coding) could help reduce false positives from mammography screening, according to an article study published online in the May 4, 2017 issue of the Journal of the American Medical Association Oncology.

8 May 2017

UAB spinoff develops drug-resistant immunotherapy to combat solid tumors

The University of Alabama at Birmingham and two partner institutions have received a European patent for their novel approach to fighting cancer, an approach that is led by the UAB spinoff biopharmaceutical company Incysus Ltd.

5 May 2017

New research identifies immunotherapy targets to offer hope for early-stage lung cancer patients

Immunotherapy, which has achieved remarkable results in late-stage lung cancer patients, can also hold great hope for newly diagnosed patients, cutting the deadly disease off before it has the chance to take hold and offering a potential cure, according to a new Mount Sinai study published today in Cell.

4 May 2017

Study suggests how existing and emerging immunotherapy treatments could be successful for sarcomas

Sarcomas- cancers of the connective tissues like muscles, joints, fat and bone -; come in dozens of subtypes. Clinical trial results have been mixed when treating these diverse tumors with immunotherapy, a targeted therapeutic strategy that has success in other cancers.

3 May 2017

Stereotactic radiation provides effective, noninvasive treatment option for kidney cancer patients

Kidney cancer patients may soon have an alternative to traditional treatments, new research at UT Southwestern Medical Center's Kidney Cancer Program of the Harold C. Simmons Comprehensive Cancer Center shows.

2 May 2017

Mayo Clinic scientists develop novel nanoparticle to shrink tumors, prevent breast cancer recurrence

A Mayo Clinic research team has developed a new type of cancer-fighting nanoparticle aimed at shrinking breast cancer tumors, while also preventing recurrence of the disease.

2 May 2017

UH-led researchers focus on creating durable T cells to make immunotherapy more effective

Immunotherapy, in which cells from the human immune system are unleashed to fight disease, has been the big story in cancer treatment over the past few years. When it works, it can spur long-lasting remission in patients for whom other treatments have failed.

2 May 2017

Noninvasive PET imaging may predict cancer patients’ immunotherapy response early

A noninvasive PET imaging method that measures granzyme B, a protein released by immune cells to kill cancer cells, was able to distinguish mouse and human tumors that responded to immune checkpoint inhibitors from those that did not respond early in the course of treatment.

1 May 2017

Researchers show resident T cells in the skin depend on CD103 molecule for their anti-tumor function

The molecule CD103 is key to the long-term residence of T cells in the skin and to their anti-tumor function, report a team of researchers at the Medical University of South Carolina and the Dartmouth-Hitchcock Norris Cotton Cancer Center In the April 14, 2017, Science Immunology.

28 Apr 2017

Immunotherapy News and Research

Latest Immunotherapy News and Research

Researchers show how cancer therapy works in different way to destroy tumor cells

Tumor mutation load in patient's biopsy varies by age and type of cancer

Major allergens strongly underrepresented in some immunotherapy against bee stings

Scientists unravel mystery of T cell signaling process vital to immune response

Scientists discover simple way to use light for steering killer immune cells toward tumors

Phase 1 clinical studies reveal safety, tolerability of therapeutic vaccine in celiac disease patients

Scientists discover free C3d protein that mitigates tumor-induced immunosuppression

Immunoreceptor promotes tumor growth in mouse models of liver cancer driven by inflammation

UC researchers find stem cell vaccine to enhance immune responses against tumors in animal models

New trial aims to prolong remission for pediatric leukemia patients treated with T-cell immunotherapy

Mothers infected with malaria during pregnancy can alter infants’ immunity

Machine learning could help reduce false positives from mammography screening

UAB spinoff develops drug-resistant immunotherapy to combat solid tumors

New research identifies immunotherapy targets to offer hope for early-stage lung cancer patients

Study suggests how existing and emerging immunotherapy treatments could be successful for sarcomas

Stereotactic radiation provides effective, noninvasive treatment option for kidney cancer patients

Mayo Clinic scientists develop novel nanoparticle to shrink tumors, prevent breast cancer recurrence

UH-led researchers focus on creating durable T cells to make immunotherapy more effective

Noninvasive PET imaging may predict cancer patients’ immunotherapy response early

Researchers show resident T cells in the skin depend on CD103 molecule for their anti-tumor function

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Immunotherapy News and Research

Latest Immunotherapy News and Research

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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