Immunotherapy News and Research

Latest Immunotherapy News and Research

New way of targeting proteins to exosomes - potential for melanoma, Alzheimer's disease

Researchers at the University of Pennsylvania School of Medicine have discovered how a protein called Pmel17 is sorted by pigment cells in the skin and eye to make a fiber matrix that eventually sequesters melanin, the dark pigment found in skin, hair, and eyes.

28 Mar 2006

Is there any role for thalidomide as a monotherapy in the management of metastatic renal cell carcinoma?

Thalidomide remains an enigma in the treatment of metastatic renal cell carcinoma (RCC). Initial clinical trials suggested a benefit, but more recently, subsequent randomized trials studying thalidomide in combination with other agents such as interferon have demonstrated no added benefit.

8 Mar 2006

$1 million of mesothelioma research funding

The Mesothelioma Applied Research Foundation (MARF) has announced awards of almost $1 million in additional research funding aimed at curing mesothelioma.

24 Feb 2006

Selective T cell stimulation could help improve treatment of autoimmune disease and cancer

The findings could also be significant for developing new ways to help patients with autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, or juvenile diabetes.

23 Feb 2006

Interleukin-15 encourages CD8+ T cells to proliferate and reduces their tolerance to tumor antigens

Certain types of white blood cells assist the body in destroying cancerous tumors. Among these are CD8+ T cells. The T is for thymus, the gland near the base of the throat that both raises up and weeds out blood cells involved in immune responses.

20 Feb 2006

Grants bring Mesothelioma research to over $3 million

The Mesothelioma Applied Research Foundation has announced thrilling news for all who care about eradicating the vicious disease. MARF has awarded nine new grants of $100,000 each for exciting research projects commencing in late 2005 aimed at curing mesothelioma ("meso").

13 Feb 2006

Lupus responds to stem cell transplant therapy

Transplanting patients with blood stem cells that originate from their own bone marrow can induce the remission of life-threatening, treatment-resistant lupus, according to a study that took place at Northwestern Memorial Hospital in Chicago.

13 Feb 2006

New technology for accelerating development of vaccines against H5N1 flu

Technology that enables scientists to identify targets for the development of vaccines against viruses such as H5N1 in weeks rather than months has entered a pilot study at ProImmune, Oxford, UK.

7 Feb 2006

Source of crucial immune cell in the skin discovered - may lead to tumor immunotherapy

Mount Sinai School of Medicine researchers have identified the precursors of cells in the skin that are part of the first line of defense against invading pathogens. The study appears on Nature Immunology's website.

7 Feb 2006

New hope for patients with metastatic melanoma

Patients with metastatic melanoma (MM) have new hope, says a recently published study by Mayo Clinic Cancer Center. The study, which shows the combination of paclitaxel and carboplatin (PC) appears to be effective for MM when traditional treatments have failed, is in this month's issue of Cancer.

6 Jan 2006

Research project to advance understanding of how cancer cells evade the immune system

A pre-clinical research project coordinated by The University of Manchester, which will advance understanding of how cancer cells evade the immune system, has been awarded nearly 12m Euro by the EU.

From The University of Manchester 7 Nov 2005

New therapies for prostate cancer

A Dutch study suggested treating prostate cancer patients with higher doses of radiotherapy significantly improved patient outcome and treatment over a five-year period.

3 Nov 2005

Dendritic cells tricked into action against cancer

A new type of immunotherapy in which dendritic cells are tricked into action against cancer when they are exposed to harmless pieces of viruses and bacteria is described in the November issue of Cancer Research.

1 Nov 2005

Reagent under study as cancer vaccine may also help protect tumors

A bacterial mimic under study as a cancer vaccine because it signals the immune system to attack may also help some tumors hide, researchers have found.

1 Nov 2005

Discovery could help make cellular immunotherapy safer

Researchers at the University of Michigan's Comprehensive Cancer Center have discovered the secret weapon behind the most powerful form of cancer immunotherapy known to medicine.

16 Oct 2005

Endocytosis of HIV-1 activates plasmacytoid dendritic cells via toll-like receptor -viral RNA interactions

Progressive disease after HIV infection is inversely correlated with the presence of plasmacytoid dendritic cells (pDCs), a subset of the dendritic cell family and the major producers of type 1 interferon in the body. High numbers of pDCs is related to successful control of HIV.

13 Oct 2005

New monoclonal antibody that targets immune system B cells shows promise for treating leukemias

In studies with mice, treatment with a new monoclonal antibody that targets immune system B cells has shown considerable promise for treating leukemias, autoimmune diseases and transplant rejection, according to immunologists at Duke University Medical Center.

11 Oct 2005

Chicken virus helps develop novel vaccines

Researchers at the University of South Australia are developing novel vaccines by using a chicken virus to either stimulate or suppress the body's immune system.

28 Sep 2005

Cancer vaccine based on the bacterium Listeria monocytogenes, can cure mice with breast tumors

A team from the University of Pennsylvania School of Medicine has shown that by using a cancer vaccine based on the bacterium Listeria monocytogenes, they can cure mice with established breast tumors. Cancer vaccines, which are more properly described as immunotherapy, work by boosting an immune response against tumor-associated antigens.

27 Sep 2005

Researchers have uncovered a significant contributing factor to interferon resistance of malignant melanoma cells

The finding represents a step forward in understanding the molecular events that govern the growth of this type of cancer and the changes in gene expression and cellular signaling that underlie resistance to established therapies.

26 Sep 2005

Immunotherapy News and Research

Latest Immunotherapy News and Research

New way of targeting proteins to exosomes - potential for melanoma, Alzheimer's disease

Is there any role for thalidomide as a monotherapy in the management of metastatic renal cell carcinoma?

$1 million of mesothelioma research funding

Selective T cell stimulation could help improve treatment of autoimmune disease and cancer

Interleukin-15 encourages CD8+ T cells to proliferate and reduces their tolerance to tumor antigens

Grants bring Mesothelioma research to over $3 million

Lupus responds to stem cell transplant therapy

New technology for accelerating development of vaccines against H5N1 flu

Source of crucial immune cell in the skin discovered - may lead to tumor immunotherapy

New hope for patients with metastatic melanoma

Research project to advance understanding of how cancer cells evade the immune system

New therapies for prostate cancer

Dendritic cells tricked into action against cancer

Reagent under study as cancer vaccine may also help protect tumors

Discovery could help make cellular immunotherapy safer

Endocytosis of HIV-1 activates plasmacytoid dendritic cells via toll-like receptor -viral RNA interactions

New monoclonal antibody that targets immune system B cells shows promise for treating leukemias

Chicken virus helps develop novel vaccines

Cancer vaccine based on the bacterium Listeria monocytogenes, can cure mice with breast tumors

Researchers have uncovered a significant contributing factor to interferon resistance of malignant melanoma cells

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

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Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

Immunotherapy News and Research

Latest Immunotherapy News and Research

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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